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Protein
Submitted name:

Serine/threonine-protein kinase 35

Gene

STK35

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase 35Imported
Gene namesi
Name:STK35Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000125834.12
HGNCiHGNC:16254 STK35

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000125834

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0C4DGC9

Expressioni

Gene expression databases

BgeeiENSG00000125834 Expressed in 208 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiA0A0C4DGC9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0C4DGC9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 391Protein kinaseInterPro annotationAdd BLAST329

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0595 Eukaryota
ENOG410XR01 LUCA
GeneTreeiENSGT00880000137951

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0C4DGC9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GARRGTQSPE RKRRSPVPRA PSTKLRPAAA ARAMDPVAAE APGEAFLARR
60 70 80 90 100
RPEGGGGSAR PRYSLLAEIG RGSYGVVYEA VAGRSGARVA VKKIRCDAPE
110 120 130 140 150
NVELALAEFW ALTSLKRRHQ NVVQFEECVL QRNGLAQRMS HGNKSSQLYL
160 170 180 190 200
RLVETSLKGE RILGYAEEPC YLWFVMEFCE GGDLNQYVLS RRPDPATNKS
210 220 230 240 250
FMLQLTSAIA FLHKNHIVHR DLKPDNILIT ERSGTPILKV ADFGLSKVCA
260 270 280 290 300
GLAPRGKEGN QDNKNVNVNK YWLSSACGSD FYMAPEVWEG HYTAKADIFA
310 320 330 340 350
LGIIIWAMIE RITFIDSETK KELLGTYIKQ GTEIVPVGEA LLENPKMELH
360 370 380 390
IPQKRRTSMS EGIKQLLKDM LAANPQDRPD AFELETRMDQ VTCAA
Length:395
Mass (Da):43,911
Last modified:April 1, 2015 - v1
Checksum:iE9F3720F05F729D4
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8TDR2STK35_HUMAN
Serine/threonine-protein kinase 35
STK35 CLIK1, PDIK1, STK35L1
534Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121899 Genomic DNA No translation available.
AL359916 Genomic DNA No translation available.
UniGeneiHs.100057

Genome annotation databases

EnsembliENST00000493263; ENSP00000426612; ENSG00000125834

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121899 Genomic DNA No translation available.
AL359916 Genomic DNA No translation available.
UniGeneiHs.100057

3D structure databases

ProteinModelPortaliA0A0C4DGC9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A0C4DGC9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000493263; ENSP00000426612; ENSG00000125834

Organism-specific databases

EuPathDBiHostDB:ENSG00000125834.12
HGNCiHGNC:16254 STK35
OpenTargetsiENSG00000125834
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0595 Eukaryota
ENOG410XR01 LUCA
GeneTreeiENSGT00880000137951

Miscellaneous databases

ChiTaRSiSTK35 human

Gene expression databases

BgeeiENSG00000125834 Expressed in 208 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiA0A0C4DGC9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0C4DGC9_HUMAN
AccessioniPrimary (citable) accession number: A0A0C4DGC9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: November 7, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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