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Protein
Submitted name:

Forkhead box P3, isoform CRA_b

Gene

FOXP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi287 – 433Fork-headPROSITE-ProRule annotationAdd BLAST147

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box P3, isoform CRA_bImported
Submitted name:
Forkhead box protein P3Imported
Gene namesi
Name:FOXP3Imported
ORF Names:hCG_19830Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000049768.14
HGNCiHGNC:6106 FOXP3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000049768

Expressioni

Gene expression databases

BgeeiENSG00000049768

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini287 – 433Fork-headInterPro annotationAdd BLAST147

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili189 – 209Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4385 Eukaryota
COG5025 LUCA
GeneTreeiENSGT00920000148947

Family and domain databases

Gene3Di1.10.10.10, 2 hits
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR032354 FOXP-CC
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00250 Forkhead, 2 hits
PF16159 FOXP-CC, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 2 hits
PROSITEiView protein in PROSITE
PS50039 FORK_HEAD_3, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0C4DFW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPISGASPS WRAAPKASDL LGARGPGGTF QGRDLRGGAH ASSSSLNPMP
60 70 80 90 100
PSQLQLSTVD AHARTPVLQV HPLESPAMIS LTPPTTATGV FSLKARPGLP
110 120 130 140 150
PGINVASLEW VSREPALLCT FPNPSAPRKD STLSAVPQSS YPLLANGVCK
160 170 180 190 200
WPGCEKVFEE PEDFLKHCQA DHLLDEKGRA QCLLQREMVQ SLEQQLVLEK
210 220 230 240 250
EKLSAMQAHL AGKMALTKAS SVASSDKGSC CIVAAGSQGP VVPAWSGPRE
260 270 280 290 300
APDSLFAVRR HLWGSHGNST FPEFLHNMDY FKFHNMRPPF TYATLIRWAI
310 320 330 340 350
LEAPEKQRTL NEIYHWFTRM FAFFRNHPAT WKVSSSEVAV TGMASSAIAA
360 370 380 390 400
QSGQAWVWAH RHIGEERDVG CWWWLLASEV DAHLLPVPGL PQNAIRHNLS
410 420 430 440
LHKCFVRVES EKGAVWTVDE LEFRKKRSQR PSRCSNPTPG P
Length:441
Mass (Da):48,405
Last modified:April 1, 2015 - v1
Checksum:iDDCA514D6801B549
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC232271 Genomic DNA No translation available.
CH471224 Genomic DNA Translation: EAW50672.1
UniGeneiHs.247700

Genome annotation databases

EnsembliENST00000376197; ENSP00000365369; ENSG00000049768

Similar proteinsi

Entry informationi

Entry nameiA0A0C4DFW6_HUMAN
AccessioniPrimary (citable) accession number: A0A0C4DFW6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: July 18, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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