UniProtKB - A0A0C4WPR0 (A0A0C4WPR0_9GAMM)
Sec-independent protein translocase protein TatA
tatA
Functioni
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
UniRule annotationGO - Molecular functioni
- protein transmembrane transporter activity Source: UniProtKB-UniRule
GO - Biological processi
- protein transport by the Tat complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, TranslocationUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Sec-independent protein translocase protein TatAUniRule annotation |
Gene namesi | Name:tatAUniRule annotationImported ORF Names:Achr_6430Imported |
Organismi | Azotobacter chroococcum NCIMB 8003Imported |
Taxonomic identifieri | 1328314 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Azotobacter › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation
Plasma Membrane
- integral component of plasma membrane Source: UniProtKB-UniRule
- TAT protein transport complex Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 24 | HelicalUniRule annotationAdd BLAST | 19 |
Keywords - Cellular componenti
Cell membraneUniRule annotation, MembraneInteractioni
Subunit structurei
The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.
UniRule annotationProtein-protein interaction databases
STRINGi | 1328314.Achr_6430 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 45 – 77 | DisorderedSequence analysisAdd BLAST | 33 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 62 – 77 | Basic and acidic residuesSequence analysisAdd BLAST | 16 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
HOGENOMi | CLU_086034_5_1_6 |
OrthoDBi | 1907955at2 |
Family and domain databases
HAMAPi | MF_00236, TatA_E, 1 hit |
InterProi | View protein in InterPro IPR003369, TatA/B/E IPR006312, TatA/E |
Pfami | View protein in Pfam PF02416, TatA_B_E, 1 hit |
TIGRFAMsi | TIGR01411, tatAE, 1 hit |
i Sequence
Sequence statusi: Complete.
10 20 30 40 50
MGFGGISIWQ LLIILLIVVM LFGTKRLKSL GSDLGDAIKG FRKSMDNEEN
60 70
KAPPVEEQKG QTIEAQARKV EEPARKD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP010415 Genomic DNA Translation: AJE20142.1 |
RefSeqi | WP_039801821.1, NZ_CP010415.1 |
Genome annotation databases
EnsemblBacteriai | AJE20142; AJE20142; Achr_6430 |
GeneIDi | 61929687 |
KEGGi | acx:Achr_6430 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP010415 Genomic DNA Translation: AJE20142.1 |
RefSeqi | WP_039801821.1, NZ_CP010415.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 1328314.Achr_6430 |
Genome annotation databases
EnsemblBacteriai | AJE20142; AJE20142; Achr_6430 |
GeneIDi | 61929687 |
KEGGi | acx:Achr_6430 |
Phylogenomic databases
HOGENOMi | CLU_086034_5_1_6 |
OrthoDBi | 1907955at2 |
Family and domain databases
HAMAPi | MF_00236, TatA_E, 1 hit |
InterProi | View protein in InterPro IPR003369, TatA/B/E IPR006312, TatA/E |
Pfami | View protein in Pfam PF02416, TatA_B_E, 1 hit |
TIGRFAMsi | TIGR01411, tatAE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0C4WPR0_9GAMM | |
Accessioni | A0A0C4WPR0Primary (citable) accession number: A0A0C4WPR0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 29, 2015 |
Last sequence update: | April 29, 2015 | |
Last modified: | January 19, 2022 | |
This is version 28 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |