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Entry version 61 (29 Sep 2021)
Sequence version 1 (24 Jun 2015)
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Protein
Submitted name:

Lytic transglycosylase SceD

Gene

sceD

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseImported, Hydrolase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Lytic transglycosylase SceDImported
Submitted name:
Putative transglycosylaseImported
Submitted name:
Putative transglycosylase SceDImported
Submitted name:
SceD-like transglycosylase, biomarker for vancomycin-intermediate strainsImported (EC:3.2.-.-Imported)
Submitted name:
TransglycosylaseImported
Submitted name:
Transglycosylase SceDImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sceDImported
ORF Names:BTN44_12825Imported, DD547_02131Imported, DQU54_11985Imported, ELP52_11890Imported, EP54_10955Imported, EQ90_06850Imported, FA040_09445Imported, GO814_01165Imported, GO942_06395Imported, GQX37_08480Imported, GZ128_04935Imported, GZ145_03455Imported, HMPREF3211_02564Imported, NCTC10654_02259Imported, NCTC10702_03324Imported, RK64_11130Imported, SA0759_01759Imported, SA950122_01702Imported, SAGV51_02438Imported, SAGV69_02535Imported, SAHC1335_00037Imported, SAMEA1029536_01612Imported, SAMEA103891420_02708Imported, SAMEA2076468_01896Imported, SAMEA2076503_02240Imported, SAMEA2077334_02003Imported, SAMEA2078260_01890Imported, SAMEA2078588_01861Imported, SAMEA2079501_02053Imported, SAMEA2080344_01825Imported, SAMEA2081063_01840Imported, SAMEA4008569_02091Imported, SAMEA70146418_02240Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStaphylococcus aureusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1280 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501503716328 – 231Sequence analysisAdd BLAST204

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini154 – 231TransglycosylasInterPro annotationAdd BLAST78

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni106 – 153DisorderedSequence analysisAdd BLAST48

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13925, RPF, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023346, Lysozyme-like_dom_sf
IPR010618, RPF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06737, Transglycosylas, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53955, SSF53955, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0E8J2S9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKTLLASSL AVGLGIVAGN AGHEAHASEA DLNKASLAQM AQSNDQTLNQ
60 70 80 90 100
KPIEAGAYNY TFDYEGFTYH FESDGTHFAW NYHATGTNGA DMSAQAPATN
110 120 130 140 150
NVAPSAVQAN QVQSQEVEAP QNAQTQQPQA STSNNSQVTA TPTESKSSEG
160 170 180 190 200
SSVNVNAHLK QIAQRESGGN IHAVNPTSGA AGKYQFLQST WDSVAPAKYK
210 220 230
GVSPANAPES VQDAAAVKLY NTGGAGHWVT A
Length:231
Mass (Da):24,066
Last modified:June 24, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i389994BBC436C11E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP009681 Genomic DNA Translation: AIU86033.1
CP012012 Genomic DNA Translation: ALY19032.1
CP012015 Genomic DNA Translation: ALY26411.1
CP018629 Genomic DNA Translation: AUS76054.1
CP026962 Genomic DNA Translation: AVG64685.1
CP031670 Genomic DNA Translation: AXP71950.1
CACTPG010000010 Genomic DNA Translation: CAA4149749.1
CACTQT010000010 Genomic DNA Translation: CAA4383614.1
CACTWD010000010 Genomic DNA Translation: CAA4690909.1
CACTVV010000012 Genomic DNA Translation: CAA4716241.1
CACUBY010000011 Genomic DNA Translation: CAA5155199.1
CACUNS010000010 Genomic DNA Translation: CAA6098367.1
CACUPZ010000011 Genomic DNA Translation: CAA6259356.1
CACURZ010000009 Genomic DNA Translation: CAA6364907.1
CACUTQ010000010 Genomic DNA Translation: CAA6533576.1
CAIGWX010000009 Genomic DNA Translation: CAC5796580.1
CAIHEN010000005 Genomic DNA Translation: CAC6333729.1
CAIIGD010000008 Genomic DNA Translation: CAC8227970.1
LALJ01000010 Genomic DNA Translation: KMR36810.1
LALQ01000048 Genomic DNA Translation: KMR56459.1
LRQH01000192 Genomic DNA Translation: KXA32704.1
WPTS01000011 Genomic DNA Translation: MVK33755.1
WPXC01000012 Genomic DNA Translation: MVM10318.1
JAAFLQ010000008 Genomic DNA Translation: NDP79192.1
JAAFNF010000009 Genomic DNA Translation: NDR37138.1
JAANEC010000084 Genomic DNA Translation: NUY12553.1
CP030384 Genomic DNA Translation: QFJ00462.1
CP045439 Genomic DNA Translation: QLH98812.1
CP045441 Genomic DNA Translation: QLI01335.1
RZHI01000012 Genomic DNA Translation: RUQ53209.1
UHBX01000004 Genomic DNA Translation: SUL30362.1
UHBY01000003 Genomic DNA Translation: SUL37324.1
SWED01000011 Genomic DNA Translation: TKC11115.1

