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Protein

Dephospho-CoA kinase

Gene

coaE

Organism
Tanticharoenia sakaeratensis NBRC 103193
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + 3'-dephospho-CoA = ADP + CoA.UniRule annotation

Pathwayi: coenzyme A biosynthesis

This protein is involved in step 5 of the subpathway that synthesizes CoA from (R)-pantothenate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Type III pantothenate kinase (coaX)
  2. Coenzyme A biosynthesis bifunctional protein CoaBC (Tasa_009_243)
  3. Coenzyme A biosynthesis bifunctional protein CoaBC (Tasa_009_243)
  4. Phosphopantetheine adenylyltransferase (coaD)
  5. Dephospho-CoA kinase (coaE)
This subpathway is part of the pathway coenzyme A biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CoA from (R)-pantothenate, the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 15ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processCoenzyme A biosynthesisUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayi
UPA00241;UER00356

Names & Taxonomyi

Protein namesi
Recommended name:
Dephospho-CoA kinaseUniRule annotation (EC:2.7.1.24UniRule annotation)
Alternative name(s):
Dephosphocoenzyme A kinaseUniRule annotation
Gene namesi
Name:coaEUniRule annotation
ORF Names:Tasa_009_018Imported
OrganismiTanticharoenia sakaeratensis NBRC 103193Imported
Taxonomic identifieri1231623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeTanticharoenia
Proteomesi
  • UP000032679 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the CoaE family.UniRule annotation

Family and domain databases

CDDicd02022 DPCK, 1 hit
HAMAPiMF_00376 Dephospho_CoA_kinase, 1 hit
InterProiView protein in InterPro
IPR001977 Depp_CoAkinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01121 CoaE, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00152 TIGR00152, 1 hit
PROSITEiView protein in PROSITE
PS51219 DPCK, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D6MIW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLVLGLTGGM GAGKSTIARL FRLRHIPVFD ADATVHRLQG RHGAAVAPIA
60 70 80 90 100
TLCPQAVADG RIRRDVLRTF ATRSPDAMRA LEAIMHPLVA QARAQFLRTA
110 120 130 140 150
RGRGAWLCVL DIPLLFEVGA DRDCDLVVVA HAPLATRRRR IAVRRGVSME
160 170 180 190
AADALIARQM SDRARLARAD IVIPTGLSRH VAAVQVARLL DRLYKLRP
Length:198
Mass (Da):21,627
Last modified:May 27, 2015 - v1
Checksum:i971058C4DB0B35E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BALE01000009 Genomic DNA Translation: GAN53223.1
RefSeqiWP_048846999.1, NZ_BALE01000009.1

Genome annotation databases

EnsemblBacteriaiGAN53223; GAN53223; Tasa_009_018

Similar proteinsi

Entry informationi

Entry nameiA0A0D6MIW6_9PROT
AccessioniPrimary (citable) accession number: A0A0D6MIW6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: September 27, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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