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Entry version 31 (16 Oct 2019)
Sequence version 1 (22 Jul 2015)
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Protein
Submitted name:

Dynein heavy chain domain 1

Gene

Dnhd1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dynein heavy chain domain 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dnhd1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Rat genome database

More...
RGDi
1584052 Dnhd1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A0A0G2JZ61

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000051291 Expressed in 9 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0G2JZ61 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0G2JZ61

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1028 – 1475DHC_N2InterPro annotationAdd BLAST448
Domaini1659 – 2012AAA_6InterPro annotationAdd BLAST354
Domaini2229 – 2355Dynein_AAA_lidInterPro annotationAdd BLAST127
Domaini2707 – 2962AAA_8InterPro annotationAdd BLAST256
Domaini3071 – 3306MTInterPro annotationAdd BLAST236
Domaini3924 – 4069Dynein_heavyInterPro annotationAdd BLAST146
Domaini4303 – 4585Dynein_CInterPro annotationAdd BLAST283

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 26DisorderedSequence analysisAdd BLAST26
Regioni284 – 315DisorderedSequence analysisAdd BLAST32
Regioni3408 – 3500DisorderedSequence analysisAdd BLAST93
Regioni4443 – 4465DisorderedSequence analysisAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili734 – 754Sequence analysisAdd BLAST21
Coiled coili820 – 840Sequence analysisAdd BLAST21
Coiled coili1888 – 1908Sequence analysisAdd BLAST21
Coiled coili3029 – 3063Sequence analysisAdd BLAST35
Coiled coili3625 – 3645Sequence analysisAdd BLAST21
Coiled coili4272 – 4292Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 16Pro-richSequence analysisAdd BLAST16
Compositional biasi3415 – 3431PolyampholyteSequence analysisAdd BLAST17
Compositional biasi3432 – 3451AcidicSequence analysisAdd BLAST20
Compositional biasi3483 – 3500PolarSequence analysisAdd BLAST18
Compositional biasi4447 – 4463PolarSequence analysisAdd BLAST17

