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Entry version 30 (05 Jun 2019)
Sequence version 1 (22 Jul 2015)
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Protein
Submitted name:

Myosin XVA

Gene

Myo15a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi1300 – 1307ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myosin XVAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Myo15aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Rat genome database

More...
RGDi
1561873 Myo15a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000059219 Expressed in 4 organ(s), highest expression level in skeletal muscle tissue

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0G2JTE7 differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0G2JTE7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1207 – 1884Myosin motorInterPro annotationAdd BLAST678
Domaini2032 – 2178MyTH4InterPro annotationAdd BLAST147
Domaini2827 – 2913SH3InterPro annotationAdd BLAST87
Domaini3010 – 3164MyTH4InterPro annotationAdd BLAST155
Domaini3169 – 3480FERMInterPro annotationAdd BLAST312

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 43DisorderedSequence analysisAdd BLAST43
Regioni569 – 701DisorderedSequence analysisAdd BLAST133
Regioni737 – 1035DisorderedSequence analysisAdd BLAST299
Regioni1105 – 1131DisorderedSequence analysisAdd BLAST27
Regioni1149 – 1210DisorderedSequence analysisAdd BLAST62
Regioni1763 – 1785Actin-bindingPROSITE-ProRule annotationAdd BLAST23
Regioni2376 – 2402DisorderedSequence analysisAdd BLAST27
Regioni2440 – 2491DisorderedSequence analysisAdd BLAST52
Regioni2941 – 2966DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 27PolyampholyteSequence analysisAdd BLAST27
Compositional biasi617 – 633PolarSequence analysisAdd BLAST17
Compositional biasi653 – 680Pro-richSequence analysisAdd BLAST28
Compositional biasi796 – 810Pro-richSequence analysisAdd BLAST15
Compositional biasi831 – 846Pro-richSequence analysisAdd BLAST16
Compositional biasi1016 – 1030PolarSequence analysisAdd BLAST15
Compositional biasi1177 – 1194PolarSequence analysisAdd BLAST18
Compositional biasi1195 – 1210PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2942 – 2956PolyampholyteSequence analysisAdd BLAST15

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotation

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155335

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473 FERM_B-lobe, 1 hit
cd13201 FERM_C_MyoXV, 1 hit
cd01387 MYSc_Myo15, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.530, 2 hits
2.30.29.30, 2 hits
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR035487 MYO15A
IPR001609 Myosin_head_motor_dom
IPR041795 MyoXV_FERM_C
IPR036057 MYSc_Myo15
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

