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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Candidatus Nomurabacteria bacterium GW2011_GWF2_40_12
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi154 – 161ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:UT78_C0007G0028Imported
OrganismiCandidatus Nomurabacteria bacterium GW2011_GWF2_40_12Imported
Taxonomic identifieri1618776 [NCBI]
Taxonomic lineageiBacteriaCandidatus Nomurabacteria
Proteomesi
  • UP000034301 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini146 – 278AAAInterPro annotationAdd BLAST133
Domaini356 – 425Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0G0T7Z1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTKELWKNC LMEIETGISK ANFSTWFKNT SIIKEDTGII YIGVPNEFVR
60 70 80 90 100
DWLINKYHKL ITKTIADAYE NMRAVEYTIV KTENSKQEPT VTTEITIEKE
110 120 130 140 150
LPLKDLYINQ EDNLNPRYQF NSFIVGTFNE LAYAASQAII ESPGTKYNPF
160 170 180 190 200
FIYGGTGLGK THLIQAVGNS IKEKYPNKKV HYMTLEKFAT DFVNSLQNNK
210 220 230 240 250
ANSFKEKYRK YDLLIIDDIQ FIGKMEKIQE ELFHTFNTFH ENNKQIIFSS
260 270 280 290 300
DKHPNYIPEL ADRLKSRFAA GMIVDISEPE YESRLAILKV KLRELNVDLA
310 320 330 340 350
EELVEYVAGS VQGNIRELEG SLNLIVCQYR LKNKPLTLME VKNLLKNSMR
360 370 380 390 400
PKKNMAIKDV VKIVSEYYKL EEASVYEKTR KKEIVKARQV VMYLLREDFN
410 420 430 440
VSYPLIGQKL GGKDHTTVIH SCLKIKEDLK NDSQLLQELE QIRIMFK
Length:447
Mass (Da):51,957
Last modified:July 22, 2015 - v1
Checksum:i303D8D573BB863FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LBYC01000007 Genomic DNA Translation: KKR43175.1

Genome annotation databases

EnsemblBacteriaiKKR43175; KKR43175; UT78_C0007G0028
PATRICifig|1618776.3.peg.395

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LBYC01000007 Genomic DNA Translation: KKR43175.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiKKR43175; KKR43175; UT78_C0007G0028
PATRICifig|1618776.3.peg.395

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0G0T7Z1_9BACT
AccessioniPrimary (citable) accession number: A0A0G0T7Z1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: July 18, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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