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UniProtKB - A0A0D4CLZ8 (A0A0D4CLZ8_LACMC)

Entry version 28 (02 Dec 2020)
Sequence version 1 (27 May 2015)
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Protein

Aldehyde-alcohol dehydrogenase

Gene

LBLM1_09530

Organism
Lactobacillus mucosae LM1
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductaseUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Aldehyde-alcohol dehydrogenaseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LBLM1_09530Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLactobacillus mucosae LM1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1130798 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000003645 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 416AldedhInterPro annotationAdd BLAST396
Domaini473 – 859Fe-ADHInterPro annotationAdd BLAST387

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.UniRule annotation
In the N-terminal section; belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_007207_1_0_9

Database of Orthologous Groups

More...OrthoDBi		1456634at2

Family and domain databases

Conserved Domains Database

More...CDDi		cd08178, AAD_C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.309.10, 1 hit
3.40.605.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR034789, AAD_C
IPR001670, ADH_Fe/GldA
IPR018211, ADH_Fe_CS
IPR039697, Alcohol_dehydrogenase_Fe
IPR016161, Ald_DH/histidinol_DH
IPR016163, Ald_DH_C
IPR016162, Ald_DH_N
IPR015590, Aldehyde_DH_dom
IPR012079, Bifunc_Ald-ADH

The PANTHER Classification System

More...PANTHERi		PTHR11496, PTHR11496, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00171, Aldedh, 1 hit
PF00465, Fe-ADH, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF000111, ALDH_ADH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53720, SSF53720, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00913, ADH_IRON_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0D4CLZ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVKAKATVK ATEKPKDKEQ TAEELINGLI DKSEKALDQL RTFSQEQVDK 
        60         70         80         90        100
ICQNLALAAE EHHMDLAISA AEETGRGVAE DKAIKNIYAS EYIWNNIRND 
       110        120        130        140        150
KTVGIIDEDD ENQMITIADP LGVIAGVVPV TNPTSTVIFK SIIALKTRNT 
       160        170        180        190        200
IIFSFHPQAF KSCLKTGQIL EAAAEAAGAP KDVIQWIPQC SRENTTALLQ 
       210        220        230        240        250
NPRIATILAT GGPGLVKAAY SSGNPALGVG PGNGPAYIEK SANIDRSIYD 
       260        270        280        290        300
IVLSKTFDNG MICATENSVV IDDEIYDQVK EAFKKWNCYF LKPSEIPTFT 
       310        320        330        340        350
NGFIDPDRHQ VRGPIAGRSA NDIAEMCGLK NVPANTKVLI AELDGVGPKY 
       360        370        380        390        400
PLSAEKLSPV LTMYRAKSRE DAFRICSELL AYGGEGHTAA IHTNDDELIK 
       410        420        430        440        450
EYSLKMKASR IIVNSPSGLG GIGNVYNNMT PSFTLGTGSY GSNSISHNVS 
       460        470        480        490        500
DWDLLNIKKV AMRRDNPQWV QIPPKVYFQR NSLKYLKEIP NINKAFIVTG 
       510        520        530        540        550
PGMVKRGYIQ RVIDQLRLRN NRVQYEIFSD IEPDPSTDTV DKGVAWMNDF 
       560        570        580        590        600
QPDTIIALGG GSPMDAAKAM WMFYEHPDTT WNGVRQKYLD IRKRAYKIGR 
       610        620        630        640        650
PKKAQFIGIP TTSGTGSEVT PFAVITNSKT HVKYPLADYA LTPDIAIVDS 
       660        670        680        690        700
QFVESVPANT TAWTGLDVLT HATESYVSVM ATDYTRGWSL EAIKGVMENL 
       710        720        730        740        750
EASVKGDKLA RKKMHDSSTI AGLAFANAFL GITHSLAHKM GGAFDLPHGL 
       760        770        780        790        800
VIAIALPQVI RFNAKRPTKL AMWPHYEDYR ADKDYAAIAR FLGLKGDTTE 
       810        820        830        840        850
ELVEAYVQKI IELAHKCGVT LSLKANGVKR EDFDKVVDQL AVLAYEDQCT 
       860        870 
TANPVEPLVS QLKELLERCY EGTGVETEE
Length:879
Mass (Da):96,656
Last modified:May 27, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2F94752314F2A56C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP011013 Genomic DNA Translation: AJT51177.1

NCBI Reference Sequences

More...RefSeqi		WP_006500481.1, NZ_CP011013.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AJT51177; AJT51177; LBLM1_09530

Database of genes from NCBI RefSeq genomes

More...GeneIDi		41532307

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		lmu:LBLM1_09530

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011013 Genomic DNA Translation: AJT51177.1
RefSeqiWP_006500481.1, NZ_CP011013.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAJT51177; AJT51177; LBLM1_09530
GeneIDi41532307
KEGGilmu:LBLM1_09530

Phylogenomic databases

HOGENOMiCLU_007207_1_0_9
OrthoDBi1456634at2

Family and domain databases

CDDicd08178, AAD_C, 1 hit
Gene3Di3.40.309.10, 1 hit
3.40.605.10, 1 hit
InterProiView protein in InterPro
IPR034789, AAD_C
IPR001670, ADH_Fe/GldA
IPR018211, ADH_Fe_CS
IPR039697, Alcohol_dehydrogenase_Fe
IPR016161, Ald_DH/histidinol_DH
IPR016163, Ald_DH_C
IPR016162, Ald_DH_N
IPR015590, Aldehyde_DH_dom
IPR012079, Bifunc_Ald-ADH
PANTHERiPTHR11496, PTHR11496, 1 hit
PfamiView protein in Pfam
PF00171, Aldedh, 1 hit
PF00465, Fe-ADH, 1 hit
PIRSFiPIRSF000111, ALDH_ADH, 1 hit
SUPFAMiSSF53720, SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00913, ADH_IRON_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0D4CLZ8_LACMC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0D4CLZ8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: December 2, 2020
This is version 28 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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