The PANTHER Classification System

More...
PANTHERi
PTHR22692:SF21 PTHR22692:SF21, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00373 FERM_M, 1 hit
PF00612 IQ, 2 hits
PF00063 Myosin_head, 1 hit
PF00784 MyTH4, 2 hits
PF07653 SH3_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00193 MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00015 IQ, 3 hits
SM00242 MYSc, 1 hit
SM00139 MyTH4, 2 hits
SM00326 SH3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47031 SSF47031, 1 hit
SSF50044 SSF50044, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50057 FERM_3, 1 hit
PS50096 IQ, 2 hits
PS51456 MYOSIN_MOTOR, 1 hit
PS51016 MYTH4, 2 hits
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0G2JTE7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EDEEKKAKKG KKGKKAPEPE KPKRSLKGTS RLFMGFRDRT PKISKKGQFR
60 70 80 90 100
SASAFFWGLH TGPQKTKRKK KARTVLKSTS KLMTQMRVGK KKRAMKGKKP
110 120 130 140 150
SFMVIRFPGR RGYGRLRPRA QSLSKASTAI NWLTKKFLLK KAEESGSEQA
160 170 180 190 200
TLDAWLQRSS SRVGSRKLPF PSGAEILRHG GRLRRFPRSH SIYSSGEPVG
210 220 230 240 250
FLPFEDEAPF RHAGSRKSLY GLEGFQDLGE YYDYHREGDD YYDQQSLYHY
260 270 280 290 300
EEQEPYLAGF GGYSPAWPPY DDYGYPSGDP YNYYHPDYYG DTLYPAYGYG
310 320 330 340 350
YGYGYDDLEP PYAPPSGYSS PYSYHDSFED EAYPYSYYLD PYATHHMPYP
360 370 380 390 400
PYDFPHDTPY DIPYFDPYGV PYAEGIYGGG AEAIYPPGVP YVYPEEPAFM
410 420 430 440 450
YPWVPPPIMS PHNPYAHPMD DIAELEEPEE IGRERQSTSF RLPSAAFFEQ
460 470 480 490 500
QGMDKPARSK LSLIRKFRLF PRPQVKLFGK EKLEVPLPPS LDIPLPLGDA
510 520 530 540 550
EGEEEEEEMP PVPTMPYTHP YWSFLTPRQR NLQRALSAFG ARQGLGFGPE
560 570 580 590 600
FGPPTPRPAT SLARFLKKTL SEKKPIPRLR GSQKARGGRP PVREAAYKRF
610 620 630 640 650
GYKLAGMDPD RPNTPIVLRR SQPQARNNNN SHGPPSPRPA PRTLTHWSAL
660 670 680 690 700
ISPPMPGPSP SPASPLTPPF SPPLSRPPRL ASPYSSPYGS LRQHPPPWAA
710 720 730 740 750
PAHVPFPLQA NWWGFAEPPG TSPEVAPDLM AFPVPRPSFR ASRSRGAAYG
760 770 780 790 800
FPRPSLIGSR RRPHLPSPQP SLRSLPGQGY HSPLGHLSPQ LSLRRGPFQP
810 820 830 840 850
PFPPPPRRPQ SLRETFSLHR TSGRLGPPRS PVLGSPRPPS PPPLLKHPRH
860 870 880 890 900
RSLNLPSRLP RTWRRLSEPP TRAVKPWIHR AYHPPPSAGP WGATAGSLEH
910 920 930 940 950
QENQREPEDS ETPWTVPPLA PSWDVDMATT QRPPSPWPEG VGSLRGFSRP
960 970 980 990 1000
PPVPENPLLE HTSPSCEPRP EDQASNLTGI FLGQHHDPGP GQLTKSANPS
1010 1020 1030 1040 1050
LENPEEVVIS EDPQPSAEPE TLNTPPNKTV VSERKALRPS ASYPLVTCKQ
1060 1070 1080 1090 1100
SRATWPQWHR WKTVSRTPAP LAPTRAPGSL LKAGKQLRDK PGRFAVVMPQ
1110 1120 1130 1140 1150
VRGLSSFQQK GSAPLQPPEH SDQDPEHGPA TQACSLRWPR LWSPADTHSP
1160 1170 1180 1190 1200
WPRIHTLSSP SPLRGHGGDC QSPKDLWKKT GSRSWQNKMH SIRNLPSVRS
1210 1220 1230 1240 1250
REQHREDGVE DMTQLEDLQE TTVLTNLKTR FERNLIYTYI GSILVSVNPY
1260 1270 1280 1290 1300
RMFAIYGPEQ VQQYSGRALG ENPPHLFAIA NLAFAKMLDA KQNQCVIISG
1310 1320 1330 1340 1350
ESGSGKTEAT KLLLRCLAAM NQRRDVMQQI KILEATPLLE AFGNAKTVRN
1360 1370 1380 1390 1400
DNSSRFGKFV EIFLEGGVIC GAITSQYLLE KSRIVFQAKN ERNYHIFYEL
1410 1420 1430 1440 1450
LAGLPAQLRQ AFSLQEAETY YYLNQGGNCE IAGKSDADDF RRLLAAMEVL
1460 1470 1480 1490 1500
GFTSEDQDSI FRILASILHL GNVYFEKHET DAQEVASVVS AREIQAVAEL
1510 1520 1530 1540 1550
LQVSPEGLQK AITFKVTETI REKIFTPLTV ESAVDARDAI AKVLYALLFG
1560 1570 1580 1590 1600
WLITRVNALV SPKQDTLSIA ILDIYGFEDL SFNSFEQLCI NYANENLQYL
1610 1620 1630 1640 1650
FNKIVFQEEQ EEYIREQMDW REIAFADNQP CINLISLKPY GILRILDDQC
1660 1670 1680 1690 1700
