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Protein
Submitted name:

Hepatitis B virus x interacting protein

Gene

LAMTOR5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatitis B virus x interacting proteinImported
Submitted name:
Ragulator complex protein LAMTOR5Imported
Gene namesi
Name:LAMTOR5Imported
Synonyms:HBXIPImported
ORF Names:hCG_40252Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000134248.13
HGNCiHGNC:17955 LAMTOR5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134248

Expressioni

Gene expression databases

BgeeiENSG00000134248 Expressed in 224 organ(s), highest expression level in nephron tubule

Interactioni

Binary interactionsi

Protein-protein interaction databases

IntActiA0A0C4DGV4, 7 interactors
A0A0C4DGV4, 7 interactors

Structurei

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IZVH Eukaryota
ENOG4111WFD LUCA
GeneTreeiENSGT00390000006247
KOiK16344
OrthoDBiEOG091G18B1

Family and domain databases

InterProiView protein in InterPro
IPR024135 LAMTOR5
PANTHERiPTHR13342 PTHR13342, 1 hit
PfamiView protein in Pfam
PF16672 LAMTOR5, 1 hit
PRINTSiPR02092 HEPBVIRUSXIP

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A0C4DGV4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPGAGHLDG HRAGSPSLRQ ALCDGSAVMF SSKERGRCTV INFVPLEAPL
60 70 80 90 100
RSTPRSRQVT EACGGEGRAV PLGSEPEWSV GGMEATLEQH LEDTMKNPSI
110 120 130 140 150
VGVLCTDSQG LNLGCRGTLS DEHAGVISVL AQQAAKLTSD PTDIPVVCLE
160 170
SDNGNIMIQK HDGITVAVHK MAS
Length:173
Mass (Da):18,159
Last modified:April 1, 2015 - v1
Checksum:i75B3AA133363A336
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43504LTOR5_HUMAN
Ragulator complex protein LAMTOR5
LAMTOR5 HBXIP, XIP
91Annotation score:
R4GMU8R4GMU8_HUMAN
Ragulator complex protein LAMTOR5
LAMTOR5
79Annotation score:
E9PLX3E9PLX3_HUMAN
Ragulator complex protein LAMTOR5
LAMTOR5
90Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL390797 Genomic DNA No translation available.
CH471122 Genomic DNA Translation: EAW56447.1
RefSeqiNP_006393.2, NM_006402.2
UniGeneiHs.439815

Genome annotation databases

EnsembliENST00000256644; ENSP00000256644; ENSG00000134248
ENST00000614544; ENSP00000480529; ENSG00000134248
GeneIDi10542
KEGGihsa:10542

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL390797 Genomic DNA No translation available.
CH471122 Genomic DNA Translation: EAW56447.1
RefSeqiNP_006393.2, NM_006402.2
UniGeneiHs.439815

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6B9XX-ray1.42E1-173[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA0A0C4DGV4, 7 interactors
A0A0C4DGV4, 7 interactors

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000256644; ENSP00000256644; ENSG00000134248
ENST00000614544; ENSP00000480529; ENSG00000134248
GeneIDi10542
KEGGihsa:10542

Organism-specific databases

CTDi10542
EuPathDBiHostDB:ENSG00000134248.13
HGNCiHGNC:17955 LAMTOR5
OpenTargetsiENSG00000134248
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IZVH Eukaryota
ENOG4111WFD LUCA
GeneTreeiENSGT00390000006247
KOiK16344
OrthoDBiEOG091G18B1

Miscellaneous databases

ChiTaRSiLAMTOR5 human
GenomeRNAii10542

Gene expression databases

BgeeiENSG00000134248 Expressed in 224 organ(s), highest expression level in nephron tubule

Family and domain databases

InterProiView protein in InterPro
IPR024135 LAMTOR5
PANTHERiPTHR13342 PTHR13342, 1 hit
PfamiView protein in Pfam
PF16672 LAMTOR5, 1 hit
PRINTSiPR02092 HEPBVIRUSXIP
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0C4DGV4_HUMAN
AccessioniPrimary (citable) accession number: A0A0C4DGV4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: November 7, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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