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Protein

Homeobox protein cut-like

Gene

CUX1

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1255 – 1314HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein cut-likeUniRule annotation
Gene namesi
Name:CUX1Imported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini553 – 640CUTInterPro annotationAdd BLAST88
Domaini945 – 1032CUTInterPro annotationAdd BLAST88
Domaini1128 – 1215CUTInterPro annotationAdd BLAST88
Domaini1253 – 1313HomeoboxInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili17 – 37Sequence analysisAdd BLAST21
Coiled coili68 – 88Sequence analysisAdd BLAST21
Coiled coili112 – 196Sequence analysisAdd BLAST85
Coiled coili201 – 228Sequence analysisAdd BLAST28
Coiled coili237 – 274Sequence analysisAdd BLAST38
Coiled coili296 – 330Sequence analysisAdd BLAST35
Coiled coili335 – 355Sequence analysisAdd BLAST21
Coiled coili721 – 741Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000063019
OMAiVANWRRT

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 3 hits
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 3 hits
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042 CUT, 3 hits
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D9RZP2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR
60 70 80 90 100
EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL NVYKRLIDVP
110 120 130 140 150
DPVPALDLGQ QLQLKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI
160 170 180 190 200
KALKEKIREY EQTLKNQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK
210 220 230 240 250
LEEAEHKVQS LQTALEKTRT ELFDLKTKYD EETTAKADEI EMIMTDLERA
260 270 280 290 300
NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE
310 320 330 340 350
VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLSAKNSTLK
360 370 380 390 400
QLEEKLKGQA DYEEVKKELN ILKSMEFAPS EGAGTQDAAK PLEVLLMEKN
410 420 430 440 450
RSLQSENAAL RISNSDLSGS ARRKGKDQPE SRRPGSLPAP PPSQLPRNPG
460 470 480 490 500
EQASNTNGTH QFSPAGLSQD FFSSSLASPS LPLASTGKFA LNSLLQRQLM
510 520 530 540 550
QSFYSKAMQE AGSTSMIFST GPYSTNSISS QSPLQQSPDV NGMAPSPSQS
560 570 580 590 600
ESAGSVSEGE EMDTAEIARQ VKEQLIKHNI GQRIFGHYVL GLSQGSVSEI
610 620 630 640 650
LARPKPWNKL TVRGKEPFHK MKQFLSDEQN ILALRSIQGR QRENPGQSLN
660 670 680 690 700
RLFQEVPKRR NGSEGNITTR IRASETGSDE AIKSILEQAK RELQVQKTAE
710 720 730 740 750
PAQPSSASGS GNSDDAIRSI LQQARREMEA QQAALDPALK QAPLSQSDIT
760 770 780 790 800
ILTPKLLSTS PMPTVSSYPP LAISLKKPSA APEAGASALP NPPALKKEAQ
810 820 830 840 850
DAPGLDPQGA ADCAQGVLRQ VKNEVGRSGA WKDHWWSAVQ PERRNAASSE
860 870 880 890 900
EAKAEETGAG KEKGSGGSGG GSQPRAERSQ LQGPSSSEYW KEWPSAESPY
910 920 930 940 950
SQSSELSLTG ASRSETPQNS PLPSSPIVPM SKPTKPSVPP LTPEQYEVYM
960 970 980 990 1000
YQEVDTIELT RQVKEKLAKN GICQRIFGEK VLGLSQGSVS DMLSRPKPWS
1010 1020 1030 1040 1050
KLTQKGREPF IRMQLWLNGE LGQGVLPVQG QQQGPVLHSV TSLQDPLQQG
1060 1070 1080 1090 1100
CVSSESTPKT SASCSPAPES PMSSSESVKS LTELVQQPCP PIEASKDGKP
1110 1120 1130 1140 1150
PEPSDPPASD SQPATPLPLS GHSALSIQEL VAMSPELDTY GITKRVKEVL
1160 1170 1180 1190 1200
TDNNLGQRLF GETILGLTQG SVSDLLARPK PWHKLSLKGR EPFVRMQLWL
1210 1220 1230 1240 1250
NDPNNVEKLM DMKRMEKKAY MKRRHSSVSD SQPCEPPSVG TEYSQGASPQ
1260 1270 1280 1290 1300
PQHQLKKPRV VLAPEEKEAL KRAYQQKPYP SPKTIEDLAT QLNLKTSTVI
1310 1320 1330 1340 1350
NWFHNYRSRI RRELFIEEIQ AGSQGQAGAS DSPSARSGRA APSSEGDSCD
1360 1370 1380 1390 1400
GVEATEGPGS ADTEEPKSQG EAEREEAPRP AEQTEPPPSG TPGPDDARDD
1410 1420 1430 1440 1450
DHEGGPAEGP GPLSSPATAT ATATATAAPA APEDAATSAA AAPGEGPAAR
1460 1470 1480 1490 1500
SSAPPPSSSS SSSSSSAPRR PSSLQSLFGL PEAAGARDSR DNPLRKKKAA
1510 1520
NLNSIIHRLE KAASREEPIE WEF
Length:1,523
Mass (Da):166,246
Last modified:May 27, 2015 - v1
Checksum:i44F9E47E86440884
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01139528 Genomic DNA No translation available.
AQIB01139529 Genomic DNA No translation available.
AQIB01139530 Genomic DNA No translation available.
AQIB01139531 Genomic DNA No translation available.
AQIB01139532 Genomic DNA No translation available.
AQIB01139533 Genomic DNA No translation available.
AQIB01139534 Genomic DNA No translation available.
AQIB01139535 Genomic DNA No translation available.
RefSeqiXP_008016633.1, XM_008018442.1

Genome annotation databases

EnsembliENSCSAT00000016160; ENSCSAP00000014081; ENSCSAG00000018062
GeneIDi103246681

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01139528 Genomic DNA No translation available.
AQIB01139529 Genomic DNA No translation available.
AQIB01139530 Genomic DNA No translation available.
AQIB01139531 Genomic DNA No translation available.
AQIB01139532 Genomic DNA No translation available.
AQIB01139533 Genomic DNA No translation available.
AQIB01139534 Genomic DNA No translation available.
AQIB01139535 Genomic DNA No translation available.
RefSeqiXP_008016633.1, XM_008018442.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCSAT00000016160; ENSCSAP00000014081; ENSCSAG00000018062
GeneIDi103246681

Organism-specific databases

CTDi1523

Phylogenomic databases

GeneTreeiENSGT00530000063019
OMAiVANWRRT

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 3 hits
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 3 hits
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042 CUT, 3 hits
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0D9RZP2_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9RZP2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: April 25, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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