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155523

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.140.100, 1 hit
3.20.180.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035699 AAA_6
IPR026983 DHC_fam
IPR042228 Dynein_2_C
IPR042222 Dynein_2_N
IPR041466 Dynein_AAA5_ext
IPR041228 Dynein_C
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_D6_P-loop
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676 PTHR10676, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF08393 DHC_N2, 1 hit
PF17852 Dynein_AAA_lid, 1 hit
PF18199 Dynein_C, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0G2JZ61-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPHPQSSPP TLPMPSVSCR PGQTQKPKDW NWHLDPELWA RSVRQQLNTC
60 70 80 90 100
LRFILEERKV PLSPEIPWFD TLQSGLAGCS CSGQEHSWDC QEKQEHLKAV
110 120 130 140 150
VESEQRNMLE LLLSELKSLF SAVLQDGSCE AWHYLHAVLG LLPPYREMLA
160 170 180 190 200
GQLELLPFLE QLYCWAPKVQ AWLQLDLLDA IDKAFPPDSS LLHSSSHVDC
210 220 230 240 250
SPWMKRFHRG PPCSACPFVK ARWDQQQKKE LATWLRPLTL PELQHCLGIV
260 270 280 290 300
GAEVALEETP WLDSLSLLPL ALATDIPVQY ESSDIGHAEP APAGRKPQLA
310 320 330 340 350
SEAPEKALKR KSPRTSILRS QVKSLLKGDW SQKKIHFLYL NVASDRHFNP
360 370 380 390 400
YKLVVVPPNK VNPEHYIFSP FGILHIHPVE GSETMSLATW HRDTALWHEL
410 420 430 440 450
QRIPFFKNCL LRKALTCWKK NVRFRGLHRI QTFLKTHLLL AIPHFGAGML
460 470 480 490 500
HINRLLQEFR SVSWLPKEPD KSYVLRDLKK AIAKENHRAL RVLCHFLNLC
510 520 530 540 550
ASILQLIHED TYQMQQGLQE RVQNWNRIRK SQGSIYLQRT LCRHLEKKLK
560 570 580 590 600
QAETWLSKLG MFARLIDYMI CQNLVSILED EITSFIANNL QAPRQNPFLV
610 620 630 640 650
SQLVFDDNGQ LSPMPRVESI IQSLIKSLQS IKTSALKVMQ STDLRTSREP
660 670 680 690 700
LYSEDNKDQD SNTEFPMPKF HGKSSDAVRL FCGPNVGYVW PWKSHAITNV
710 720 730 740 750
LEVRGHRLRG QYLHPNYDHV QEDLDKNAGI QQALAVQQAL LEDMRQEVQE
760 770 780 790 800
FCNKQQWVED IYEFLKAWNS QKLEDLRGSP ISDYVKLVRK LKNWQERVSN
810 820 830 840 850
MPVELLTKTK LLLLSGRDVQ EELESKLNNL RKNILEQVKN ECWSRNQQLM
860 870 880 890 900
KKLTEFLRVF QTINLDIHAI AQCSQKLNEA NEQYCHLEEQ VEYVRSLHDL
910 920 930 940 950
IRNHCVLFIS ENETLDIALL DLWEAFQFER SQVSEFLLSK RHAIVPKLQQ
960 970 980 990 1000
LMAAALAELE GLLVKALSGP FMDPSQEQRS TEQQLGALEN QFLNTLSNFN
1010 1020 1030 1040 1050
ALCYAYRSFT GHKTTMSPPA SGNRPIVLQQ RIWRLYRIIH ENFSEWKCVA
1060 1070 1080 1090 1100
FSKFNLSMAR EKTNAWLTEA ARLGTALGQQ SPVLQRCMRM LEEFRAYLPL
1110 1120 1130 1140 1150
LIKLGSLELQ DVNTQSLLRA LGLGGLQSLD LLTLGRLLNC PLLEFADRIN
1160 1170 1180 1190 1200
QVWQRDKERI HAQEILQQMQ QYWEGRQLRL LNFILQVPYR PPTSERSKRP
1210 1220 1230 1240 1250
ALRSPQWELV GKDSGTFLLS DYSSLQDAIQ NSLQALFKIL AIQKSGQLHK
1260 1270 1280 1290 1300
IALEWVTIMY DLGALLEVWV SFQQKWIFLN KVLHEMEIEF PAAELNARFK
1310 1320 1330 1340 1350
VMDDQYRTLM RISVADPMVL SLIVPNTKRS PYFQGQHLQH LLKVGSVELE
1360 1370 1380 1390 1400
AIIMGLEDVL YGVRANFPRL FFLSDSELVA LLASPLDTSE AKPWAQRCFP
1410 1420 1430 1440 1450
YIKAVNFRSK STNKENNDKD SKSSIETVET ISVLGACGEE VKLQEPLPLY
1460 1470 1480 1490 1500
PDLPKWLASL ETCLRLVVVN LLQSCVATRL AQGPSLIKAL KAMPQQRQMS
1510 1520 1530 1540 1550
TQLYVQHWLD AVQVFPWQCI LVAEEIVWRA EMEEALLESK TMRLSSVHVR
1560 1570 1580 1590 1600
NLEVLVQFIR SQRSSQGEQP LPSVRQTSLF SSLLVKAVTH RDIAQLLEKN
1610 1620 1630 1640 1650
QVSDLTDFHW VRQIKYHLGS SHLNLKSPLQ CLTTTASTEE PSVSPAACWI
1660 1670 1680 1690 1700
