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Entry version 55 (07 Oct 2020)
Sequence version 1 (29 Apr 2015)
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Protein
Submitted name:

Alanine transaminase

Gene

alaC

Organism
Klebsiella pneumoniae
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminotransferaseImported, Transferase
LigandPyridoxal phosphateARBA annotation, PyruvateImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Alanine transaminaseImported (EC:2.6.1.2Imported)
Submitted name:
AminotransferaseImported
Submitted name:
Glutamate-pyruvate aminotransferase AlaCImported
Submitted name:
LL-diaminopimelate aminotransferaseImported
Submitted name:
PLP-dependent aminotransferase YfdZImported (EC:2.6.1.83Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:alaCImported
Synonyms:dapL_1Imported, dapL_2Imported
ORF Names:B4U21_20615Imported, B4U25_24730Imported, B6R99_05970Imported, BANRA_01070Imported, BANRA_04131Imported, BL124_00010870Imported, BVX91_11915Imported, C3F39_23115Imported, C4Y50_003355Imported, C7V41_12395Imported, DD581_09050Imported, DD583_07910Imported, DM060_20840Imported, DM062_24490Imported, DM078_04515Imported, EAO17_05835Imported, EPB11_06820Imported, EXT45_21035Imported, F0330_27070Imported, F1D54_04630Imported, F3G17_09825Imported, F3G25_02400Imported, FAT93_14465Imported, FCH06_024370Imported, FKC87_15360Imported, FXN60_02565Imported, FXN67_06405Imported, G5637_16645Imported, GF489_01165Imported, GJJ01_16805Imported, GS419_07855Imported, GZH28_01160Imported, NCTC8849_04384Imported, NCTC9637_02218Imported, SAMEA104567806_00915Imported, SAMEA104567846_04150Imported, SAMEA104567853_00266Imported, SAMEA104567906_00177Imported, SAMEA104567925_03591Imported, SAMEA1712987_04231Imported, SAMEA3538702_00264Imported, SAMEA3649466_00470Imported, SAMEA3649709_01068Imported, SAMEA3649772_01632Imported, SAMEA3673122_03979Imported, SAMEA3673128_01616Imported, SAMEA3727630_01460Imported, SAMEA3729660_02889Imported, SAMEA3729780_01421Imported, SAMEA4873575_02596Imported, SAMEA4873581_01401Imported, SAMEA4873632_02285Imported, SK89_03708Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiKlebsiella pneumoniaeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri573 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 375Aminotran_1_2InterPro annotationAdd BLAST339

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K14261

Database of Orthologous Groups

More...
OrthoDBi
417859at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.640.10, 1 hit
3.90.1150.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004839, Aminotransferase_I/II
IPR015424, PyrdxlP-dep_Trfase
IPR015422, PyrdxlP-dep_Trfase_dom1
IPR015421, PyrdxlP-dep_Trfase_major

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00155, Aminotran_1_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53383, SSF53383, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0C7KCY5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAESSPERRF TRIDRLPPYV FNITAELKMA ARRRGEDIID FSMGNPDGAT
60 70 80 90 100
PPHIVEKLCT VAQRPDTHGY STSRGIPRLR RAISRWYEER YNVDIDPESE
110 120 130 140 150
AIVTIGSKEG LAHLMLATLD HGDTVLVPNP SYPIHIYGAV IAGAQVRSVP
160 170 180 190 200
LVEGVDFFNE LERAIRESYP KPKMMILGFP SNPTAQCVEL DFFEKVVALA
210 220 230 240 250
KQYDILVVHD LAYADIVYDG WKAPSIMQVP GARDVAVEFF TLSKSYNMAG
260 270 280 290 300
WRIGFMVGNK TLVNALARIK SYHDYGTFTP LQVAAIAALE GDQQCVRDIA
310 320 330 340 350
EQYKRRRDVL VKGLHEAGWM VECPKASMYV WAKIPEPYAA MGSLEFAKKL
360 370 380 390 400
LNEAKVCVSP GIGFGDYGDT HVRFALIENR DRTRQAIRGI KAMFRADGLL

ASAS
Length:404
Mass (Da):45,121
Last modified:April 29, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i38CD79CF458150D2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP026392 Genomic DNA Translation: AUY21458.1
UJWM02000001 Genomic DNA Translation: CAA1279526.1
VTUL01000119 Genomic DNA Translation: KAA0475539.1
VUBL01000006 Genomic DNA Translation: KAA1507837.1
VWRA01000002 Genomic DNA Translation: KAA5736909.1
VWRE01000007 Genomic DNA Translation: KAA5745395.1
LEUQ01000012 Genomic DNA Translation: KLY15803.1
WJBQ01000001 Genomic DNA Translation: MRD85168.1
WJVL01000011 Genomic DNA Translation: MRJ97609.1
JAAFZD010000001 Genomic DNA Translation: NER53396.1
JAAJRV010000010 Genomic DNA Translation: NGE20380.1
NBSD01001590 Genomic DNA Translation: OWG05621.1
NBIK01000004 Genomic DNA Translation: OXT03988.1
NSMB01000007 Genomic DNA Translation: PAX12952.1
QEFS01002748 Genomic DNA Translation: PVW82441.1
PYBH01000008 Genomic DNA Translation: PWF58860.1
CP043047 Genomic DNA Translation: QEI34252.1
CP047192 Genomic DNA Translation: QHD74091.1
CP043859 Genomic DNA Translation: QHQ42194.1
QOHW01000002 Genomic DNA Translation: RBZ25239.1
QORQ01002524 Genomic DNA Translation: RCI95213.1
QOUF01000612 Genomic DNA Translation: RCJ92794.1
PTFF02000009 Genomic DNA Translation: ROG93235.1
MPYG04000082 Genomic DNA Translation: ROG98233.1
RDAM01000001 Genomic DNA Translation: RRF05754.1
QFMH01000043 Genomic DNA Translation: RXY87347.1
QFMF01000005 Genomic DNA Translation: RXZ11628.1
SGOL01000020 Genomic DNA Translation: RZG32916.1
UGLB01000003 Genomic DNA Translation: STT47305.1
UGLC01000002 Genomic DNA Translation: STT55763.1
UITM01000001 Genomic DNA Translation: SVM80876.1
UIYB01000002 Genomic DNA Translation: SVT03746.1
UJGH01000013 Genomic DNA Translation: SWE24732.1
UJGS01000006 Genomic DNA Translation: SWE79844.1
UJOM01000002 Genomic DNA Translation: SWP32241.1
UJRJ01000008 Genomic DNA Translation: SWU38999.1
UKYO01000001 Genomic DNA Translation: SYM11375.1
STEC01000023 Genomic DNA Translation: THS85153.1
VIAJ01000010 Genomic DNA Translation: TQC90939.1
VSSY01000004 Genomic DNA Translation: TYL81028.1
SUOY02000043 Genomic DNA Translation: TYY77233.1
UNZU01000016 Genomic DNA Translation: VAP09943.1
UWVV01000001 Genomic DNA Translation: VCW53985.1
UWXT01000001 Genomic DNA Translation: VCZ46248.1
CAAGTI010000001 Genomic DNA Translation: VFY99624.1
CAAGVF010000009 Genomic DNA Translation: VGB98873.1
CAAGWD010000003 Genomic DNA Translation: VGC74206.1
CAAGXU010000005 Genomic DNA Translation: VGF24457.1
CAAGXW010000001 Genomic DNA Translation: VGF28245.1
CAAGZV010000004 Genomic DNA Translation: VGH96311.1
CAAHAF010000002 Genomic DNA Translation: VGI22361.1
CAAHCC010000003 Genomic DNA Translation: VGK85037.1
CABGAI010000001 Genomic DNA Translation: VUK64411.1

NCBI Reference Sequences

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RefSeqi
WP_002913372.1, NZ_WYAL01000014.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AIS99745; AIS99745; PMK1_00232
ALR26746; ALR26746; AGG09_21775
SBX84200; SBX84200; SAMEA3531778_01601

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
kpb:FH42_09790
kpne:KU54_007385
kpnu:LI86_07390
kpx:PMK1_00232

