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Protein
Submitted name:

Acyl-coenzyme A oxidase-like protein

Gene

ACOXL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Acyl-coenzyme A oxidase-like proteinImported
Gene namesi
Name:ACOXLImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000153093.18
HGNCiHGNC:25621 ACOXL

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000153093

PTM / Processingi

Proteomic databases

PaxDbiA0A0C4DG10

Expressioni

Gene expression databases

BgeeiENSG00000153093 Expressed in 89 organ(s), highest expression level in visceral pleura
ExpressionAtlasiA0A0C4DG10 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000407761

Structurei

3D structure databases

ProteinModelPortaliA0A0C4DG10
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 196Acyl-CoA_dh_1InterPro annotationAdd BLAST131
Domaini243 – 352ACOXInterPro annotationAdd BLAST110

Phylogenomic databases

eggNOGiKOG0135 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00530000062919

Family and domain databases

InterProiView protein in InterPro
IPR002655 Acyl-CoA_oxidase_C
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF01756 ACOX, 1 hit
PF00441 Acyl-CoA_dh_1, 1 hit
SUPFAMiSSF47203 SSF47203, 2 hits
SSF56645 SSF56645, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A0C4DG10-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
RDENGSLYPG VTAIDMMYKE GLHGVDNGIL IFDKVRIPRE NLLDKFGSVA
60 70 80 90 100
PDGQYHSPIR NKSARFNAML AALTPSRLAV AFQAMGAMKL GLTIAIRYSH
110 120 130 140 150
SRRQFGPKTK EEVKIIEHQT QTLRLMPHLA TALALTFVSR YAGALLDEDV
160 170 180 190 200
FQGKELVNSR SLQALVAGLK AYSTWENIRC LQDCRECTGG MVVGRELLAQ
210 220 230 240 250
YTKQYEEKPL FGLLQNWAES VGDKLRTSFL AFNMDTVDDL AFLLKAVKFR
260 270 280 290 300
ERVLQRGLVA RIYYKVKTKK EDFFHAWNSC LHHVASLSLA HTHRVTLEQF
310 320 330 340 350
SLAVKSCPDQ EDQTLLMKFC LLYGTKLVFQ ERAWYLEHKY LTPMASTRIR

NQERC
Length:355
Mass (Da):40,504
Last modified:April 1, 2015 - v1
Checksum:i0A0F68B30EE01DFF
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NUZ1ACOXL_HUMAN
Acyl-coenzyme A oxidase-like protei...
ACOXL
547Annotation score:
H7C0A6H7C0A6_HUMAN
Acyl-coenzyme A oxidase-like protei...
ACOXL
93Annotation score:
H7C2M3H7C2M3_HUMAN
Acyl-coenzyme A oxidase-like protei...
ACOXL
161Annotation score:
H7C345H7C345_HUMAN
Acyl-coenzyme A oxidase-like protei...
ACOXL
106Annotation score:
C9JQI3C9JQI3_HUMAN
Acyl-coenzyme A oxidase-like protei...
ACOXL
70Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC023131 Genomic DNA No translation available.
AC096591 Genomic DNA No translation available.
AC096670 Genomic DNA No translation available.
AC114776 Genomic DNA No translation available.
UniGeneiHs.253320

Genome annotation databases

EnsembliENST00000417074; ENSP00000387832; ENSG00000153093

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC023131 Genomic DNA No translation available.
AC096591 Genomic DNA No translation available.
AC096670 Genomic DNA No translation available.
AC114776 Genomic DNA No translation available.
UniGeneiHs.253320

3D structure databases

ProteinModelPortaliA0A0C4DG10
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000407761

Proteomic databases

PaxDbiA0A0C4DG10

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000417074; ENSP00000387832; ENSG00000153093

Organism-specific databases

EuPathDBiHostDB:ENSG00000153093.18
HGNCiHGNC:25621 ACOXL
OpenTargetsiENSG00000153093
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0135 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00530000062919

Miscellaneous databases

ChiTaRSiACOXL human

Gene expression databases

BgeeiENSG00000153093 Expressed in 89 organ(s), highest expression level in visceral pleura
ExpressionAtlasiA0A0C4DG10 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002655 Acyl-CoA_oxidase_C
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF01756 ACOX, 1 hit
PF00441 Acyl-CoA_dh_1, 1 hit
SUPFAMiSSF47203 SSF47203, 2 hits
SSF56645 SSF56645, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0C4DG10_HUMAN
AccessioniPrimary (citable) accession number: A0A0C4DG10
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: September 12, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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