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Protein

Alpha-1,4 glucan phosphorylase

Gene

PYGL

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation

Catalytic activityi

((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
Biological processCarbohydrate metabolismUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,4 glucan phosphorylaseUniRule annotation (EC:2.4.1.1UniRule annotation)
Gene namesi
Name:PYGLImported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 24

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei681N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

SMRiA0A0D9RRG2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycogen phosphorylase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000016886
KOiK00688
OMAiARDIWNM

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 1 hit
PfamiView protein in Pfam
PF00343 Phosphorylase, 1 hit
PIRSFiPIRSF000460 Pprylas_GlgP, 1 hit
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D9RRG2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKPLTDQEK RRQISIRGIV GVENVAELKK GFNRHLHFTL VKDRNVATPR
60 70 80 90 100
DYYFALAHTV RDHLVGRWIR TQQHYYDKCP KRVYYLSLEF YMGRTLQNTM
110 120 130 140 150
INLGLQNACD EAIYQLGLDI EELEEIEEDA GLGNGGLGRL AACFLDSMAT
160 170 180 190 200
LGLAAYGYGI RYEYGIFNQK IRDGWQVEEA DDWLRYGNPW EKSRPEFMLP
210 220 230 240 250
VHFYGKVEHT NTGTKWIDTQ VVLALPYDTP VPGYMNNTVN TMRLWSARAP
260 270 280 290 300
NDFNLRDFNV GDYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV
310 320 330 340 350
VAATLQDIIR RFKASKFGST RGAGTVFDAF PDQVAIQLND THPALAIPEL
360 370 380 390 400
MRIFVDIEKL PWSKAWELTQ KTFAYTNHTV LPEALERWPV DLVEKLLPRH
410 420 430 440 450
LEIIYEINQK HLDKIVALFP KDVDRLRRMS LIEEEGSKRI NMAHLCIVGS
460 470 480 490 500
HTVNGVAKIH SDIVKTKVFK DFSELEPDKF QNKTNGITPR RWLLLCNPGL
510 520 530 540 550
AELIAEKIGE DYVKDLSQLT KLHSFLGDDI FLRELAKVKQ ENKLKFSQFL
560 570 580 590 600
EKEYKVKINP SSMFDVQVKR IHEYKRQLLN CLHVITMYNR IKKDPKKLFV
610 620 630 640 650
PRTVIIGGKA APGYHMAKMI IKLITSVADV VNNDPMVGSK LKVIFLENYR
660 670 680 690 700
VSLAEKVIPA TDLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM
710 720 730 740 750
AEEAGEENLF IFGMRVDDVA ALDKKGYEAK EYYEALPELK LVIDQIDNGF
760 770 780 790 800
FSPKQPDLFK DIINMLFYHD RFKVFADYEA YVKCQDKVSQ LYMNPKAWNT
810 820 830 840
MVLKNIAASG KFSSDRTIKE YAQNIWNVEP SDLKISLSNE SNKVNGN
Length:847
Mass (Da):97,144
Last modified:May 27, 2015 - v1
Checksum:iE85613B375AA7E02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01058443 Genomic DNA No translation available.
AQIB01058444 Genomic DNA No translation available.
AQIB01058445 Genomic DNA No translation available.
AQIB01058446 Genomic DNA No translation available.
AQIB01058447 Genomic DNA No translation available.
AQIB01058448 Genomic DNA No translation available.
AQIB01058449 Genomic DNA No translation available.
AQIB01058450 Genomic DNA No translation available.
AQIB01058451 Genomic DNA No translation available.
AQIB01058452 Genomic DNA No translation available.
RefSeqiXP_007984859.1, XM_007986668.1

Genome annotation databases

EnsembliENSCSAT00000013194; ENSCSAP00000011201; ENSCSAG00000015103
GeneIDi103228970
KEGGicsab:103228970

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01058443 Genomic DNA No translation available.
AQIB01058444 Genomic DNA No translation available.
AQIB01058445 Genomic DNA No translation available.
AQIB01058446 Genomic DNA No translation available.
AQIB01058447 Genomic DNA No translation available.
AQIB01058448 Genomic DNA No translation available.
AQIB01058449 Genomic DNA No translation available.
AQIB01058450 Genomic DNA No translation available.
AQIB01058451 Genomic DNA No translation available.
AQIB01058452 Genomic DNA No translation available.
RefSeqiXP_007984859.1, XM_007986668.1

3D structure databases

SMRiA0A0D9RRG2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCSAT00000013194; ENSCSAP00000011201; ENSCSAG00000015103
GeneIDi103228970
KEGGicsab:103228970

Organism-specific databases

CTDi5836

Phylogenomic databases

GeneTreeiENSGT00390000016886
KOiK00688
OMAiARDIWNM

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 1 hit
PfamiView protein in Pfam
PF00343 Phosphorylase, 1 hit
PIRSFiPIRSF000460 Pprylas_GlgP, 1 hit
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0D9RRG2_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9RRG2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: October 10, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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