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Entry version 38 (02 Dec 2020)
Sequence version 1 (24 Jun 2015)
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Protein

ORC1-type DNA replication protein

Gene

SSOP1_0240

Organism
Saccharolobus solfataricus (Sulfolobus solfataricus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in regulation of DNA replication.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei208ATPUniRule annotation1
Binding sitei220ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi67 – 71ATPUniRule annotation5

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell divisionImported, DNA replicationUniRule annotationARBA annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ORC1-type DNA replication proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SSOP1_0240Imported, SULA_1273Imported, SULB_1274Imported, SULC_1272Imported, SULG_06300Imported, SULH_06300Imported, SULI_06300Imported, SULM_06300Imported, SULN_06300Imported, SULO_06310Imported, SULZ_06545Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharolobus solfataricus (Sulfolobus solfataricus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri2287 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSaccharolobus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000278715 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000273194 Componenti: Chromosome
  • UP000033057 Componenti: Chromosome
  • UP000282269 Componenti: Chromosome
  • UP000076770 Componenti: Chromosome i
  • UP000275843 Componenti: Chromosome
  • UP000033085 Componenti: Chromosome
  • UP000267993 Componenti: Chromosome
  • UP000033106 Componenti: Chromosome
  • UP000269431 Componenti: Chromosome
  • UP000273443 Componenti: Chromosome

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0E3KC68

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini55 – 209AAAInterPro annotationAdd BLAST155
Domaini303 – 385Cdc6_CInterPro annotationAdd BLAST83

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CDC6/cdc18 family.UniRule annotationARBA annotation

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
58376at2157

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08768, Cdc6_C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01407, ORC1_type_DNA_replic_protein, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR015163, Cdc6_C
IPR014277, Orc1/Cdc6_arc
IPR027417, P-loop_NTPase
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13401, AAA_22, 1 hit
PF09079, Cdc6_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 1 hit
SM01074, Cdc6_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02928, TIGR02928, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0E3KC68-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDIIDEVIS SFKTSSIFIN REYLLPDYIP DELPHREDQI RKIASILAPL
60 70 80 90 100
YREEKPNNIF IYGLTGTGKT AVVKFVLSKL HKKFLGKFKH VYINTRQIDT
110 120 130 140 150
PYRVLADLLE SLDVKVPFTG LSIAELYRRL VKAVRDYGSQ VVIVLDEIDA
160 170 180 190 200
FVKKYNDDIL YKLSRINSEV NKSKISFIGI TNDVKFVDLL DPRVKSSLSE
210 220 230 240 250
EEIIFPPYNA EELEDILTKR AQMAFKPGVL PDNVIKLCAA LAAREHGDAR
260 270 280 290 300
RALDLLRVSG EIAERMKDTK VKEEYVYMAK EEIERDRVRD IILTLPFHSK
310 320 330 340 350
LVLMAVVSIS SEENVVSTTG AVYETYLNIC KKLGVEAVTQ RRVSDIINEL
360 370 380 390
DMVGILTAKV VNRGRYGKTK EIGLAVDKNI IVRSLIESDS RFADLWS
Length:397
Mass (Da):45,167
Last modified:June 24, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA2A32A355A3ADD74
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP011055 Genomic DNA Translation: AKA73574.1
CP011056 Genomic DNA Translation: AKA76272.1
CP011057 Genomic DNA Translation: AKA78964.1
CP033235 Genomic DNA Translation: AZF68042.1
CP033236 Genomic DNA Translation: AZF70662.1
CP033237 Genomic DNA Translation: AZF73282.1
CP033238 Genomic DNA Translation: AZF75907.1
CP033239 Genomic DNA Translation: AZF78516.1
CP033240 Genomic DNA Translation: AZF81120.1
CP033241 Genomic DNA Translation: AZF83759.1
LT549890 Genomic DNA Translation: SAI83794.1

NCBI Reference Sequences

More...
RefSeqi
WP_009990521.1, NZ_LT549890.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AKA73574; AKA73574; SULB_1274
AKA76272; AKA76272; SULC_1272
AKA78964; AKA78964; SULA_1273

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
44129226

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssoa:SULA_1273
ssof:SULC_1272
ssol:SULB_1274

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|2287.6.peg.1327

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011055 Genomic DNA Translation: AKA73574.1
CP011056 Genomic DNA Translation: AKA76272.1
CP011057 Genomic DNA Translation: AKA78964.1
CP033235 Genomic DNA Translation: AZF68042.1
CP033236 Genomic DNA Translation: AZF70662.1
CP033237 Genomic DNA Translation: AZF73282.1
CP033238 Genomic DNA Translation: AZF75907.1
CP033239 Genomic DNA Translation: AZF78516.1
CP033240 Genomic DNA Translation: AZF81120.1
CP033241 Genomic DNA Translation: AZF83759.1
LT549890 Genomic DNA Translation: SAI83794.1
RefSeqiWP_009990521.1, NZ_LT549890.1

3D structure databases

SMRiA0A0E3KC68
ModBaseiSearch...

Genome annotation databases

EnsemblBacteriaiAKA73574; AKA73574; SULB_1274
AKA76272; AKA76272; SULC_1272
AKA78964; AKA78964; SULA_1273
GeneIDi44129226
KEGGissoa:SULA_1273
ssof:SULC_1272
ssol:SULB_1274
PATRICifig|2287.6.peg.1327

Phylogenomic databases

OrthoDBi58376at2157

Family and domain databases

CDDicd08768, Cdc6_C, 1 hit
Gene3Di1.10.10.10, 1 hit
HAMAPiMF_01407, ORC1_type_DNA_replic_protein, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR015163, Cdc6_C
IPR014277, Orc1/Cdc6_arc
IPR027417, P-loop_NTPase
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF13401, AAA_22, 1 hit
PF09079, Cdc6_C, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 1 hit
SM01074, Cdc6_C, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
SSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR02928, TIGR02928, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0E3KC68_SACSO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0E3KC68
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: December 2, 2020
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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