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Entry version 32 (11 Dec 2019)
Sequence version 1 (24 Jun 2015)
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Protein
Submitted name:

Nucleoside triphosphate pyrophosphohydrolase

Gene

mazG

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nucleoside triphosphate pyrophosphohydrolaseImported (EC:3.6.1.19Imported, EC:3.6.1.8Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mazGImported
ORF Names:ERS007703_03635Imported, ERS023446_01718Imported, ERS027651_02220Imported, SAMEA2682864_03464Imported, SAMEA2683035_03104Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000183655 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000038802 Componenti: Unassembled WGS sequence
  • UP000049058 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini108 – 182MazGInterPro annotationAdd BLAST75

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004518 MazG_cat
IPR011551 NTP_PyrPHydrolase_MazG

The PANTHER Classification System

More...
PANTHERi
PTHR30522 PTHR30522, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03819 MazG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0E7YXB3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMIVVLVDPR RPTLVPVEAI EFLRGEVQYT EEMPVAVPWS LPAARSAHAG
60 70 80 90 100
NDAPVLLSSD PNHPAVITRL AAGARLISAP DSQRGERLVD AVAMMDKLRT
110 120 130 140 150
AGPWESEQTH DSLRRYLLEE TYELLDAVRS GSVDQLREEL GDLLLQVLFH
160 170 180 190 200
ARIAEDASQS PFTIDDVADT LMRKLGNRAP GVLAGESISL EDQLAQWEAA
210 220 230 240 250
KASEKARKSV ADDVHTGQPA LALAQKVIQR AQKAGLPAHL IPDEITSVSV
260 270 280 290 300
SADVDAENTL RTAVLDFIDR LRCAERAIAV ARRGSNVAEQ LDVTPLGVIT
310 320
EQEWLAHWPT AVNDSRGGSK KRKGMR
Length:326
Mass (Da):35,544
Last modified:June 24, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i648EEE5E67ACF448
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CIEA01000021 Genomic DNA Translation: CKS14036.1
CQGE01000030 Genomic DNA Translation: CNM96111.1
CSAE01000517 Genomic DNA Translation: COW42885.1
FPTZ01000025 Genomic DNA Translation: SGI21972.1
FPXX01000026 Genomic DNA Translation: SGM94123.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CFE42032; CFE42032; ERS007681_03091
CFE56129; CFE56129; ERS007688_02508
CKQ22771; CKQ22771; ERS024213_03416
CKR20077; CKR20077; ERS027661_00777
CKR50975; CKR50975; ERS027652_01599
CKS00542; CKS00542; ERS027653_02435
CKS16385; CKS16385; ERS027656_02645
CKS81814; CKS81814; ERS027654_03755
CKT26988; CKT26988; ERS027646_03259
CKU14378; CKU14378; ERS027666_03848
CNG90830; CNG90830; ERS124361_02270
CNM96111; CNM96111; ERS023446_01718
CNV53474; CNV53474; ERS007670_03517
CNV62330; CNV62330; ERS007663_03776
CNV68065; CNV68065; ERS007665_03532
CNY38576; CNY38576; ERS013471_01430
COV61848; COV61848; ERS007679_02173
COV67697; COV67697; ERS007672_02224
COW26883; COW26883; ERS007741_02018
COW42885; COW42885; ERS007703_03635
COW95332; COW95332; ERS007722_03806
COX33216; COX33216; ERS007720_04313
CRH13654; CRH13654; BN1303_02221

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.211.peg.3323

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CIEA01000021 Genomic DNA Translation: CKS14036.1
CQGE01000030 Genomic DNA Translation: CNM96111.1
CSAE01000517 Genomic DNA Translation: COW42885.1
FPTZ01000025 Genomic DNA Translation: SGI21972.1
FPXX01000026 Genomic DNA Translation: SGM94123.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCFE42032; CFE42032; ERS007681_03091
CFE56129; CFE56129; ERS007688_02508
CKQ22771; CKQ22771; ERS024213_03416
CKR20077; CKR20077; ERS027661_00777
CKR50975; CKR50975; ERS027652_01599
CKS00542; CKS00542; ERS027653_02435
CKS16385; CKS16385; ERS027656_02645
CKS81814; CKS81814; ERS027654_03755
CKT26988; CKT26988; ERS027646_03259
CKU14378; CKU14378; ERS027666_03848
CNG90830; CNG90830; ERS124361_02270
CNM96111; CNM96111; ERS023446_01718
CNV53474; CNV53474; ERS007670_03517
CNV62330; CNV62330; ERS007663_03776
CNV68065; CNV68065; ERS007665_03532
CNY38576; CNY38576; ERS013471_01430
COV61848; COV61848; ERS007679_02173
COV67697; COV67697; ERS007672_02224
COW26883; COW26883; ERS007741_02018
COW42885; COW42885; ERS007703_03635
COW95332; COW95332; ERS007722_03806
COX33216; COX33216; ERS007720_04313
CRH13654; CRH13654; BN1303_02221
PATRICifig|1773.211.peg.3323

Family and domain databases

InterProiView protein in InterPro
IPR004518 MazG_cat
IPR011551 NTP_PyrPHydrolase_MazG
PANTHERiPTHR30522 PTHR30522, 2 hits
PfamiView protein in Pfam
PF03819 MazG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0E7YXB3_MYCTX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0E7YXB3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: December 11, 2019
This is version 32 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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