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UniProtKB - A0A0G2JGL8 (A0A0G2JGL8_MOUSE)
Protein
RNA helicase
Gene
Dhx30
Organism
Mus musculus (Mouse)
Status
Functioni
Catalytic activityi
- EC:3.6.4.13ARBA annotation
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ATP hydrolysis activity Source: RHEA
- nucleic acid binding Source: InterPro
- RNA helicase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HelicaseARBA annotation, Hydrolase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:Dhx30Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1920081, Dhx30 |
VEuPathDBi | HostDB:ENSMUSG00000032480 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000032480, Expressed in substantia nigra and 319 other tissues |
ExpressionAtlasi | A0A0G2JGL8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 436 – 604 | Helicase ATP-bindingInterPro annotationAdd BLAST | 169 | |
Domaini | 646 – 819 | Helicase C-terminalInterPro annotationAdd BLAST | 174 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 145 – 192 | DisorderedSequence analysisAdd BLAST | 48 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 287 – 307 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000158279 |
Family and domain databases
Gene3Di | 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR011545, DEAD/DEAH_box_helicase_dom IPR002464, DNA/RNA_helicase_DEAH_CS IPR011709, DUF1605 IPR007502, Helicase-assoc_dom IPR014001, Helicase_ATP-bd IPR001650, Helicase_C IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00270, DEAD, 1 hit PF04408, HA2, 1 hit PF00271, Helicase_C, 1 hit PF07717, OB_NTP_bind, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit SM00847, HA2, 1 hit SM00490, HELICc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00690, DEAH_ATP_HELICASE, 1 hit PS51192, HELICASE_ATP_BIND_1, 1 hit PS51194, HELICASE_CTER, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All
A0A0G2JGL8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQASPTPSST HVCQPCPWRD HHSRLNVNIS NMAASRDLLK EFPQPKNLLN
60 70 80 90 100
SVIGRALGIS HAKDKLVYVH TNGPKKKKVT LHIKWPKSVE VEGYGSKKID
110 120 130 140 150
AERQAAAAAC QLFKGWGLLG PRNELFDAAK YRVLADRFGS PADSWWRPEP
160 170 180 190 200
TMPPTSWRQL NPENIRPGGP AGLSRSLGRE EEEDEEEELE EGTIDVTEFL
210 220 230 240 250
SMTQQDSHNP LRDSRGGSFE MTDDDSAIRA LTQFPLPKNL LAKVIQIATS
260 270 280 290 300
SSTAKNLMQF HTVGTKTKLA TLTLLWPCPM TFVAKGRRKA EAENKAAALA
310 320 330 340 350
CKKLKSLGLV DRNNEPLTHA MYNLASLREL GETQRRPCTI QVPEPILRKI
360 370 380 390 400
EAFLSHYPVD SSWISPELRL QSDDILPLGK DSGPLSDPIT GKPYMPLSEA
410 420 430 440 450
EEVRLSQSLL ELWRRRGPIW QEAPQLPVDP HRDTILSAIE QHPVVVISGD
460 470 480 490 500
TGCGKTTRIP QLLLERYVTE GRGARCNVII TQPRRISAVS VAQRVSHELG
510 520 530 540 550
PSLRRNVGFQ VRLESKPPAR GGALLFCTVG ILLRKLQSNP SLEGVSHVIV
560 570 580 590 600
DEVHERDVNT DFLLILLKGL QRLNPALRLV LMSATGDNER FSRYFGGCPV
610 620 630 640 650
IKVPGFMYPV KEHYLEDILA KLGKHQYPHR HRHHESEDEC ALDLDLVTDL
660 670 680 690 700
VLHIDARGEP GGILCFLPGW QEIKGVQQRL QEALGMHESK YLILPVHSNI
710 720 730 740 750
PMMDQKAIFQ QPPLGVRKIV LATNIAETSI TVNDIVHVVD SGLHKEERYD
760 770 780 790 800
LKTKVSCLET VWVSRANVIQ RRGRAGRCQS GFAYHLFPRS RLEKMVPFQV
810 820 830 840 850
PEILRTPLEN LVLQAKIHMP EKTAVEFLSK AVDSPNIKAV DEAVILLQEI
860 870 880 890 900
GVLDQREYLT TLGQRLAHIS TDPRLAKAIV LAAIFRCLHP LLVVVSCLTR
910 920 930 940 950
DPFSSSLQNR AEVDKVKALL SHDSGSDHLA FVRAVAGWEE VLRWQDRTSR
960 970 980 990 1000
ENYLEENLLY APSLRFIHGL IKQFSENIYE AFLVGKPSDC TLPSAQCNEY
1010 1020 1030 1040 1050
SEEEELVKGV LMAGLYPNLI QVRQGKVTRQ GKFKPNSVTY RTKSGNILLH
