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Protein
Submitted name:

Epithelial cell adhesion molecule

Gene

EPCAM

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Epithelial cell adhesion moleculeImported
Gene namesi
Name:EPCAMImported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei266 – 289HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500234562924 – 314Sequence analysisAdd BLAST291

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 135Thyroglobulin type-1InterPro annotationAdd BLAST73

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000018245
KOiK06737
OMAiREKPYDV

Family and domain databases

CDDicd00191 TY, 1 hit
Gene3Di4.10.800.10, 1 hit
InterProiView protein in InterPro
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf
PfamiView protein in Pfam
PF00086 Thyroglobulin_1, 1 hit
SMARTiView protein in SMART
SM00211 TY, 1 hit
SUPFAMiSSF57610 SSF57610, 1 hit
PROSITEiView protein in PROSITE
PS00484 THYROGLOBULIN_1_1, 1 hit
PS51162 THYROGLOBULIN_1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D9RM83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPPQVLAFG LLLAAATASF AAAQKECICE NYKLAVNCFL NDNGQCQCTS
60 70 80 90 100
IGAQNTVLCS KLAAKCLVMK AEMNGSKLGR RAKPEGAIQN NDGLYDPDCD
110 120 130 140 150
ESGLFKAKQC NGTSTCWCVN TAGVRRTDKD TEITCSERVR TYWIIIELKH
160 170 180 190 200
KAREKPYDVQ SLRTALEEAI KTRYQLDPKF ITNILYEDNV ITIDLVQNSS
210 220 230 240 250
QKTQNDVDIA DVAYYFEKDV KGESLFHSKK MDLRVNGEQL DLDPGQTLIY
260 270 280 290 300
YVDEKAPEFS MQGLKAGVIA VIVVVVIAVV AGIVVLVISR KKRMAKYEKA
310
EIKEMGEIHR ELNA
Length:314
Mass (Da):34,879
Last modified:May 27, 2015 - v1
Checksum:i151244C0BD2674CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01038543 Genomic DNA No translation available.
RefSeqiXP_007968904.1, XM_007970713.1

Genome annotation databases

EnsembliENSCSAT00000011655; ENSCSAP00000009722; ENSCSAG00000013561
GeneIDi103220323
KEGGicsab:103220323

Similar proteinsi

Entry informationi

Entry nameiA0A0D9RM83_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9RM83
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: April 25, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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