Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 51 (02 Jun 2021)
Sequence version 1 (29 Apr 2015)
Previous versions | rss
Add a publicationFeedback
Protein

Peptide deformylase

Gene

def

Organism
Haemophilus influenzae
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi91IronUniRule annotation1
Metal bindingi133IronUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei134UniRule annotation1
Metal bindingi137IronUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseUniRule annotationImported
Biological processProtein biosynthesisUniRule annotation
LigandIronUniRule annotation, Metal-bindingUniRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Peptide deformylaseUniRule annotationARBA annotation (EC:3.5.1.88UniRule annotation)
Short name:
PDFUniRule annotation
Alternative name(s):
Polypeptide deformylaseUniRule annotationARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:defUniRule annotationImported
ORF Names:BV064_00630Imported, BVZ80_01894Imported, CH609_06905Imported, CH620_09290Imported, CH627_09575Imported, DLJ98_06980Imported, F8B64_02145Imported, FRB14_09340Imported, JPHIA_04000Imported, NCTC11873_00460Imported, NTHI1209_00143Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaemophilus influenzaeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri727 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000516418 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000326589 Componenti: Chromosome
  • UP000238283 Componenti: Unassembled WGS sequence
  • UP000319073 Componenti: Unassembled WGS sequence
  • UP000246568 Componenti: Chromosome
  • UP000260851 Componenti: Unassembled WGS sequence
  • UP000278034 Componenti: Chromosome 1
  • UP000261131 Componenti: Unassembled WGS sequence
  • UP000260888 Componenti: Unassembled WGS sequence
  • UP000237959 Componenti: Unassembled WGS sequence
  • UP000050700 Componenti: Unassembled WGS sequence

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the polypeptide deformylase family.UniRule annotationARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00487, Pep_deformylase, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.45.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00163, Pep_deformylase, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023635, Peptide_deformylase
IPR036821, Peptide_deformylase_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10458, PTHR10458, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01327, Pep_deformylase, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF004749, Pep_def, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01576, PDEFORMYLASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56420, SSF56420, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00079, pept_deformyl, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0C5F371-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTALNVLIYP DDHLKVVCEP VTEVNDAIRK IVDDMFDTMY QEKGIGLAAP
60 70 80 90 100
QVDILQRIIT IDVEGDKQNQ FVLINPEILA SEGETGIEEG CLSIPGFRAL
110 120 130 140 150
VPRKEKVTVR ALDRDGKEFT LDADGLLAIC IQHEIDHLNG ILFVDYLSPL
160
KRQRIKEKLI KYKKQIAKS
Length:169
Mass (Da):19,058
Last modified:April 29, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7040E05554F738CD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP029620 Genomic DNA Translation: AWP54319.1
AP022846 Genomic DNA Translation: BCB15500.1
JMQP01000001 Genomic DNA Translation: KIS36721.1
NDZR01000282 Genomic DNA Translation: PRI68186.1
NEBH01000021 Genomic DNA Translation: PRJ32017.1
CP044497 Genomic DNA Translation: QFG54886.1
QVJI01000021 Genomic DNA Translation: RFN62370.1
QVIT01000016 Genomic DNA Translation: RFN65436.1
QVJU01000004 Genomic DNA Translation: RFO34881.1
VOFR01000014 Genomic DNA Translation: TWU89700.1
LR134490 Genomic DNA Translation: VEI54072.1

NCBI Reference Sequences

More...
RefSeqi
WP_005630900.1, NZ_VOFX01000019.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
KIS36721; KIS36721; NTHI1209_00143
PRI68186; PRI68186; BVZ80_01894
PRJ32017; PRJ32017; BV064_00630
PRL49732; PRL49732; BV080_01073
RFN62370; RFN62370; CH627_09575
RFN65436; RFN65436; CH620_09290
RFO34881; RFO34881; CH609_06905
VEI54072; VEI54072; NCTC11873_00460

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56844333

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hic:NTHIC486_00383
hih:NF38_02060
hiw:NTHI477_01714
hix:NTHI723_01101

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|727.529.peg.1659

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP029620 Genomic DNA Translation: AWP54319.1
AP022846 Genomic DNA Translation: BCB15500.1
JMQP01000001 Genomic DNA Translation: KIS36721.1
NDZR01000282 Genomic DNA Translation: PRI68186.1
NEBH01000021 Genomic DNA Translation: PRJ32017.1
CP044497 Genomic DNA Translation: QFG54886.1
QVJI01000021 Genomic DNA Translation: RFN62370.1
QVIT01000016 Genomic DNA Translation: RFN65436.1
QVJU01000004 Genomic DNA Translation: RFO34881.1
VOFR01000014 Genomic DNA Translation: TWU89700.1
LR134490 Genomic DNA Translation: VEI54072.1
RefSeqiWP_005630900.1, NZ_VOFX01000019.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiKIS36721; KIS36721; NTHI1209_00143
PRI68186; PRI68186; BVZ80_01894
PRJ32017; PRJ32017; BV064_00630
PRL49732; PRL49732; BV080_01073
RFN62370; RFN62370; CH627_09575
RFN65436; RFN65436; CH620_09290
RFO34881; RFO34881; CH609_06905
VEI54072; VEI54072; NCTC11873_00460
GeneIDi56844333
KEGGihic:NTHIC486_00383
hih:NF38_02060
hiw:NTHI477_01714
hix:NTHI723_01101
PATRICifig|727.529.peg.1659

Family and domain databases

CDDicd00487, Pep_deformylase, 1 hit
Gene3Di3.90.45.10, 1 hit
HAMAPiMF_00163, Pep_deformylase, 1 hit
InterProiView protein in InterPro
IPR023635, Peptide_deformylase
IPR036821, Peptide_deformylase_sf
PANTHERiPTHR10458, PTHR10458, 1 hit
PfamiView protein in Pfam
PF01327, Pep_deformylase, 1 hit
PIRSFiPIRSF004749, Pep_def, 1 hit
PRINTSiPR01576, PDEFORMYLASE
SUPFAMiSSF56420, SSF56420, 1 hit
TIGRFAMsiTIGR00079, pept_deformyl, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0C5F371_HAEIF
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0C5F371
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2015
Last sequence update: April 29, 2015
Last modified: June 2, 2021
This is version 51 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again