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Entry version 57 (07 Apr 2021)
Sequence version 1 (01 Apr 2015)
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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Listeria monocytogenes
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotationARBA annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseUniRule annotationImportedARBA annotation
Biological processProtein biosynthesisUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotationARBA annotation (EC:2.1.2.9UniRule annotationARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fmtUniRule annotation
ORF Names:A8N58_04875Imported, ACY06_07795Imported, AF314_05530Imported, AMC55_07235Imported, APE37_08670Imported, ARS65_05320Imported, B1N06_03890Imported, B1N70_01115Imported, B4Y49_08390Imported, BBW72_05860Imported, D9T24_10650Imported, DU018_00245Imported, EPI21_06295Imported, EXZ73_01495Imported, F6515_00120Imported, FA835_01040Imported, FDP75_04175Imported, FLQ91_04320Imported, FLQ96_03080Imported, FLR03_05485Imported, KW30_09770Imported, LH97_05920Imported, LmNIHS28_01424Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiListeria monocytogenesImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1639 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000489121 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000335574 Componenti: Unassembled WGS sequence
  • UP000032903 Componenti: Unassembled WGS sequence
  • UP000331186 Componenti: Unassembled WGS sequence
  • UP000329913 Componenti: Unassembled WGS sequence
  • UP000423131 Componenti: Unassembled WGS sequence
  • UP000339188 Componenti: Unassembled WGS sequence
  • UP000406273 Componenti: Unassembled WGS sequence
  • UP000332723 Componenti: Unassembled WGS sequence
  • UP000376505 Componenti: Unassembled WGS sequence
  • UP000356934 Componenti: Unassembled WGS sequence
  • UP000333288 Componenti: Unassembled WGS sequence
  • UP000364783 Componenti: Unassembled WGS sequence
  • UP000401854 Componenti: Unassembled WGS sequence
  • UP000479018 Componenti: Unassembled WGS sequence
  • UP000330669 Componenti: Unassembled WGS sequence
  • UP000345051 Componenti: Unassembled WGS sequence
  • UP000474379 Componenti: Unassembled WGS sequence
  • UP000380942 Componenti: Unassembled WGS sequence
  • UP000430697 Componenti: Unassembled WGS sequence
  • UP000414325 Componenti: Unassembled WGS sequence
  • UP000410967 Componenti: Unassembled WGS sequence
  • UP000431657 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 179Formyl_trans_NInterPro annotationAdd BLAST177
Domaini203 – 300Formyl_trans_CInterPro annotationAdd BLAST98

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni109 – 112Tetrahydrofolate (THF) bindingUniRule annotation4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Fmt family.UniRule annotationARBA annotation

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
2009156at2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08646, FMT_core_Met-tRNA-FMT_N, 1 hit
cd08704, Met_tRNA_FMT_C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.10.25.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00182, Formyl_trans, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005794, Fmt
IPR005793, Formyl_trans_C
IPR037022, Formyl_trans_C_sf
IPR002376, Formyl_transf_N
IPR036477, Formyl_transf_N_sf
IPR011034, Formyl_transferase-like_C_sf
IPR001555, GART_AS
IPR044135, Met-tRNA-FMT_C
IPR041711, Met-tRNA-FMT_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02911, Formyl_trans_C, 1 hit
PF00551, Formyl_trans_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50486, SSF50486, 1 hit
SSF53328, SSF53328, 1 hit

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR00460, fmt, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00373, GART, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0B8R964-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKIIFMGTP EFSVPVLTQL ASTYDVVAVV TQPDRPVGRK RVLTPPPVKK
60 70 80 90 100
AALELAIPVY QPEKLRTSSE LEELIALEAD LLVTAAYGQI LPNSLLESPK
110 120 130 140 150
HGAINVHASL LPEYRGGAPV HYALLDGKTE TGVTIMYMVE KLDAGDMISQ
160 170 180 190 200
RKIPITDEDN TGTMFDKLSK LGAELLMDTL PDFLAGKITA IPQDPEKVTF
210 220 230 240 250
ARNISREQEK IDWTKPGRTI FNQIRGLSPW PVAYTTLEEK PFKIWEATYE
260 270 280 290 300
ETKEDGEPGA ILADKTTLKI VAGDGTLIVP TVIQPAGKPK MDVHSFMTGA
310
GRNLSKTTRF GE
Length:312
Mass (Da):34,243
Last modified:April 1, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64B9D43A66AD0CF0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAAAGF010000003 Genomic DNA Translation: EAA0410767.1
AAAIVD010000003 Genomic DNA Translation: EAC5360770.1
AAAJKI010000001 Genomic DNA Translation: EAC6546782.1
AAAJSR010000004 Genomic DNA Translation: EAC7205032.1
AAAKRK010000005 Genomic DNA Translation: EAC9135143.1
AAAKTU010000002 Genomic DNA Translation: EAC9323174.1
AAAKVJ010000003 Genomic DNA Translation: EAC9449867.1
AAALCR010000002 Genomic DNA Translation: EAD0028589.1
AAAMQP010000004 Genomic DNA Translation: EAD3171154.1
AAANOM010000004 Genomic DNA Translation: EAD4984249.1
AAANYN010000002 Genomic DNA Translation: EAD5772953.1
AAAPCL010000003 Genomic DNA Translation: EAD8127817.1
AAAPKJ010000002 Genomic DNA Translation: EAD8746263.1
AAAQFV010000003 Genomic DNA Translation: EAE0436685.1
AABAJE010000002 Genomic DNA Translation: EAG1064445.1
AABARN010000003 Genomic DNA Translation: EAG1727722.1
AACKDQ010000002 Genomic DNA Translation: EAK9315684.1
AACKJR010000003 Genomic DNA Translation: EAK9807010.1
AAHZFN010000006 Genomic DNA Translation: ECB9473131.1
AAHZFV010000003 Genomic DNA Translation: ECB9500444.1
AAHZGA010000004 Genomic DNA Translation: ECB9518696.1
AALGDA010000001 Genomic DNA Translation: ECY9781387.1
BAZD01000010 Genomic DNA Translation: GAM95492.1

NCBI Reference Sequences

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RefSeqi
WP_010958956.1, NZ_WUDV01000004.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
lmok:CQ02_09465

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1639.1000.peg.2139

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAAGF010000003 Genomic DNA Translation: EAA0410767.1
AAAIVD010000003 Genomic DNA Translation: EAC5360770.1
AAAJKI010000001 Genomic DNA Translation: EAC6546782.1
AAAJSR010000004 Genomic DNA Translation: EAC7205032.1
AAAKRK010000005 Genomic DNA Translation: EAC9135143.1
AAAKTU010000002 Genomic DNA Translation: EAC9323174.1
AAAKVJ010000003 Genomic DNA Translation: EAC9449867.1
AAALCR010000002 Genomic DNA Translation: EAD0028589.1
AAAMQP010000004 Genomic DNA Translation: EAD3171154.1
AAANOM010000004 Genomic DNA Translation: EAD4984249.1
AAANYN010000002 Genomic DNA Translation: EAD5772953.1
AAAPCL010000003 Genomic DNA Translation: EAD8127817.1
AAAPKJ010000002 Genomic DNA Translation: EAD8746263.1
AAAQFV010000003 Genomic DNA Translation: EAE0436685.1
AABAJE010000002 Genomic DNA Translation: EAG1064445.1
AABARN010000003 Genomic DNA Translation: EAG1727722.1
AACKDQ010000002 Genomic DNA Translation: EAK9315684.1
AACKJR010000003 Genomic DNA Translation: EAK9807010.1
AAHZFN010000006 Genomic DNA Translation: ECB9473131.1
AAHZFV010000003 Genomic DNA Translation: ECB9500444.1
AAHZGA010000004 Genomic DNA Translation: ECB9518696.1
AALGDA010000001 Genomic DNA Translation: ECY9781387.1
BAZD01000010 Genomic DNA Translation: GAM95492.1
RefSeqiWP_010958956.1, NZ_WUDV01000004.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

KEGGilmok:CQ02_09465
PATRICifig|1639.1000.peg.2139

Phylogenomic databases

OrthoDBi2009156at2

Family and domain databases

CDDicd08646, FMT_core_Met-tRNA-FMT_N, 1 hit
cd08704, Met_tRNA_FMT_C, 1 hit
Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182, Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794, Fmt
IPR005793, Formyl_trans_C
IPR037022, Formyl_trans_C_sf
IPR002376, Formyl_transf_N
IPR036477, Formyl_transf_N_sf
IPR011034, Formyl_transferase-like_C_sf
IPR001555, GART_AS
IPR044135, Met-tRNA-FMT_C
IPR041711, Met-tRNA-FMT_N
PfamiView protein in Pfam
PF02911, Formyl_trans_C, 1 hit
PF00551, Formyl_trans_N, 1 hit
SUPFAMiSSF50486, SSF50486, 1 hit
SSF53328, SSF53328, 1 hit
TIGRFAMsiTIGR00460, fmt, 1 hit
PROSITEiView protein in PROSITE
PS00373, GART, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0B8R964_LISMN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0B8R964
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: April 7, 2021
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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