1060 1070 1080 1090 1100
KSTINREATR LRSRWLTYFM AVKSNGSVFV RDSSQVHPLA VLLLTDGDVH
1110 1120 1130 1140 1150
IRDDGRRATI SLSDSDLLRL EGDSRTVRLL REFRRALGRM VERSLRSELA
1160 1170 1180
ALPLSVQQEH GQLLALLAEL LRGPCGSFDM RKTADD
Computationally mapped potential isoform sequencesi
There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ99PU8 | DHX30_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 Helg | 1,217 | Annotation score: | ||
A0A0G2JEN0 | A0A0G2JEN0_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 73 | Annotation score: | ||
A0A0G2JGU3 | A0A0G2JGU3_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 49 | Annotation score: | ||
A0A0G2JGY7 | A0A0G2JGY7_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 134 | Annotation score: | ||
A0A0G2JE53 | A0A0G2JE53_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 175 | Annotation score: | ||
A0A0G2JEN9 | A0A0G2JEN9_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 12 | Annotation score: | ||
A0A0G2JGD9 | A0A0G2JGD9_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 101 | Annotation score: | ||
A0A0G2JEY7 | A0A0G2JEY7_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 98 | Annotation score: | ||
A0A0G2JFR1 | A0A0G2JFR1_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 72 | Annotation score: | ||
A0A0G2JGL1 | A0A0G2JGL1_MOUSE | ATP-dependent RNA helicase DHX30 | Dhx30 | 239 | Annotation score: |
Sequence databases
RefSeqi | XP_006512373.1, XM_006512310.3 XP_017169104.1, XM_017313615.1 XP_017169105.1, XM_017313616.1 |
Genome annotation databases
Ensembli | ENSMUST00000196171.5; ENSMUSP00000143616.2; ENSMUSG00000032480.18 |
GeneIDi | 72831 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_006512373.1, XM_006512310.3 XP_017169104.1, XM_017313615.1 XP_017169105.1, XM_017313616.1 |
3D structure databases
SMRi | A0A0G2JGL8 |
ModBasei | Search... |
Proteomic databases
ProteomicsDBi | 314507 |
Protocols and materials databases
Antibodypediai | 13009, 163 antibodies from 23 providers |
DNASUi | 72831 |
Genome annotation databases
Ensembli | ENSMUST00000196171.5; ENSMUSP00000143616.2; ENSMUSG00000032480.18 |
GeneIDi | 72831 |
Organism-specific databases
CTDi | 22907 |
MGIi | MGI:1920081, Dhx30 |
VEuPathDBi | HostDB:ENSMUSG00000032480 |
Phylogenomic databases
GeneTreei | ENSGT00940000158279 |
Miscellaneous databases
BioGRID-ORCSi | 72831, 17 hits in 73 CRISPR screens |
ChiTaRSi | Dhx30, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000032480, Expressed in substantia nigra and 319 other tissues |
ExpressionAtlasi | A0A0G2JGL8, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR011545, DEAD/DEAH_box_helicase_dom IPR002464, DNA/RNA_helicase_DEAH_CS IPR011709, DUF1605 IPR007502, Helicase-assoc_dom IPR014001, Helicase_ATP-bd IPR001650, Helicase_C IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00270, DEAD, 1 hit PF04408, HA2, 1 hit PF00271, Helicase_C, 1 hit PF07717, OB_NTP_bind, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit SM00847, HA2, 1 hit SM00490, HELICc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00690, DEAH_ATP_HELICASE, 1 hit PS51192, HELICASE_ATP_BIND_1, 1 hit PS51194, HELICASE_CTER, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0G2JGL8_MOUSE | |
Accessioni | A0A0G2JGL8Primary (citable) accession number: A0A0G2JGL8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 22, 2015 |
Last sequence update: | July 22, 2015 | |
Last modified: | May 25, 2022 | |
This is version 44 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |