Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

NLR family, pyrin domain-containing 12

Gene

Nlrp12

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
NLR family, pyrin domain-containing 12Imported
Gene namesi
Name:Nlrp12Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1309415 Nlrp12

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiA0A0G2JW23

Expressioni

Gene expression databases

BgeeiENSRNOG00000060745

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000047433

Structurei

3D structure databases

ProteinModelPortaliA0A0G2JW23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 95PyrinInterPro annotationAdd BLAST95
Domaini211 – 528NACHTInterPro annotationAdd BLAST318

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00900000140813
KOiK20865
OMAiCLCWEEK
PhylomeDBiA0A0G2JW23

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR029495 NACHT-assoc
IPR007111 NACHT_NTPase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF14484 FISNA, 1 hit
PF13516 LRR_6, 5 hits
PF05729 NACHT, 1 hit
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01288 FISNA, 1 hit
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS50824 DAPIN, 1 hit
PS50837 NACHT, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0G2JW23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPATAKDAL HRLSTYLEEL EAGELKKFKL YLGIAEELGQ DKIPRGRMEM
60 70 80 90 100
AGPLEMAQLM VAHMGTKEAW LLALSTFERI HRKDLWERGQ GEDLVRVTPS
110 120 130 140 150
NGLCSLESQS TCLSDVSPDA PRKDPQITYK DYVRRKFRLM EDRNARLGEC
160 170 180 190 200
VNLSHRYTRL LLVKEHSNPI WAQQKLLETG WEHSRTRGHQ ASPIQMETLF
210 220 230 240 250
EPDEERPEPP RTVVLQGAAG MGKSMLTHKV MLDWADGRLF QDQFDYVFYI
260 270 280 290 300
SCRELNRSHT QCSVHDLLSS CWPEHGAPLE DLIRAPDRLL FIIDGFHELH
310 320 330 340 350
PSFHDVQGPW CHCWEEKRPT ELLLGSLIRR LLLPQLSLLI TTRPCALEKL
360 370 380 390 400
HGLLEHPRHV EILGFSEAER EEYFYRYFHN TGQASQVFSF MRDYEPLFTM
410 420 430 440 450
CFVPMVSWVV CTCLKQQLES GELLRQTSRT TTAVYMFYLL SLMQPKPGTP
460 470 480 490 500
TFKVPANQRG LVSLAAEGLW NQKILFEEED LGKHGLDGAE VSTFLNVNIF
510 520 530 540 550
QKGIKCEKFY SFIHLSFQEF FTAMYCALHG REAVRRALAE YGFSERNFLA
560 570 580 590 600
HTVRFLFGLL NEEMRCYLER NLGWTISPQV KEEALAWIQN KARSEGSTLQ
610 620 630 640 650
HGSLELLSCL YEIQEEDFIQ QALSHFQVVV VRNLSTKMEH VVCSFCARYC
660 670 680 690 700
RGTEVLHLYG SAYSTGAEDG PPEPPGAQTQ STHSQERNIL PDIYSAYLSA
710 720 730 740 750
TICTNSNLIE LALYRNALGS QGVRLLCQGL RHANCKLQNL RLKRCHISGS
760 770 780 790 800
ACQDLAAAII ANRNLIRLDL SGNSIGVLGL ELLCEGLQHP MCRLQMIQLR
810 820 830 840 850
KCLLEAAAGR ALASVLSNNS HLVELDLTGN PLEDLGLKLL CQGLRHPVCR
860 870 880 890 900
LRTLWLKICH LGQASCEDLA STLKMNQSLM ELDLGLNDLG DSGALLLCEG
910 920 930 940 950
LRHPDCKLQT LRLGICRLGS DACAGVASVL QVNTCLRELD LSFNDLGDRG
960 970 980 990 1000
LWLLGEGLRH QTCRLQKLWL DSCGLTSKAC EDLSSVLGIS QTLNELYLTN
1010 1020 1030 1040 1050
NALGDTGVRL LCKRLRHPGC KLRVLWLFGM DLNKVTHRRM AALRVTKPYL

DIGC
Length:1,054
Mass (Da):119,267
Last modified:July 22, 2015 - v1
Checksum:iFDC7B54EAEB18D87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106193 Genomic DNA No translation available.
RefSeqiNP_001162613.1, NM_001169142.1
XP_008756975.1, XM_008758753.2
UniGeneiRn.108865

Genome annotation databases

EnsembliENSRNOT00000086331; ENSRNOP00000069711; ENSRNOG00000060745
GeneIDi292541
KEGGirno:292541

Similar proteinsi

Entry informationi

Entry nameiA0A0G2JW23_RAT
AccessioniPrimary (citable) accession number: A0A0G2JW23
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: June 20, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health