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Protein
Submitted name:

Secretin receptor

Gene

SCTR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Secretin receptorImported
Gene namesi
Name:SCTRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000080293.9
HGNCiHGNC:10608 SCTR

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei76 – 96HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080293

Expressioni

Gene expression databases

BgeeiENSG00000080293 Expressed in 93 organ(s), highest expression level in body of pancreas
ExpressionAtlasiA0A0D9SFV7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0D9SFV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 59G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST59
Domaini74 – 150G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118800

Family and domain databases

Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR002144 GPCR_2_secretin_rcpt
PANTHERiPTHR12011:SF29 PTHR12011:SF29, 1 hit
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF02793 HRM, 1 hit
PRINTSiPR00249 GPCRSECRETIN
PR00490 SECRETINR
SMARTiView protein in SMART
SM00008 HormR, 1 hit
SUPFAMiSSF111418 SSF111418, 1 hit
PROSITEiView protein in PROSITE
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A0D9SFV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWDNISCWPS SVPGRMVEVE CPRFLRMLTS RNGSLFRNCT QDGWSETFPR
60 70 80 90 100
PNLACGVNVN DSSNEKRHSY LLKLKVMYTV GYSSSLVMLL VALGILCAFR
110 120 130 140 150
RLHCTRNYIH MHLFVSFILR ALSNFIKDAV LFSSDDVTYC DAHRAGCKLV
Length:150
Mass (Da):17,134
Last modified:May 27, 2015 - v1
Checksum:i4D102C71D7AC3247
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P47872SCTR_HUMAN
Secretin receptor
SCTR
440Annotation score:
A0A0D9SFY2A0A0D9SFY2_HUMAN
Secretin receptor
SCTR
243Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei150Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013275 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000630739; ENSP00000486930; ENSG00000080293

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013275 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A0D9SFV7
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000630739; ENSP00000486930; ENSG00000080293

Organism-specific databases

EuPathDBiHostDB:ENSG00000080293.9
HGNCiHGNC:10608 SCTR
OpenTargetsiENSG00000080293
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118800

Gene expression databases

BgeeiENSG00000080293 Expressed in 93 organ(s), highest expression level in body of pancreas
ExpressionAtlasiA0A0D9SFV7 baseline and differential

Family and domain databases

Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR002144 GPCR_2_secretin_rcpt
PANTHERiPTHR12011:SF29 PTHR12011:SF29, 1 hit
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF02793 HRM, 1 hit
PRINTSiPR00249 GPCRSECRETIN
PR00490 SECRETINR
SMARTiView protein in SMART
SM00008 HormR, 1 hit
SUPFAMiSSF111418 SSF111418, 1 hit
PROSITEiView protein in PROSITE
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0D9SFV7_HUMAN
AccessioniPrimary (citable) accession number: A0A0D9SFV7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 7, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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