CFPQATDHTF LQKCHYHHGA NPLYCKPKMP LPEFTIKHYA GKVTYQVHKF
1710 1720 1730 1740 1750
LDKNHDQVRQ DVLDLFVHSR TRVVAHLFSS HAAQTAPPRL GKSSSITRLY
1760 1770 1780 1790 1800
KAHTVAAKFQ QSLLDLVEKM ERCNPLFVRC LKPNHKKEPG LFEPDVMMAQ
1810 1820 1830 1840 1850
LRYSGVLETV RIRKEGFPVR LPFQVFIDRY RCLVALKLNV PADGDMCVSL
1860 1870 1880 1890 1900
LSRLCTVTPD MYRVGVSKLF LKEHLHQLLE SMRERVLNRA ALTLQRYLRG
1910 1920 1930 1940 1950
FFTQRRFRSL RQKIILLQSR ARGFLARQRY QQMRQSLLKF RSLVHTYVNR
1960 1970 1980 1990 2000
RRYLKELSKR EVVPVRHLEV PAEVAGLLQA AAGLKPSSVP QVAIVRAPRL
2010 2020 2030 2040 2050
QAEPCVTLPL DINNYPMAKF IRCHFKEPSF GMLTVPLKMP LTQMLVEHHA
2060 2070 2080 2090 2100
EAISVFKLIL RFMGDPHLHG TQEMILGNYI VHQGLVEPAL RDEILAQLAN
2110 2120 2130 2140 2150
QVWRNPNAYN AKRGWLLLAA CLSGFAPSSH LDKFLLKFVS DYGQNGFQAV
2160 2170 2180 2190 2200
CQHRLLQAMG SGAARTFPPT QLEWTAIQEK ASMALDVSCF NGDQFSCPVH
2210 2220 2230 2240 2250
PWSTGEAVAG DILKHRGLAD GWRGWTVAMK NGVQWAELAG HDYVLDLVSD
2260 2270 2280 2290 2300
LELLRDFPRQ KSYFIVGAEG PLAGRGDTRG VFGNCWDSDE DTPTRPQPQD
2310 2320 2330 2340 2350
HVAKMPDFDG YCSHKEDGTN GETAAQRWAS NRQAVDNTGE PAVPPRELDG
2360 2370 2380 2390 2400
YLDSLFDPVL ACGDVDLEKP TAIAYRMKGG GQPGSSASED TPRRLPEPKL
2410 2420 2430 2440 2450
KPIPGLDAST LALQQAFIHR QAVLLAREMT LQALALQQQP LSATSRPQLP
2460 2470 2480 2490 2500
ERPLPPEARP KTVGTGPPAK PVLVRPTPQS LAPGSVAKSP KIPSKPVAAP
2510 2520 2530 2540 2550
ILARDWTAPE SISSSPELVR YSTLNSEHFP QPTQQIKSII KQYKQPPWAG
2560 2570 2580 2590 2600
HPEARRTDGG KVFRRPPDPH EEALMILKGQ KTQLAVVPGT QVSREAVALV
2610 2620 2630 2640 2650
KPVTSAPRPC MGAAPVQPSR SLEPPEDPVQ TQLHRLVNPN FYGYQDAPWR
2660 2670 2680 2690 2700
IFLRKEVFYP KDNYSHPVQL DLLFRQILHD TLSEACLRIS EDERLQMKAL
2710 2720 2730 2740 2750
FAQNQLDTQR PLVTESVKRA AINMARDSWE IYFSRLFPAM GSVGTGVQIL
2760 2770 2780 2790 2800
AVSHTGVKLL RMAKGNREAS RRLRVLCAYS FADILFVTMP SQNMLEFNLT
2810 2820 2830 2840 2850
NEKVILFSAR ARQVKTLVDT FILELKKDSD YVVAVRNFLS EDPELLSFHK
2860 2870 2880 2890 2900
GDIIHLQSLE PPRIGYSAGC VVRKKLVYLE ELRRRGPDFG WRFGAVHGRV
2910 2920 2930 2940 2950
GRFPSELVQP AAAPDFLQLP AEPGRGRAAA VAAAVASAAA AREVGRRREG
2960 2970 2980 2990 3000
PPVRARSADS GEDSVALPPS TMLEFAQKYF RDPRRRPRDG LKLKSKEDRE
3010 3020 3030 3040 3050
SKTLEDMLCF TKVPIQESLI ELSDSNLNKM AVDMFVAVMR FMGDAPLKGQ
3060 3070 3080 3090 3100
NELDVLCTLL KFCGDHEVMR DECYCQIVKQ ITDNTSSKQD SCQRGWRLLY
3110 3120 3130 3140 3150
ILAAYYSCSE VFYPYLIRFL QHVSWTPGLP FQGIAKACEQ NLQKTLRFGG
3160 3170 3180 3190 3200
RLEFPSSMEL RAMLAGRSSK RQLFLLPGGL ERHLKIKTCT VALDVIEGLC
3210 3220 3230 3240 3250
SEMALTRPEA FDEYVIFVVT NRGQHVCPLS CQAYILDVAS GMEQVDGGYT
3260 3270 3280 3290 3300
LWFRRVLWDQ PLKFENELYV TMHYNQVLPD YLKGLFSSVP ASQPTEQQLQ
3310 3320 3330 3340 3350
QVSKLASLQH RAKDHFYLPS VREVQEYIPA QLYHTTAGDT WLNLVSQHRQ
3360 3370 3380 3390 3400
QTQALSPHQA RAQFLGLLSA FPLFGSSFFF IQSCSNVLVP APCILAVNHN
3410 3420 3430 3440 3450
GLNFLSTKTH ELIVKIPLKE IQSTWTQQPT ANSSYPYVEI SLGDVAAQRT
3460 3470 3480 3490
MQLQLEQGLE LCRVVAVHVE SMLSAREERL TLPPSEITLL
Length:3,490
Mass (Da):392,773
Last modified:July 22, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92D6EB462F09A8C2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2K1F7A0A0G2K1F7_RAT
Myosin XVA
Myo15a
3,508Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC129460 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000079133; ENSRNOP00000068681; ENSRNOG00000059219

