UniProtKB - A0A0C4DGM5 (A0A0C4DGM5_HUMAN)
Protein
Submitted name:
Zinc finger protein 106
Gene
ZNF106
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 106ImportedSubmitted name: Zinc finger protein 106 homolog (Mouse), isoform CRA_cImported |
Gene namesi | ORF Names:hCG_40432Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000103994.16 |
HGNCi | HGNC:12886, ZNF106 |
Expressioni
Gene expression databases
Bgeei | ENSG00000103994, Expressed in quadriceps femoris and 245 other tissues |
ExpressionAtlasi | A0A0C4DGM5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 712 – 1000 | WD_REPEATS_REGIONInterPro annotationAdd BLAST | 289 | |
Repeati | 712 – 751 | WDPROSITE-ProRule annotationAdd BLAST | 40 | |
Repeati | 752 – 796 | WDPROSITE-ProRule annotationAdd BLAST | 45 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 97 – 130 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 143 – 167 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 182 – 233 | DisorderedSequence analysisAdd BLAST | 52 | |
Regioni | 306 – 328 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 367 – 403 | DisorderedSequence analysisAdd BLAST | 37 | |
Regioni | 437 – 668 | DisorderedSequence analysisAdd BLAST | 232 | |
Regioni | 687 – 712 | DisorderedSequence analysisAdd BLAST | 26 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 443 – 457 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 458 – 501 | PolarSequence analysisAdd BLAST | 44 | |
Compositional biasi | 587 – 606 | PolyampholyteSequence analysisAdd BLAST | 20 | |
Compositional biasi | 625 – 639 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 640 – 668 | PolarSequence analysisAdd BLAST | 29 |
Keywords - Domaini
WD repeatPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000157336 |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf IPR042622, Znf106 IPR013087, Znf_C2H2_type |
PANTHERi | PTHR14435, PTHR14435, 1 hit |
Pfami | View protein in Pfam PF00400, WD40, 2 hits |
SMARTi | View protein in SMART SM00320, WD40, 6 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 2 hits PS50294, WD_REPEATS_REGION, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
A0A0C4DGM5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVPLVQNEQE ALDLDGEPDL SSLEGFQWEG VSISSSPGLA RKRSLSESSV
60 70 80 90 100
IMDRAPSVYS FFSEEGTGKE NEPQQMVSPS NSLRAGQSQK ATMHLKQEVT
110 120 130 140 150
PRAASLRTGE RAENVATQRR HSAQLSSDHI IPLMHLAKDL NSQERSIPPS
160 170 180 190 200
ENQNSQESNG EGNCLSSSAS SALAISSLAD AATDSSCTSG AEQNDGQSIR
210 220 230 240 250
KKRRATGDGS SPELPSLERK NKRRKIKGKK ERSQVDQLLN ISLREEELSK
260 270 280 290 300
SLQCMDNNLL QARAALQTAY VEVQRLLMLK QQITMEMSAL RTHRIQILQG
310 320 330 340 350
LQETYEPSEH PDQVPCSLTR ERRNSRSQTS IDAALLPTPF FPLFLEPPSS
360 370 380 390 400
HVSPSPTGAS LQITTSPTFQ THGSVPAPDS SVQIKQEPMS PEQDENVNAV
410 420 430 440 450
PPSSACNVSK ELLEANREIS DSCPVYPVIT ARLSLPESTE SFHEPSQELK
460 470 480 490 500
FSVEQRNTRN RENSPSSQSA GLSSINKEGE EPTKGNSGSE ACTSSFLRLS
510 520 530 540 550
FASETPLEKE PHSPADQPEQ QAESTLTSAE TRGSKKKKKL RKKKSLRAAH
560 570 580 590 600
VPENSDTEQD VLTVKPVRKV KAGKLIKGGK VTTSTWEDSR TGREQESVRD
610 620 630 640 650
EPDSDSSLEV LEIPNPQLEV VAIDSSESGE EKPDSPSKKD IWNSTEQNPL
660 670 680 690 700