DVLGRSFLYN YEYMGPKLGP LPSLMHERQV FILLLALNEV AYGAVLGRDG
1710 1720 1730 1740 1750
LGKAETVNSL AWALGRQLVI MPCLPQIEFR CLSNYLNGAL QCGAWLLLEN
1760 1770 1780 1790 1800
VHQLPSGLLS ALGQRLDELH HLYAPLYQKA SKNISTINPT KHLLLGAGFF
1810 1820 1830 1840 1850
EKHQVSVRLG FGCFLTFHSL SPDVPANLHL LLRPVALAFP DLQRVAELQL
1860 1870 1880 1890 1900
LGAGVRDASR MATRLSKLFS LERELVSGTL PSRLPLLKQV LENTIETLNA
1910 1920 1930 1940 1950
SEENKSQQPH NLAAAEEAAL LRALLHSPLF TILDGLRLQK LQELLCGIFP
1960 1970 1980 1990 2000
NASHVLAEPV CHRLMKSVVV EELQQLGLFP TLNTLTSLEQ LSEALSKASG
2010 2020 2030 2040 2050
ILLLGTAGSG KSTCWKSLFK IQNRLAAMEH TSTKGFQSVE TVHLYPSVLT
2060 2070 2080 2090 2100
SQEYLGWSEG SSWRYGIFTK LLHAAPYCKT VGSEEKSERF TGIQQWIICD
2110 2120 2130 2140 2150
GAPNHAWLDS ITCLLADPPQ LSLPNGQQIA RPLGTFFLIE VAEAAGMSPT
2160 2170 2180 2190 2200
VLGRCALVWC CGEQTWQSML SVLITSLPHE YHLQQETIVQ FNHLAEVLVP
2210 2220 2230 2240 2250
SVFRFLTRIG ASSQLQVHGH QAVCPGVAEV TSLIRILRAL LDPHLHLFEE
2260 2270 2280 2290 2300
EKPHTKEDFS GTDLVTQNFI SSKSKAQSDR ISVYKKERRH LLAISSFLFA
2310 2320 2330 2340 2350
IIWGFGAHLS SRHWPLFDDF MRKAISSLPN YPEPPPSALV FDLHINLEDG
2360 2370 2380 2390 2400
TLVPFTGQYL STHVKRSLGS FQPSSQVEQL LYVVDLLLSN GQPVLLAGEI
2410 2420 2430 2440 2450
ATGKSAFVEV LVEPNHPTIH RPINPALNSA HLRNLLSRAV HGQTQAGSFV
2460 2470 2480 2490 2500
GPHQDSKGSI LFLMEDLHLA AFDPEKSCQP VLETLRQAME GTIYSHNTLE
2510 2520 2530 2540 2550
LQTLQPTVNF LATATVPGYS ERPLCPRLYR LFTVLALNSM TQDTLLSRHV
2560 2570 2580 2590 2600
PSIQAWLERF PSVEREHTLA RALVRASVEA WEAVCNCFMP SPLHPHYRFS
2610 2620 2630 2640 2650
PHSVSHILGS LQLLPTRMGS RGFVDSFHHQ EHLRRVSGLR GTRLTIMMSM
2660 2670 2680 2690 2700
RVMENPSDLV FSLELTLGSN FESPNLYLER QWENLEKQLA ASAVQLKMNS
2710 2720 2730 2740 2750
DFAQCHVMVQ HVARLVRVLA RPRQHGLLLS EFRGTGRNTA IILASNICQA
2760 2770 2780 2790 2800
RLFHLPFESE EAVFQCLRDA SWHAGVLNQS VALLVPDQVN VATFCQLLAL
2810 2820 2830 2840 2850
ATSGSFPDQY TEADLDNIEE HLPKENLVNK YSIKKDTVLN RFYQQVCSNL
2860 2870 2880 2890 2900
HMFFLMEDDQ VQKQLPSTLF LSLLQLTIAS VDRYEPWDQA SLVRVAQFRL
2910 2920 2930 2940 2950
ENDQSLPLDD GSLKCPDFKI LIPNVANIMA RIHGSSAYYH QHMCPALPLV
2960 2970 2980 2990 3000
TPRTFQDFLD MFLQQQQQMV LQMRMRARRI QSALKTLRLL VERHSTQTSM
3010 3020 3030 3040 3050
LTDLEKQLKG SYKNVGMYQG QLEQCKILYK QKMAECQHLE SLIENLTRQH
3060 3070 3080 3090 3100
DALKAQQEAF LEQMGKAFVG PLSQLRVADF EEIRSYRAPP ESVVKVTDAL
3110 3120 3130 3140 3150
CDLFHHETGW SSAKQLLCTE DFYQELVFFP KEKLMDSELA KLSQALRAPG
3160 3170 3180 3190 3200
MSDASLRSVS IPAANLAVWL RAVLRYGLAQ RRGLPTGLLL RQVDATLARE
3210 3220 3230 3240 3250
QARLGQFQFQ AHDLLQQTQF LTKKLEDAQL SHNHVVETLN QAQCGHFHRW
3260 3270 3280 3290 3300
PMKSALLTPM HMWTTQLQKL QEQAKTVFGD ALLCSAAIVY LGPFPPQRRQ
3310 3320 3330 3340 3350
ELLEKWLSLC QGFEEALDPD DVAQALRQKS VRVSKNPLLP TRTPFRILTL
3360 3370 3380 3390 3400
LSCGSEQHQW DRDLKPQAKS ARLLGLLLRS HIHFSSSRWP LLLDPSNQAI
3410 3420 3430 3440 3450
IWLNPLPPKQ NKWLEQPPKE SRAKYHVTNQ DSEDETEDEL ESENNEDEDE
3460 3470 3480 3490 3500
VSEQREEHKT EENESEEENK QEEQETEKEN EAESTSSGSS SSPPSETQCL
3510 3520 3530 3540 3550
PSYLTVLSGT DPELGPQLLE AAANGLPVLL TNMELSLGCQ ELQWLLSKKN
3560 3570 3580 3590 3600
LIPPYVQPGF CLFLSTTFPI HALDRVLGYE LLKGLNVLDL GLNMEILEEQ
3610 3620 3630 3640 3650
MLHEILCRER PELETRWQDL KVRAAENYEA MKADEEQLLV ILLRQNKMRQ
3660 3670 3680 3690 3700
