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Protein
Submitted name:

Histone-lysine N-methyltransferase EHMT1

Gene

EHMT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Histone-lysine N-methyltransferase EHMT1Imported
Gene namesi
Name:EHMT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000181090.17
HGNCiHGNC:24650 EHMT1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000181090

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0D9SEY2

Expressioni

Gene expression databases

BgeeiENSG00000181090 Expressed in 199 organ(s), highest expression level in testis
ExpressionAtlasiA0A0D9SEY2 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A0D9SEY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 97ANK_REP_REGIONInterPro annotationAdd BLAST97
Repeati1 – 30ANKPROSITE-ProRule annotationAdd BLAST30
Repeati31 – 55ANKPROSITE-ProRule annotationAdd BLAST25
Repeati65 – 97ANKPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00780000121845

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR038035 EHMT1
PANTHERiPTHR22884:SF364 PTHR22884:SF364, 1 hit
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 22 potential isoforms that are computationally mapped.Show allAlign All

A0A0D9SEY2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XPLMEAAENN HLEAVKYLIK AGALVDPKDA EGSTCLHLAA KKGHYEVVQY
60 70 80 90 100
LLSNGQMDVN CQDDGGWTPM IWATEYKHVD LVKLLLSKGS DINIRDNVGC

IYSKYTLG
Length:108
Mass (Da):11,921
Last modified:May 27, 2015 - v1
Checksum:iD7FB10679474ACE5
GO

Computationally mapped potential isoform sequencesi

There are 22 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9H9B1EHMT1_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1 EUHMTASE1, GLP, KIAA1876, KMT1D
1,298Annotation score:
A0A1B0GV09A0A1B0GV09_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
1,267Annotation score:
A0A1B0GU48A0A1B0GU48_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
981Annotation score:
A0A0D9SFS4A0A0D9SFS4_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
134Annotation score:
A0A0D9SFX4A0A0D9SFX4_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
268Annotation score:
A0A0D9SER3A0A0D9SER3_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
137Annotation score:
A0A0D9SFG7A0A0D9SFG7_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
139Annotation score:
A0A0D9SEQ1A0A0D9SEQ1_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
432Annotation score:
A0A1B0GVZ8A0A1B0GVZ8_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
543Annotation score:
A0A1B0GUD1A0A1B0GUD1_HUMAN
Histone-lysine N-methyltransferase ...
EHMT1
556Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365502 Genomic DNA No translation available.
AL590627 Genomic DNA No translation available.
AL611925 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000486164; ENSP00000486127; ENSG00000181090

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365502 Genomic DNA No translation available.
AL590627 Genomic DNA No translation available.
AL611925 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A0D9SEY2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A0D9SEY2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000486164; ENSP00000486127; ENSG00000181090

Organism-specific databases

EuPathDBiHostDB:ENSG00000181090.17
HGNCiHGNC:24650 EHMT1
OpenTargetsiENSG00000181090
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00780000121845

Miscellaneous databases

ChiTaRSiEHMT1 human

Gene expression databases

BgeeiENSG00000181090 Expressed in 199 organ(s), highest expression level in testis
ExpressionAtlasiA0A0D9SEY2 baseline and differential

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR038035 EHMT1
PANTHERiPTHR22884:SF364 PTHR22884:SF364, 1 hit
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0D9SEY2_HUMAN
AccessioniPrimary (citable) accession number: A0A0D9SEY2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: September 12, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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