ETSRSGCDEV SSTSEIGTRY KDGIPVSVAE TQTVISSIKG SKNSSEISSE
710 720 730 740 750
PGDDDEPTEG SFEGHQAAVN AIQIFGNLLY TCSADKTVRV YNLVSRKCIG
760 770 780 790 800
VFEGHTSKVN CLLVTQTSGK NAALYTGSSD HTIRCYNVKS RECVEQLQLE
810 820 830 840 850
DRVLCLHSRW RILYAGLANG TVVTFNIKNN KRLEIFECHG PRAVSCLATA
860 870 880 890 900
QEGARKLLVV GSYDCTISVR DARNGLLLRT LEGHSKTILC MKVVNDLVFS
910 920 930 940 950
GSSDQSVHAH NIHTGELVRI YKGHNHAVTV VNILGKVMVT ACLDKFVRVY
960 970 980 990 1000
ELQSHDRLQV YGGHKDMIMC MTIHKSMIYT GCYDGSIQAV RLNLMQNYRC
1010 1020 1030 1040 1050
WWHGCSLIFG VVDHLKQHLL TDHTNPNFQT LKCRWKNCDA FFTARKGSKQ
1060
DAAGHIERHA EDDSKIDS
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9H2Y7 | ZN106_HUMAN | Zinc finger protein 106 | ZNF106 SH3BP3, ZFP106, ZNF474 | 1,883 | Annotation score: | ||
H3BSS6 | H3BSS6_HUMAN | Zinc finger protein 106 | ZNF106 | 1,906 | Annotation score: | ||
H3BS99 | H3BS99_HUMAN | Zinc finger protein 106 | ZNF106 | 850 | Annotation score: | ||
H3BNJ4 | H3BNJ4_HUMAN | Zinc finger protein 106 | ZNF106 | 201 | Annotation score: | ||
H3BNX5 | H3BNX5_HUMAN | Zinc finger protein 106 | ZNF106 | 816 | Annotation score: | ||
U3KQH7 | U3KQH7_HUMAN | Zinc finger protein 106 | ZNF106 | 191 | Annotation score: | ||
H3BRD4 | H3BRD4_HUMAN | Zinc finger protein 106 | ZNF106 | 217 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012651 Genomic DNA No translation available. AC018362 Genomic DNA No translation available. CH471125 Genomic DNA Translation: EAW92553.1 |
RefSeqi | NP_001271235.1, NM_001284306.1 |
Genome annotation databases
Ensembli | ENST00000565611; ENSP00000457637; ENSG00000103994 |
GeneIDi | 64397 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012651 Genomic DNA No translation available. AC018362 Genomic DNA No translation available. CH471125 Genomic DNA Translation: EAW92553.1 |
RefSeqi | NP_001271235.1, NM_001284306.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 10821, 90 antibodies |
Genome annotation databases
Ensembli | ENST00000565611; ENSP00000457637; ENSG00000103994 |
GeneIDi | 64397 |
Organism-specific databases
CTDi | 64397 |
EuPathDBi | HostDB:ENSG00000103994.16 |
HGNCi | HGNC:12886, ZNF106 |
OpenTargetsi | ENSG00000103994 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157336 |
Miscellaneous databases
BioGRID-ORCSi | 64397, 10 hits in 849 CRISPR screens |
ChiTaRSi | ZNF106, human |
GenomeRNAii | 64397 |
Gene expression databases
Bgeei | ENSG00000103994, Expressed in quadriceps femoris and 245 other tissues |
ExpressionAtlasi | A0A0C4DGM5, baseline and differential |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf IPR042622, Znf106 IPR013087, Znf_C2H2_type |
PANTHERi | PTHR14435, PTHR14435, 1 hit |
Pfami | View protein in Pfam PF00400, WD40, 2 hits |
SMARTi | View protein in SMART SM00320, WD40, 6 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 2 hits PS50294, WD_REPEATS_REGION, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0C4DGM5_HUMAN | |
Accessioni | A0A0C4DGM5Primary (citable) accession number: A0A0C4DGM5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 1, 2015 |
Last sequence update: | April 1, 2015 | |
Last modified: | December 2, 2020 | |
This is version 51 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |