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Protein

Guanylate kinase

Gene

gmk

Organism
Salmonella enterica I
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotationImported
ORF Names:CVR97_16235Imported, SE14_03963Imported
OrganismiSalmonella enterica IImported
Taxonomic identifieri59201 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000034636 Componenti: Chromosome
  • UP000228538 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

SMRiA0A0F7JD21
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 184Guanylate kinase-likeInterPro annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0F7JD21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQGTLYIVS APSGAGKSSL IQALLKTQPL YDTQVSVSHT TRAPRPGEVH
60 70 80 90 100
GEHYFFVNHD EFKTMIGREA FLEHAEVFGN YYGTSRETIE QVLATGVDVF
110 120 130 140 150
LDIDWQGAQQ IREKMPQARS IFILPPSKIE LDRRLRGRGQ DSEEVIAKRM
160 170 180 190 200
AQAVAEMSHY AEYDYLIVND DFDTALSDLK TIIRAERLRM SRQKQRHNAL

ISKLLAD
Length:207
Mass (Da):23,499
Last modified:July 22, 2015 - v1
Checksum:iA26FF5C1FB40970B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011428 Genomic DNA Translation: AKH09369.1
PHGX01000050 Genomic DNA Translation: PJH60909.1
RefSeqiWP_000046969.1, NZ_PHGX01000050.1

Genome annotation databases

EnsemblBacteriaiAKH09369; AKH09369; SE14_03963
OCS95396; OCS95396; A7B04_00665
OCS97609; OCS97609; A7B05_18845
PATRICifig|59201.158.peg.4042

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011428 Genomic DNA Translation: AKH09369.1
PHGX01000050 Genomic DNA Translation: PJH60909.1
RefSeqiWP_000046969.1, NZ_PHGX01000050.1

3D structure databases

SMRiA0A0F7JD21
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAKH09369; AKH09369; SE14_03963
OCS95396; OCS95396; A7B04_00665
OCS97609; OCS97609; A7B05_18845
PATRICifig|59201.158.peg.4042

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0F7JD21_SALET
AccessioniPrimary (citable) accession number: A0A0F7JD21
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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