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Protein
Submitted name:

Copper-exporting P-type ATPase CopA

Gene

copA

Organism
Escherichia coli
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi14PROSITE-ProRule annotation1
Metal bindingi17PROSITE-ProRule annotation1
Metal bindingi110PROSITE-ProRule annotation1
Metal bindingi113PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Copper-exporting P-type ATPase CopAImported
Submitted name:
Copper-transporting ATPaseImported
Submitted name:
Cu+ exporting ATPaseImported
Submitted name:
Lead, cadmium, zinc and mercury transporting ATPaseImported
Gene namesi
Name:copAImported
ORF Names:AML07_05835Imported, APZ14_17180Imported, AW106_21375Imported, COD30_24815Imported, FORC28_4597Imported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000054864 Componenti: Unassembled WGS sequence
  • UP000218167 Componenti: Unassembled WGS sequence
  • UP000094451 Componenti: Chromosome
  • UP000194319 Componenti: Unassembled WGS sequence
  • UP000076262 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei185 – 205HelicalUniRule annotationAdd BLAST21
Transmembranei217 – 238HelicalUniRule annotationAdd BLAST22
Transmembranei245 – 264HelicalUniRule annotationAdd BLAST20
Transmembranei284 – 302HelicalUniRule annotationAdd BLAST19
Transmembranei436 – 458HelicalUniRule annotationAdd BLAST23
Transmembranei464 – 487HelicalUniRule annotationAdd BLAST24
Transmembranei778 – 797HelicalUniRule annotationAdd BLAST20
Transmembranei803 – 824HelicalUniRule annotationAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 65HMAInterPro annotationAdd BLAST62
Domaini100 – 163HMAInterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd00371 HMA, 2 hits
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 2 hits
PRINTSiPR00120 HATPASE
SUPFAMiSSF55008 SSF55008, 2 hits
SSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A0F3US90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQIIDLTLD GLSCGHCVKR VKESLEQRPD VEQADVSITE AHVTGTASAE
60 70 80 90 100
QLIETIKQAG YDASVSHPKA KPLAESSIPS EALTAVSEAL PAATADDDDS
110 120 130 140 150
QQLLLSGMSC ASCVTRVQNA LQSVPGVTQA RVNLAERTAL VMGSASPQDL
160 170 180 190 200
VQAVEKAGYG AEAIEDDAKR RERQQETAVA TMKRFRWQAI VALAVGIPVM
210 220 230 240 250
VWGMIGDNMM VTADNRSLWL VIGLITLAVM VFAGGHFYRS AWKSLLNGAA
260 270 280 290 300
TMDTLVALGT GVAWLYSMSV NLWPQWFPME ARHLYYEASA MIIGLINLGH
310 320 330 340 350
MLEARARQRS SKALEKLLDL TPPTARLVTD EGEKSVPLAE VQPGMLLRLT
360 370 380 390 400
TGDRVPVDGE ITQGEAWLDE AMLTGEPIPQ QKGEGESVHA GTVVQDGSVL
410 420 430 440 450
FRASAVGSHT TLSRIIRMVR QAQSSKPEIG QLADKISAVF VPVVVVIALV
460 470 480 490 500
SAAIWYFFGP APQIVYTLVI ATTVLIIACP CALGLATPMS IISGVGRAAE
510 520 530 540 550
FGVLVRDADA LQRASTLDTV VFDKTGTLTE GKPQVVAVKT FADVDEAQAL
560 570 580 590 600
RLAAALEQGS SHPLARAILD KAGDMQLPQV NGFRTLRGLG VSGEAEGHAL
610 620 630 640 650
LLGNQALLNE QQVGTKAIEA EITAQASQGA TPVLLAVDGK AVALLAVRDP
660 670 680 690 700
LRSDSVAALQ RLHKAGYRLV MLTGDNPTTA NAIAKEAGID EVIAGVLPDG
710 720 730 740 750
KAEAIKRLQS EGRQVAMVGD GINDAPALAQ ADVGIAMGGG SDVAIETAAI
760 770 780 790 800
TLMRHSLMGV ADALAISRAT LRNMKQNLLG AFIYNSIGIP VAAGILWPFT
810 820 830
GTLLNPVVAG AAMALSSITV VSNANRLLRF KPKE
Length:834
Mass (Da):87,937
Last modified:June 24, 2015 - v1
Checksum:i1FDAE23F11466931
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP012693 Genomic DNA Translation: AOM47577.1
LMBK01000547 Genomic DNA Translation: KST27767.1
LOFS01000057 Genomic DNA Translation: KYR57217.1
NENZ01000051 Genomic DNA Translation: OTD97317.1
NWBE01000047 Genomic DNA Translation: PBR07202.1
RefSeqiWP_000078269.1, NZ_PVMH01000004.1

Genome annotation databases

EnsemblBacteriaiAOM47577; AOM47577; FORC28_4597
KST27767; KST27767; APZ14_17180
KYR57217; KYR57217; AML07_05835
PATRICifig|562.11480.peg.1311

Similar proteinsi

Entry informationi

Entry nameiA0A0F3US90_ECOLX
AccessioniPrimary (citable) accession number: A0A0F3US90
Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: July 18, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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