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|571.67.peg.3841

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP026392 Genomic DNA Translation: AUY21458.1
UJWM02000001 Genomic DNA Translation: CAA1279526.1
VTUL01000119 Genomic DNA Translation: KAA0475539.1
VUBL01000006 Genomic DNA Translation: KAA1507837.1
VWRA01000002 Genomic DNA Translation: KAA5736909.1
VWRE01000007 Genomic DNA Translation: KAA5745395.1
LEUQ01000012 Genomic DNA Translation: KLY15803.1
WJBQ01000001 Genomic DNA Translation: MRD85168.1
WJVL01000011 Genomic DNA Translation: MRJ97609.1
JAAFZD010000001 Genomic DNA Translation: NER53396.1
JAAJRV010000010 Genomic DNA Translation: NGE20380.1
NBSD01001590 Genomic DNA Translation: OWG05621.1
NBIK01000004 Genomic DNA Translation: OXT03988.1
NSMB01000007 Genomic DNA Translation: PAX12952.1
QEFS01002748 Genomic DNA Translation: PVW82441.1
PYBH01000008 Genomic DNA Translation: PWF58860.1
CP043047 Genomic DNA Translation: QEI34252.1
CP047192 Genomic DNA Translation: QHD74091.1
CP043859 Genomic DNA Translation: QHQ42194.1
QOHW01000002 Genomic DNA Translation: RBZ25239.1
QORQ01002524 Genomic DNA Translation: RCI95213.1
QOUF01000612 Genomic DNA Translation: RCJ92794.1
PTFF02000009 Genomic DNA Translation: ROG93235.1
MPYG04000082 Genomic DNA Translation: ROG98233.1
RDAM01000001 Genomic DNA Translation: RRF05754.1
QFMH01000043 Genomic DNA Translation: RXY87347.1
QFMF01000005 Genomic DNA Translation: RXZ11628.1
SGOL01000020 Genomic DNA Translation: RZG32916.1
UGLB01000003 Genomic DNA Translation: STT47305.1
UGLC01000002 Genomic DNA Translation: STT55763.1
UITM01000001 Genomic DNA Translation: SVM80876.1
UIYB01000002 Genomic DNA Translation: SVT03746.1
UJGH01000013 Genomic DNA Translation: SWE24732.1
UJGS01000006 Genomic DNA Translation: SWE79844.1
UJOM01000002 Genomic DNA Translation: SWP32241.1
UJRJ01000008 Genomic DNA Translation: SWU38999.1
UKYO01000001 Genomic DNA Translation: SYM11375.1
STEC01000023 Genomic DNA Translation: THS85153.1
VIAJ01000010 Genomic DNA Translation: TQC90939.1
VSSY01000004 Genomic DNA Translation: TYL81028.1
SUOY02000043 Genomic DNA Translation: TYY77233.1
UNZU01000016 Genomic DNA Translation: VAP09943.1
UWVV01000001 Genomic DNA Translation: VCW53985.1
UWXT01000001 Genomic DNA Translation: VCZ46248.1
CAAGTI010000001 Genomic DNA Translation: VFY99624.1
CAAGVF010000009 Genomic DNA Translation: VGB98873.1
CAAGWD010000003 Genomic DNA Translation: VGC74206.1
CAAGXU010000005 Genomic DNA Translation: VGF24457.1
CAAGXW010000001 Genomic DNA Translation: VGF28245.1
CAAGZV010000004 Genomic DNA Translation: VGH96311.1
CAAHAF010000002 Genomic DNA Translation: VGI22361.1
CAAHCC010000003 Genomic DNA Translation: VGK85037.1
CABGAI010000001 Genomic DNA Translation: VUK64411.1
RefSeqiWP_002913372.1, NZ_WYAL01000014.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAIS99745; AIS99745; PMK1_00232
ALR26746; ALR26746; AGG09_21775
SBX84200; SBX84200; SAMEA3531778_01601
KEGGikpb:FH42_09790
kpne:KU54_007385
kpnu:LI86_07390
kpx:PMK1_00232
PATRICifig|571.67.peg.3841

Phylogenomic databases

KOiK14261
OrthoDBi417859at2

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 1 hit
InterProiView protein in InterPro
IPR004839, Aminotransferase_I/II
IPR015424, PyrdxlP-dep_Trfase
IPR015422, PyrdxlP-dep_Trfase_dom1
IPR015421, PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155, Aminotran_1_2, 1 hit
SUPFAMiSSF53383, SSF53383, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0C7KCY5_KLEPN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0C7KCY5
Secondary accession number(s): A0A0J2GQD9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2015
Last sequence update: April 29, 2015
Last modified: October 7, 2020
This is version 55 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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