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Protein

Probable malate:quinone oxidoreductase

Gene

mqo1

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotationSAAS annotation

Cofactori

FADUniRule annotationSAAS annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo2), Probable malate:quinone oxidoreductase (mqo1_2), Malate dehydrogenase (quinone) (mqo1_1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo), Malate dehydrogenase (quinone) (mqo2_1), Probable malate:quinone oxidoreductase (mqo1), Probable malate:quinone oxidoreductase (mqo1), Malate dehydrogenase (quinone) (CV021_16750), Malate dehydrogenase (quinone) (mqo2_3)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
Biological processTricarboxylic acid cycleUniRule annotationSAAS annotation
LigandFADUniRule annotationSAAS annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqo1Imported
Synonyms:mqoUniRule annotationImported
ORF Names:BTN44_14305Imported, EP54_04345Imported, EQ90_00040Imported, HMPREF3211_00545Imported, NCTC10654_02537Imported, NCTC13131_01710Imported, NCTC13196_01591Imported, NCTC13812_02505Imported, NCTC9944_02524Imported, RK64_12615Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000250033 Componenti: Unassembled WGS sequence
  • UP000070177 Componenti: Unassembled WGS sequence
  • UP000248832 Componenti: Chromosome 1
  • UP000255075 Componenti: Unassembled WGS sequence
  • UP000251686 Componenti: Unassembled WGS sequence
  • UP000035281 Componenti: Chromosome
  • UP000254674 Componenti: Unassembled WGS sequence
  • UP000236484 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00116

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0D3QAJ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTQHSKTDV ILIGGGIMSA TLGTLLKELS PEKNIKVFEK LAQPGEESSN
60 70 80 90 100
VWNNAGTGHS ALCELNYTKE GKDGTVDCSK AIKINEQYQI SKQFWAYLVK
110 120 130 140 150
TGQLDNPDRF IQAVPHMSFV IGEDNVAFIK SRVATLKKSI LFEKMKLSQD
160 170 180 190 200
EEEMKSWVPL MIEGRKSDEP IALTYDETGT DVNFGALTAK LFDNLEQRGV
210 220 230 240 250
GIQYKQNVLD IKKQKSGVWL VKVKDLETNE TTTYESDFVF IGAGGASLPL
260 270 280 290 300
LQKTGIKQSK HIGGFPVSGL FLRCTNQEVI DRHHAKVYGK AAVGAPPMSV
310 320 330 340 350
PHLDTRFVDG KRSLLFGPFA GFSPKFLKTG SHMDLIKSVK PNNIVTMLSA
360 370 380 390 400
GIKEMSLTKY LVSQLMLSND ERMDDLRVFF PNAKNEDWEV ITAGQRVQVI
410 420 430 440 450
KDTEDSKGNL QFGTEVITSD DGTLAALLGA SPGASTAVDI MFDVLQRCYR
460 470 480 490
DEFKGWEPKI KEMVPSFGYR LTDHEDLYHK INEEVTKYLQ VK
Length:492
Mass (Da):54,814
Last modified:May 27, 2015 - v1
Checksum:i0771A20F2DDCA0F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP018629 Genomic DNA Translation: AUS76328.1
CP026962 Genomic DNA Translation: AVG64957.1
LALJ01000001 Genomic DNA Translation: KMR38488.1
LALQ01000013 Genomic DNA Translation: KMR57806.1
LRQH01000056 Genomic DNA Translation: KXA38462.1
UAUZ01000002 Genomic DNA Translation: SQA08667.1
UAVX01000005 Genomic DNA Translation: SQB18238.1
LS483309 Genomic DNA Translation: SQE62365.1
UGZK01000001 Genomic DNA Translation: SUJ51767.1
UHBX01000004 Genomic DNA Translation: SUL31090.1
RefSeqiWP_000211359.1, NZ_UHCQ01000002.1

Genome annotation databases

EnsemblBacteriaiCFG04768; CFG04768; ERS093009_01613
CXE34974; CXE34974; ERS074020_00613
CXL70804; CXL70804; ERS072738_00591
CZQ28235; CZQ28235; ERS1058648_01212
KXA38462; KXA38462; HMPREF3211_00545
OAP78274; OAP78274; A4U86_02620
SCQ98805; SCQ98805; SAMEA2298760_00440
KEGGisaur:SABB_01308
PATRICifig|1280.3350.peg.2302

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP018629 Genomic DNA Translation: AUS76328.1
CP026962 Genomic DNA Translation: AVG64957.1
LALJ01000001 Genomic DNA Translation: KMR38488.1
LALQ01000013 Genomic DNA Translation: KMR57806.1
LRQH01000056 Genomic DNA Translation: KXA38462.1
UAUZ01000002 Genomic DNA Translation: SQA08667.1
UAVX01000005 Genomic DNA Translation: SQB18238.1
LS483309 Genomic DNA Translation: SQE62365.1
UGZK01000001 Genomic DNA Translation: SUJ51767.1
UHBX01000004 Genomic DNA Translation: SUL31090.1
RefSeqiWP_000211359.1, NZ_UHCQ01000002.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCFG04768; CFG04768; ERS093009_01613
CXE34974; CXE34974; ERS074020_00613
CXL70804; CXL70804; ERS072738_00591
CZQ28235; CZQ28235; ERS1058648_01212
KXA38462; KXA38462; HMPREF3211_00545
OAP78274; OAP78274; A4U86_02620
SCQ98805; SCQ98805; SAMEA2298760_00440
KEGGisaur:SABB_01308
PATRICifig|1280.3350.peg.2302

Phylogenomic databases

KOiK00116

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0D3QAJ9_STAAU
AccessioniPrimary (citable) accession number: A0A0D3QAJ9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 7, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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