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Protein
Submitted name:

Negative elongation factor E

Gene

NELFE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Negative elongation factor EImported
Gene namesi
Name:NELFEImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:13974 NELFE

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili8 – 35Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR033102 NELFE
PANTHERiPTHR17250 PTHR17250, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A0A0G2JI50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLVIPPGLSE EEEALQKKFN KLKKKKKALL ALKKQSSSST TSQGGVKRSL
60 70 80 90 100
SEQPVMDTAT ATEQAKQLVK SGAISAIKAE TKNSGFKRSR TLEGKLKDPE
110 120 130 140 150
KGPVPTFQPF QRSISADDDL QESSRRPQRK SLYESDRLRE LGPDGEEAEG
160 170 180 190 200
PGAGDGPPRS FDWGYEERSG AHSSASPPRS RSRDRSHERN RDRDRDRERD
210 220 230 240
RDRDRDRDRE RDRDRDRDRD RDRERDRDRE RDRDRDREGP
Length:240
Mass (Da):27,628
Last modified:July 22, 2015 - v1
Checksum:i33E03CD0650469AA
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P18615NELFE_HUMAN
Negative elongation factor E
NELFE RD, RDBP
380Annotation score:
A0A0A0MSN9A0A0A0MSN9_HUMAN
Negative elongation factor E
NELFE
333Annotation score:
A2ABK4A2ABK4_HUMAN
Negative elongation factor E
NELFE
159Annotation score:
E9PD43E9PD43_HUMAN
Negative elongation factor E
NELFE
260Annotation score:
A0A0A0MT02A0A0A0MT02_HUMAN
Negative elongation factor E
NELFE
293Annotation score:
E7EWR7E7EWR7_HUMAN
Negative elongation factor E
NELFE
57Annotation score:
E7ENC7E7ENC7_HUMAN
Negative elongation factor E
NELFE
36Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei240Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662849 Genomic DNA No translation available.
AL844853 Genomic DNA No translation available.
BX005143 Genomic DNA No translation available.
CR388219 Genomic DNA No translation available.
CR753845 Genomic DNA No translation available.
CR759782 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000418423; ENSP00000395175; ENSG00000229363
ENST00000424967; ENSP00000411724; ENSG00000231044
ENST00000435435; ENSP00000396604; ENSG00000233801
ENST00000449057; ENSP00000393793; ENSG00000206357
ENST00000456281; ENSP00000396971; ENSG00000206268

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662849 Genomic DNA No translation available.
AL844853 Genomic DNA No translation available.
BX005143 Genomic DNA No translation available.
CR388219 Genomic DNA No translation available.
CR753845 Genomic DNA No translation available.
CR759782 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000418423; ENSP00000395175; ENSG00000229363
ENST00000424967; ENSP00000411724; ENSG00000231044
ENST00000435435; ENSP00000396604; ENSG00000233801
ENST00000449057; ENSP00000393793; ENSG00000206357
ENST00000456281; ENSP00000396971; ENSG00000206268

Organism-specific databases

HGNCiHGNC:13974 NELFE
GenAtlasiSearch...

Family and domain databases

InterProiView protein in InterPro
IPR033102 NELFE
PANTHERiPTHR17250 PTHR17250, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0G2JI50_HUMAN
AccessioniPrimary (citable) accession number: A0A0G2JI50
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: September 12, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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