NCBI Reference Sequences

More...
RefSeqi
WP_000752008.1, NZ_WOFG01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AUS76054; AUS76054; BTN44_12825
AVG64685; AVG64685; RK64_11130
KXA32704; KXA32704; HMPREF3211_02564
SQA08403; SQA08403; NCTC13131_01431
SUL30362; SUL30362; NCTC10654_02259
SUL37324; SUL37324; NCTC10702_03324

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
saur:SABB_02421

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1280.10758.peg.1877

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009681 Genomic DNA Translation: AIU86033.1
CP012012 Genomic DNA Translation: ALY19032.1
CP012015 Genomic DNA Translation: ALY26411.1
CP018629 Genomic DNA Translation: AUS76054.1
CP026962 Genomic DNA Translation: AVG64685.1
CP031670 Genomic DNA Translation: AXP71950.1
CACTPG010000010 Genomic DNA Translation: CAA4149749.1
CACTQT010000010 Genomic DNA Translation: CAA4383614.1
CACTWD010000010 Genomic DNA Translation: CAA4690909.1
CACTVV010000012 Genomic DNA Translation: CAA4716241.1
CACUBY010000011 Genomic DNA Translation: CAA5155199.1
CACUNS010000010 Genomic DNA Translation: CAA6098367.1
CACUPZ010000011 Genomic DNA Translation: CAA6259356.1
CACURZ010000009 Genomic DNA Translation: CAA6364907.1
CACUTQ010000010 Genomic DNA Translation: CAA6533576.1
CAIGWX010000009 Genomic DNA Translation: CAC5796580.1
CAIHEN010000005 Genomic DNA Translation: CAC6333729.1
CAIIGD010000008 Genomic DNA Translation: CAC8227970.1
LALJ01000010 Genomic DNA Translation: KMR36810.1
LALQ01000048 Genomic DNA Translation: KMR56459.1
LRQH01000192 Genomic DNA Translation: KXA32704.1
WPTS01000011 Genomic DNA Translation: MVK33755.1
WPXC01000012 Genomic DNA Translation: MVM10318.1
JAAFLQ010000008 Genomic DNA Translation: NDP79192.1
JAAFNF010000009 Genomic DNA Translation: NDR37138.1
JAANEC010000084 Genomic DNA Translation: NUY12553.1
CP030384 Genomic DNA Translation: QFJ00462.1
CP045439 Genomic DNA Translation: QLH98812.1
CP045441 Genomic DNA Translation: QLI01335.1
RZHI01000012 Genomic DNA Translation: RUQ53209.1
UHBX01000004 Genomic DNA Translation: SUL30362.1
UHBY01000003 Genomic DNA Translation: SUL37324.1
SWED01000011 Genomic DNA Translation: TKC11115.1
RefSeqiWP_000752008.1, NZ_WOFG01000001.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAUS76054; AUS76054; BTN44_12825
AVG64685; AVG64685; RK64_11130
KXA32704; KXA32704; HMPREF3211_02564
SQA08403; SQA08403; NCTC13131_01431
SUL30362; SUL30362; NCTC10654_02259
SUL37324; SUL37324; NCTC10702_03324
KEGGisaur:SABB_02421
PATRICifig|1280.10758.peg.1877

Family and domain databases

CDDicd13925, RPF, 1 hit
InterProiView protein in InterPro
IPR023346, Lysozyme-like_dom_sf
IPR010618, RPF
PfamiView protein in Pfam
PF06737, Transglycosylas, 1 hit
SUPFAMiSSF53955, SSF53955, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0E8J2S9_STAAU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0E8J2S9
Secondary accession number(s): A0A1E8WWM0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: September 29, 2021
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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