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Protein
Submitted name:

Killer cell immunoglobulin-like receptor 2DL4

Gene

KIR2DL4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Killer cell immunoglobulin-like receptor 2DL4Imported
Gene namesi
Name:KIR2DL4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:6332 KIR2DL4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei227 – 245HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500254628224 – 360Sequence analysisAdd BLAST337

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 120IGInterPro annotationAdd BLAST85
Domaini131 – 218IGInterPro annotationAdd BLAST88

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013151 Immunoglobulin
PfamiView protein in Pfam
PF00047 ig, 2 hits
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 30 potential isoforms that are computationally mapped.iShow all

A0A0G2JMV5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSMSPTVIIL ACLGFFLDQS VWAHVGGQDK PFCSAWPSAV VPQGGHVTLR
60 70 80 90 100
CHYRRGFNIF TLYKKDGVPV PELYNRIFWN SFLISPVTPA HAGTYRCRGF
110 120 130 140 150
HPHSPTEWSA PSNPLVIMVT GLYEKPSLTA RLGPTVRAGE NVTLSCSSQS
160 170 180 190 200
SFDIYHLSRE GEAHELRLPA VPSINGTFQA DFPLGPATHG ETYRCFGSFH
210 220 230 240 250
GSPYEWSDPS DPLPVSVTGI ARHLHAVIRY SVAIILFTIL PFFLLHRWCS
260 270 280 290 300
KKKNAAVMNQ EPAGHRTVNR EDSDEQDPQE VTYAQLDHCI FTQRKITGPS
310 320 330 340 350
QRSKRPSTDT SVCIELPNAE PRALSPAHEH HSQALMGSSR ETTALSQTQL
360
ASSNVPAAGI
Length:360
Mass (Da):39,714
Last modified:July 22, 2015 - v1
Checksum:i1F0207C1BB11ECD0
GO

Computationally mapped potential isoform sequencesi

There are 30 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99706KI2L4_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4 CD158D, KIR103AS
377Annotation score:
Q86U48Q86U48_HUMAN
KIR2DL4
KIR2DL4 KIR-2DL4
377Annotation score:
A0A0B4J1S6A0A0B4J1S6_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
273Annotation score:
A8MT18A8MT18_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
398Annotation score:
K7RE46K7RE46_HUMAN
KIR2DL4
KIR2DL4
273Annotation score:
K7QUT1K7QUT1_HUMAN
KIR2DL4
KIR2DL4
377Annotation score:
A0A0G2JP28A0A0G2JP28_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
273Annotation score:
A0A0C4ZNX8A0A0C4ZNX8_HUMAN
KIR2DL4 Killer-cell Immunoglobulin-...
KIR2DL4
377Annotation score:
A0A0G2JMF5A0A0G2JMF5_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
312Annotation score:
A0A0G2JLM0A0A0G2JLM0_HUMAN
Killer cell immunoglobulin-like rec...
KIR2DL4
312Annotation score:
There are more potential isoformsShow all

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU182349 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000621932; ENSP00000480075; ENSG00000277076

Similar proteinsi

Entry informationi

Entry nameiA0A0G2JMV5_HUMAN
AccessioniPrimary (citable) accession number: A0A0G2JMV5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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