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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Candidatus Amesbacteria bacterium GW2011_GWC1_46_24
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi155 – 162ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:UX46_C0001G0108Imported
OrganismiCandidatus Amesbacteria bacterium GW2011_GWC1_46_24Imported
Taxonomic identifieri1618363 [NCBI]
Taxonomic lineageiBacteriaCandidatus Amesbacteria
Proteomesi
  • UP000034853 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini147 – 278AAAInterPro annotationAdd BLAST132
Domaini358 – 427Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0G1PH81-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIDKEKVWKA VLEALRLAVS PGTYGTYLKQ TELADVREKD GRLLCEVGCA
60 70 80 90 100
SSFAKNTLEQ RYWGQITEEL ERVTGNKCEI ILIVKSRKAD EQDSISGPLF
110 120 130 140 150
ESKEVIKGGW KKANLRETFT FDNYAVAGSN QMAFAASQAV ARKPGEAYNP
160 170 180 190 200
LFIYGGVGVG KTHLMQAIGH EVLNNDRGSV LFCSGEEFTN DLVEAIRFKS
210 220 230 240 250
TDKIRLRYRK VKLLMIDDVQ FIAGKPTVQE EFFHTFNAIQ KEGGQIVMTS
260 270 280 290 300
DRPPAEISKL EERLRSRFGA GLIVDIGPAD FELRTAILLI KSRQRKIDLP
310 320 330 340 350
MEAAQVIANK IEGVRELEGF LVRLISEAEM KQQEITKEWV EEVLEIAKPG
360 370 380 390 400
NGRAKIITST EVFSVVGNYY RLGIQQLKGE RRTKMIAWPR QILMYLLRYE
410 420 430 440 450
LKLPLTEVGR MVGDRDHTTV MHGSNKVKLG METDQRIKTE VEDIKKKLFT
Length:450
Mass (Da):50,958
Last modified:July 22, 2015 - v1
Checksum:iF2C0184631B0386A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LCMH01000001 Genomic DNA Translation: KKU32121.1

Genome annotation databases

EnsemblBacteriaiKKU32121; KKU32121; UX46_C0001G0108
PATRICifig|1618363.3.peg.119

Similar proteinsi

Entry informationi

Entry nameiA0A0G1PH81_9BACT
AccessioniPrimary (citable) accession number: A0A0G1PH81
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: July 18, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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