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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Muricauda lutaonensis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi180 – 187ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:VC82_2Imported
OrganismiMuricauda lutaonensisImported
Taxonomic identifieri516051 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeMuricauda
Proteomesi
  • UP000032726 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini172 – 302AAAInterPro annotationAdd BLAST131
Domaini383 – 452Bac_DnaA_CInterPro annotationAdd BLAST70

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili334 – 354Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK02313

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D5YPD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVTADSVWN NCLVFIKDNI QPQAFKTWFE PIKPVRLTDN ALSIQVPSKF
60 70 80 90 100
FYEWLEEHYV KLLKVALTKE LGQNAKLVYV IKMENKYGNS EPFTEKIPSS
110 120 130 140 150
NRSSMDPQEL NVPITSKNPQ LKNPFVIPGI RNIKIESQLN PNYNFENFLE
160 170 180 190 200
GDSNRLARSA GLAVANKPGG TSFNPLLIFG GVGLGKTHLA HAIGVEIKDK
210 220 230 240 250
YPEKTVLYIS AEKFTQQYIE SVKKNTRNDF IHFYQLIDTL IIDDVQFLSG
260 270 280 290 300
KSGTQDVFFH IFNHLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA
310 320 330 340 350
ELQSPDYETR VSILKNKLYR DGVEMPEEII DHVAKNIKTN IRELEGAIIS
360 370 380 390 400
LIAQSSFNKK EVTLELAQQV VEKFVKNTKR EVSIDYIQKV VSDYFEMDVA
410 420 430 440 450
TLQSKTRKRH IVQARQLAMF FAKKYTKASL ASIGSQIGKR DHATVLHACK
460 470
TVDNLAETDK QFRKYLEDLN KKFT
Length:474
Mass (Da):54,215
Last modified:May 27, 2015 - v1
Checksum:iFF53AF61F8D30DCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011071 Genomic DNA Translation: AKA33696.1
RefSeqiWP_045800571.1, NZ_CP011071.1

Genome annotation databases

EnsemblBacteriaiAKA33696; AKA33696; VC82_2
KEGGimlt:VC82_2
PATRICifig|516051.4.peg.2

Similar proteinsi

Entry informationi

Entry nameiA0A0D5YPD6_9FLAO
AccessioniPrimary (citable) accession number: A0A0D5YPD6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: July 18, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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