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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Thermotoga sp. (strain RQ2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotationSAAS annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei23SubstrateUniRule annotation1
Binding sitei27SubstrateUniRule annotation1
Active sitei75UniRule annotation1
Active sitei75Proton donor/acceptorUniRule annotation1
Binding sitei102SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotationSAAS annotation (EC:4.2.3.3UniRule annotationSAAS annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotation
Ordered Locus Names:TRQ2_1634Imported
OrganismiThermotoga sp. (strain RQ2)Imported
Taxonomic identifieri126740 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000001687 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 122MGSInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni49 – 52Substrate bindingUniRule annotation4
Regioni69 – 70Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01734
OMAiRACDVHN

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0F6AMT9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDRPRRYKI FMDKKKRIAL IAHDRRKRDL LEWVSFNLGT LSKHELYATG
60 70 80 90 100
TTGALLQEKL GLKVHRLKSG PLGGDQQIGA MIAEGKIDVL IFFWDPLEPQ
110 120 130 140 150
AHDVDVKALI RIATVYNIPV AITRSTADFL ISSPLMNDVY EKIQIDYEEE
160
LERRIRKVVE GEEEET
Length:166
Mass (Da):19,092
Last modified:June 24, 2015 - v1
Checksum:i838975E7566BBE85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000969 Genomic DNA Translation: ACB09969.1
RefSeqiWP_004080162.1, NC_010483.1

Genome annotation databases

EnsemblBacteriaiACB09969; ACB09969; TRQ2_1634
GeneIDi29652779
KEGGitrq:TRQ2_1634

Similar proteinsi

Entry informationi

Entry nameiA0A0F6AMT9_THESQ
AccessioniPrimary (citable) accession number: A0A0F6AMT9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: April 25, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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