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Protein
Submitted name:

Glucagon like peptide 1 receptor

Gene

GLP1R

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Glucagon like peptide 1 receptorImported
Gene namesi
Name:GLP1RImported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei145 – 167HelicalSequence analysisAdd BLAST23
Transmembranei179 – 196HelicalSequence analysisAdd BLAST18
Transmembranei241 – 261HelicalSequence analysisAdd BLAST21
Transmembranei268 – 287HelicalSequence analysisAdd BLAST20
Transmembranei307 – 332HelicalSequence analysisAdd BLAST26
Transmembranei353 – 370HelicalSequence analysisAdd BLAST18
Transmembranei382 – 405HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500234494024 – 464Sequence analysisAdd BLAST441

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 130G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST86
Domaini144 – 406G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST263

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118800
OMAiRNSNMNY

Family and domain databases

CDDicd15268 7tmB1_GLP1R, 1 hit
Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR003290 GPCR_2_GLP1/glucagon_rcpt
IPR003292 GPCR_2_GLP1_rcpt
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
PANTHERiPTHR12011:SF245 PTHR12011:SF245, 1 hit
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF02793 HRM, 1 hit
PRINTSiPR01353 GLUCAGNFAMLY
PR01355 GLUCAGNLIKER
PR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00008 HormR, 1 hit
SUPFAMiSSF111418 SSF111418, 1 hit
PROSITEiView protein in PROSITE
PS00649 G_PROTEIN_RECEP_F2_1, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D9REZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGTPGPLRL ALLLLGVVGR AGPRPQGATV SLWETVQKWR EYRRQCQRSL
60 70 80 90 100
TEDPPPTTDL FCNRTFDEYA CWPDGEPGSF VNVSCPWYLP WASSVPQGHV
110 120 130 140 150
YRFCTAEGLW LQKDNSSLPW RDLSECEESK RGERSSPEEQ LLSLYIIYTV
160 170 180 190 200
GYALSFSALV IASAILLGFR HLHCTRNYIH LNLFASFILR ALSVFIKDAA
210 220 230 240 250
LKWMYSTAAQ QHQWDGLLSY QDSLGCRVVF LLMQYCVAAN YYWLLVEGVY
260 270 280 290 300
LYTLLAFSVF SEQRIFRLYV SVGWGVPLLF VVPWGIVKYL YEDEGCWTRN
310 320 330 340 350
SNMNYWLIIR LPILFAIGVN FLIFVRVICI VVSKLKANLM CKTDIKCRLA
360 370 380 390 400
KSTLTLIPLL GTHEVIFAFV MDEHARGTLR FIKLFTELSF TSFQGLMVAI
410 420 430 440 450
LYCFVNNEKV QLEFRKSWER WRLEHLHIQR DSSMKPLKCP TSSLSSGATA
460
GSSMYTATCQ ASCS
Length:464
Mass (Da):53,068
Last modified:May 27, 2015 - v1
Checksum:i503939E2394F59AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01159879 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCSAT00000009051; ENSCSAP00000007183; ENSCSAG00000010991

Similar proteinsi

Entry informationi

Entry nameiA0A0D9REZ4_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9REZ4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: March 28, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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