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Entry version 46 (12 Aug 2020)
Sequence version 1 (24 Jun 2015)
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Protein
Submitted name:

Acetyl-/propionyl-CoA carboxylase subunit beta

Gene

accD6

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigaseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Acetyl-/propionyl-CoA carboxylase subunit betaImported
Submitted name:
Acyl-CoA carboxylase subunit betaImported
Submitted name:
Propionyl-CoA carboxylase subunit betaImported (EC:6.4.1.3Imported)
Submitted name:
Propionyl-CoA carboxylase subunit beta 6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:accD6Imported
ORF Names:DSI38_20410Imported, ERS013471_01685Imported, ERS023446_01401Imported, ERS027646_00895Imported, ERS075361_02919Imported, ERS094182_00869Imported, F6W99_00848Imported, F9908_00515Imported, SAMEA2683035_01247Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000048948 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000047893 Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000042440 Componenti: Unassembled WGS sequence
  • UP000326088 Componenti: Chromosome
  • UP000431688 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 224CoA carboxyltransferase N-terminalInterPro annotationAdd BLAST224
Domaini225 – 473CoA carboxyltransferase C-terminalInterPro annotationAdd BLAST249

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AccD/PCCB family.ARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034733, AcCoA_carboxyl
IPR029045, ClpP/crotonase-like_dom_sf
IPR011763, COA_CT_C
IPR011762, COA_CT_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01039, Carboxyl_trans, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52096, SSF52096, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50989, COA_CT_CTER, 1 hit
PS50980, COA_CT_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0E7XNZ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIMAPEAVG ESLDPRDPLL RLSNFFDDGS VELLHERDRS GVLAAAGTVN
60 70 80 90 100
GVRTIAFCTD GTVMGGAMGV EGCTHIVNAY DTAIEDQSPI VGIWHSGGAR
110 120 130 140 150
LAEGVRALHA VGQVFEAMIR ASGYIPQISV VVGFAAGGAA YGPALTDVVV
160 170 180 190 200
MAPESRVFVT GPDVVRSVTG EDVDMASLGG PETHHKKSGV CHIVADDELD
210 220 230 240 250
AYDRGRRLVG LFCQQGHFDR SKAEAGDTDI HALLPESSRR AYDVRPIVTA
260 270 280 290 300
ILDADTPFDE FQANWAPSMV VGLGRLSGRT VGVLANNPLR LGGCLNSESA
310 320 330 340 350
EKAARFVRLC DAFGIPLVVV VDVPGYLPGV DQEWGGVVRR GAKLLHAFGE
360 370 380 390 400
CTVPRVTLVT RKTYGGAYIA MNSRSLNATK VFAWPDAEVA VMGAKAAVGI
410 420 430 440 450
LHKKKLAAAP EHEREALHDQ LAAEHERIAG GVDSALDIGV VDEKIDPAHT
460 470
RSKLTEALAQ APARRGRHKN IPL
Length:473
Mass (Da):50,136
Last modified:June 24, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i94AD7EBD88F233C3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CNGE01000108 Genomic DNA Translation: CKR89557.1
CQAC01000024 Genomic DNA Translation: CNG99145.1
CQGE01000022 Genomic DNA Translation: CNM83958.1
CQTT01000036 Genomic DNA Translation: CNY46833.1
CVKR01000005 Genomic DNA Translation: CRF25448.1
WFKV01000001 Genomic DNA Translation: KAB7807544.1
CP044345 Genomic DNA Translation: QEX90072.1
QSXJ01001062 Genomic DNA Translation: REM62048.1
FPTZ01000006 Genomic DNA Translation: SGH48356.1

NCBI Reference Sequences

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RefSeqi
WP_003900487.1, NZ_WUJD01000033.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC46676; AMC46676; RN05_2400
CKO21598; CKO21598; ERS024213_00063
CKQ91127; CKQ91127; ERS027656_00219
CKR21019; CKR21019; ERS027644_00734
CKR89557; CKR89557; ERS027646_00895
CKS13138; CKS13138; ERS027653_02606
CKT13961; CKT13961; ERS027666_02199
CKU47594; CKU47594; ERS031537_00601
CNH21949; CNH21949; ERS124361_03148
CNM83958; CNM83958; ERS023446_01401
CNY46833; CNY46833; ERS013471_01685
CRH09761; CRH09761; BN1303_00324
CRH11037; CRH11037; BN1213_01074

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23491552

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.206.peg.1648

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CNGE01000108 Genomic DNA Translation: CKR89557.1
CQAC01000024 Genomic DNA Translation: CNG99145.1
CQGE01000022 Genomic DNA Translation: CNM83958.1
CQTT01000036 Genomic DNA Translation: CNY46833.1
CVKR01000005 Genomic DNA Translation: CRF25448.1
WFKV01000001 Genomic DNA Translation: KAB7807544.1
CP044345 Genomic DNA Translation: QEX90072.1
QSXJ01001062 Genomic DNA Translation: REM62048.1
FPTZ01000006 Genomic DNA Translation: SGH48356.1
RefSeqiWP_003900487.1, NZ_WUJD01000033.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC46676; AMC46676; RN05_2400
CKO21598; CKO21598; ERS024213_00063
CKQ91127; CKQ91127; ERS027656_00219
CKR21019; CKR21019; ERS027644_00734
CKR89557; CKR89557; ERS027646_00895
CKS13138; CKS13138; ERS027653_02606
CKT13961; CKT13961; ERS027666_02199
CKU47594; CKU47594; ERS031537_00601
CNH21949; CNH21949; ERS124361_03148
CNM83958; CNM83958; ERS023446_01401
CNY46833; CNY46833; ERS013471_01685
CRH09761; CRH09761; BN1303_00324
CRH11037; CRH11037; BN1213_01074
GeneIDi23491552
PATRICifig|1773.206.peg.1648

Family and domain databases

InterProiView protein in InterPro
IPR034733, AcCoA_carboxyl
IPR029045, ClpP/crotonase-like_dom_sf
IPR011763, COA_CT_C
IPR011762, COA_CT_N
PfamiView protein in Pfam
PF01039, Carboxyl_trans, 1 hit
SUPFAMiSSF52096, SSF52096, 2 hits
PROSITEiView protein in PROSITE
PS50989, COA_CT_CTER, 1 hit
PS50980, COA_CT_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0E7XNZ4_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0E7XNZ4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: August 12, 2020
This is version 46 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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