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129460 Genomic DNA No translation available.

3D structure databases

SMRiA0A0G2JTE7
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000079133; ENSRNOP00000068681; ENSRNOG00000059219

Organism-specific databases

RGDi1561873 Myo15a

Phylogenomic databases

GeneTreeiENSGT00940000155335

Gene expression databases

BgeeiENSRNOG00000059219 Expressed in 4 organ(s), highest expression level in skeletal muscle tissue
ExpressionAtlasiA0A0G2JTE7 differential

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
cd13201 FERM_C_MyoXV, 1 hit
cd01387 MYSc_Myo15, 1 hit
Gene3Di1.25.40.530, 2 hits
2.30.29.30, 2 hits
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR035487 MYO15A
IPR001609 Myosin_head_motor_dom
IPR041795 MyoXV_FERM_C
IPR036057 MYSc_Myo15
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR22692:SF21 PTHR22692:SF21, 1 hit
PfamiView protein in Pfam
PF00373 FERM_M, 1 hit
PF00612 IQ, 2 hits
PF00063 Myosin_head, 1 hit
PF00784 MyTH4, 2 hits
PF07653 SH3_2, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00015 IQ, 3 hits
SM00242 MYSc, 1 hit
SM00139 MyTH4, 2 hits
SM00326 SH3, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF50044 SSF50044, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50057 FERM_3, 1 hit
PS50096 IQ, 2 hits
PS51456 MYOSIN_MOTOR, 1 hit
PS51016 MYTH4, 2 hits
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0G2JTE7_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0G2JTE7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: June 5, 2019
This is version 30 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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