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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Orientia tsutsugamushi str. UT76
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi174 – 181ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:OTSUT76_0454Imported
OrganismiOrientia tsutsugamushi str. UT76Imported
Taxonomic identifieri682184 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
Proteomesi
  • UP000033364 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini166 – 294AAAInterPro annotationAdd BLAST129
Domaini377 – 446Bac_DnaA_CInterPro annotationAdd BLAST70

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili446 – 466Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0F3QZI9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTLLQQPNT TKDELYFHEL WSSVKRDLRH HYGEAVFKSW FSKMNMVDFT
60 70 80 90 100
DSYIKLSAPT NFTRDWIKAN YFDSIRQLLA YYDSSITRVD IVTSAIDHQN
110 120 130 140 150
SDLAFSTQQN TDNNNQQYST KSSNNVIFSS TLDPRFTFDN FVVGRPNELA
160 170 180 190 200
YAAATTVAES PTAVAKSNPL FLYGGVGLGK THLMHAIAWH IQNSSSKRKV
210 220 230 240 250
IYMSAEKFMY QFVQSLRNKD VMSFKEQFRS VDVLMIDDIQ FICGKDSTQE
260 270 280 290 300
EFFHTFNALI DNKRQMVISC DRSPSDLDNI EERIKSRLGW GLVADVHSTT
310 320 330 340 350
YELRLGILQS KVEQLATAVP LKVLEFLAAK ITSNVRELEG ALNKVIAHST
360 370 380 390 400
LVGYEITIEN TQEILRDLLR SNQKTITIDS IQKKVAERYN IKISDMSSSR
410 420 430 440 450
RSRSVTKPRQ LAMYLAKRLT SKSLVDIGKA FGKKDHTTVM HAIKTVEDLS
460
KQEQEFEDEV RLLMRILQN
Length:469
Mass (Da):53,762
Last modified:June 24, 2015 - v1
Checksum:i517520A136E953B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LANZ01000008 Genomic DNA Translation: KJV96864.1

Genome annotation databases

EnsemblBacteriaiKJV96864; KJV96864; OTSUT76_0454
PATRICifig|682184.3.peg.4458

Similar proteinsi

Entry informationi

Entry nameiA0A0F3QZI9_ORITS
AccessioniPrimary (citable) accession number: A0A0F3QZI9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: July 18, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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