KPSRFLREMV RTQAKICQLN AQGEELDEQK LEVAALWAPY RQVAYHGMAM
3710 3720 3730 3740 3750
VEALSSLQNL LPFFCMKSEN WLAVIRRAID SMKSCDSYHG EDLPSHLLRM
3760 3770 3780 3790 3800
KIHLARQLLI NTVVALGLIQ TPLVGAFGAL AMLQVTKKTP KLERLALWPG
3810 3820 3830 3840 3850
LLASPSSGHN IQIPGVTRPA WLSSRAWEEC GALELLSPFA GLRASLASHS
3860 3870 3880 3890 3900
DVWQDYLSLS STVLGPAPGP NSEPLSLFQK LILWRVLRPD CLVGALADLT
3910 3920 3930 3940 3950
TSLLGRPLDE DLDAPTMIFD HIQPTQPILI LLPPPGHPTA TLHPVTVIRK
3960 3970 3980 3990 4000
LAASEKPQKR LHVIALGSED WDPVSTVVNT LSQAMLQGHW LVLDNCHLMP
4010 4020 4030 4040 4050
FWPRELLQPL QGLLDGAKVV SDSELIAEPE SRTVATVHRD FRLWLIASTE
4060 4070 4080 4090 4100
ASTSLPGVLT QHSMPVFWNQ SLELGRILID SVDSQQELST QSFTQTFPLF
4110 4120 4130 4140 4150
FLYGLLVHRQ LYGLKLQAHR GRWSQVTLTR VLQIQEQLWA SLSNPSAALL
4160 4170 4180 4190 4200
ELAASVLYGG PLRDLEDRET LVSLTGACLN PRNMNWVQPH TPQYLLATLM
4210 4220 4230 4240 4250
PSPELGELDA RTDCKAQMHL LPTPSEPRTC GLNEGPQAWL LRRQSRALLS
4260 4270 4280 4290 4300
ALRQCSSTWV PTVCGGIVQR KERRLRQRLV QAKKRLVALQ ALLTNNRYRS
4310 4320 4330 4340 4350
GQCVTPWAVL GPNARPPLEG FLETEVLELK QLVGMLLRDL DCLLQQLKGK
4360 4370 4380 4390 4400
TPCTSSRCAE VAQALWAGRL PQPWRSHAPA GPQLPWLWLR QLSRRGHLLI
4410 4420 4430 4440 4450
QYLDSGISEN ANGPERIFHL SAFRHPRRLL LALRWEAVLE NSGHSPKLPG
4460 4470 4480 4490 4500
HQGSGSGNLP PRRQELNNHP LHIWVENGPN PKVPKMGLLL IGLQLQHAAW
4510 4520 4530 4540 4550
DQTDGALKDS FSSQPCPLPP VSVSTQSRGA KDASVSAGLG IYSCPLYMTG
4560 4570 4580 4590
PLGTTKLHSK NILMRLPLPT RLSPDTCIQR RVHVCSPTLT
Length:4,590
Mass (Da):519,608
Last modified:July 22, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i633A10CCF657D66C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A096MJU2A0A096MJU2_RAT
Dynein heavy chain domain 1
Dnhd1
4,770Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07071958 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000081667; ENSRNOP00000070922; ENSRNOG00000051291

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07071958 Genomic DNA No translation available.

3D structure databases

SMRiA0A0G2JZ61
ModBaseiSearch...

Proteomic databases

PaxDbiA0A0G2JZ61

Genome annotation databases

EnsembliENSRNOT00000081667; ENSRNOP00000070922; ENSRNOG00000051291

Organism-specific databases

RGDi1584052 Dnhd1

Phylogenomic databases

GeneTreeiENSGT00940000155523

Gene expression databases

BgeeiENSRNOG00000051291 Expressed in 9 organ(s), highest expression level in testis
ExpressionAtlasiA0A0G2JZ61 baseline and differential

Family and domain databases

Gene3Di1.20.140.100, 1 hit
3.20.180.20, 1 hit
InterProiView protein in InterPro
IPR035699 AAA_6
IPR026983 DHC_fam
IPR042228 Dynein_2_C
IPR042222 Dynein_2_N
IPR041466 Dynein_AAA5_ext
IPR041228 Dynein_C
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_D6_P-loop
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 2 hits
PfamiView protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF08393 DHC_N2, 1 hit
PF17852 Dynein_AAA_lid, 1 hit
PF18199 Dynein_C, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0G2JZ61_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0G2JZ61
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: October 16, 2019
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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