Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

CHRNG

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CHRNGImported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei242 – 264HelicalSequence analysisAdd BLAST23
Transmembranei276 – 296HelicalSequence analysisAdd BLAST21
Transmembranei308 – 331HelicalSequence analysisAdd BLAST24
Transmembranei474 – 496HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500234466523 – 516Sequence analysisAdd BLAST494

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 241Neur_chan_LBDInterPro annotationAdd BLAST216
Domaini248 – 491Neur_chan_membInterPro annotationAdd BLAST244

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000144023
KOiK04818
OMAiCNLIARA

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D9R2C7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHGGQGLLLL LPLLAVCLGV QGRNQEDRLL ADLMQNYDPN LRPAERDSDV
60 70 80 90 100
VNVSLKLTLT NLISLNEREE ALTTNVWIEM QWCDYRLRWD PRDYEGLWVL
110 120 130 140 150
RVPSTMVWRP DIVLENNVDG VFEVALYCNV LVSPDGCIYW LPPAIFRSAC
160 170 180 190 200
SISVTYFPFD WQNCSLIFQS QTYSTNEIDL QLSQEDGQTI EWIFIDPEAF
210 220 230 240 250
TENGEWAIQH RPAKMLLDPA APAQEAGHQK VVFYLLIQRK PLFYVINIIA
260 270 280 290 300
PCVLISSVAI LIYFLPAKAG GQKCTVAINV LLAQTVFLFL VAKKVPETSQ
310 320 330 340 350
AVPLISKYLT FLLVVTILIV VNAVVVLNVS LRSPHTHSMA RGVRKVFLRL
360 370 380 390 400
LPQLLRMHVR PLAPAAVQDT QPRLQNGSSG WSITTGEVAL CLPRSELLFQ
410 420 430 440 450
QWQQQGLVAA ALEKLEKGPE LEPSQFCGSL KQAAPAIQAC VEACNLIARA
460 470 480 490 500
RHQQSHFDNG NEEWFLVGRV LDRVCFLAML SLFVCGTAGI FLMAHYNRVP
510
ALPFPGDPRP YLPSPD
Length:516
Mass (Da):57,871
Last modified:May 27, 2015 - v1
Checksum:i9192BED0C162DFB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01001222 Genomic DNA No translation available.
AQIB01001223 Genomic DNA No translation available.
AQIB01001224 Genomic DNA No translation available.
AQIB01001225 Genomic DNA No translation available.
RefSeqiXP_007964850.1, XM_007966659.1

Genome annotation databases

EnsembliENSCSAT00000004516; ENSCSAP00000002766; ENSCSAG00000006488
GeneIDi103218086
KEGGicsab:103218086

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01001222 Genomic DNA No translation available.
AQIB01001223 Genomic DNA No translation available.
AQIB01001224 Genomic DNA No translation available.
AQIB01001225 Genomic DNA No translation available.
RefSeqiXP_007964850.1, XM_007966659.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCSAT00000004516; ENSCSAP00000002766; ENSCSAG00000006488
GeneIDi103218086
KEGGicsab:103218086

Organism-specific databases

CTDi1146

Phylogenomic databases

GeneTreeiENSGT00910000144023
KOiK04818
OMAiCNLIARA

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0D9R2C7_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9R2C7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 7, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again