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Entry version 31 (12 Aug 2020)
Sequence version 1 (01 Apr 2015)
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Protein

Arginyl-tRNA synthetase

Gene

PARPA_01947.1 scaffold 1908

Organism
Parasitella parasitica
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminoacyl-tRNA synthetaseARBA annotation, DNA-bindingUniRule annotationARBA annotation, HelicaseARBA annotation, Hydrolase, Ligase
Biological processDNA replicationARBA annotation, Protein biosynthesisARBA annotation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Arginyl-tRNA synthetaseARBA annotation (EC:3.6.4.12ARBA annotation, EC:6.1.1.19ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PARPA_01947.1 scaffold 1908Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiParasitella parasiticaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri35722 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiFungi incertae sedisMucoromycotaMucoromycotinaMucoromycetesMucoralesMucorineaeMucoraceaeParasitella
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000054107 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini858 – 1064MCMInterPro annotationAdd BLAST207

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MCM family.UniRule annotation
Belongs to the class-I aminoacyl-tRNA synthetase family.ARBA annotation

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
266497at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1360.70, 1 hit
3.40.50.620, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001412, aa-tRNA-synth_I_CS
IPR001278, Arg-tRNA-ligase
IPR036695, Arg-tRNA-synth_N_sf
IPR035684, ArgRS_core
IPR008909, DALR_anticod-bd
IPR031327, MCM
IPR008048, MCM5
IPR018525, MCM_CS
IPR001208, MCM_dom
IPR041562, MCM_lid
IPR027925, MCM_N
IPR033762, MCM_OB
IPR012340, NA-bd_OB-fold
IPR027417, P-loop_NTPase
IPR014729, Rossmann-like_a/b/a_fold
IPR009080, tRNAsynth_Ia_anticodon-bd

The PANTHER Classification System

More...
PANTHERi
PTHR11630, PTHR11630, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05746, DALR_1, 1 hit
PF00493, MCM, 1 hit
PF17855, MCM_lid, 1 hit
PF14551, MCM_N, 1 hit
PF17207, MCM_OB, 1 hit
PF00750, tRNA-synt_1d, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01657, MCMFAMILY
PR01661, MCMPROTEIN5

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00836, DALR_1, 1 hit
SM00350, MCM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47323, SSF47323, 1 hit
SSF50249, SSF50249, 1 hit
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00456, argS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00178, AA_TRNA_LIGASE_I, 1 hit
PS00847, MCM_1, 1 hit
PS50051, MCM_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0B7MU10-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRPTKSRKDG HISISLPKLN TSLATPLTSQ QLSEWSRTIA SKFVPDEYIQ
60 70 80 90 100
QSSCKGSNLC FKFEETNFVK HVLQQVYREK DSYGWLHIPK PSNSTVLIDY
110 120 130 140 150
SSPNIAKPFH AGHLRSTIIG NFIKQIHKAL GYHIVGINYL GDWGKQYGFE
160 170 180 190 200
KYGNEAELVS DPIHHLYQVY VKINLDAKLD KDVDRKANEY FKRMEDGDPE
210 220 230 240 250
ALKQWKQFRD LSIKSYASMY QRLNVQFDVY SGESQVNTYI PKAYDQLKRS
260 270 280 290 300
HLLQRTEDGA LAIDLEKYHL GTAIVQRADG TSLYMTRDLA SILMRREKYP
310 320 330 340 350
FQKAIYVVGS EQAGYFKQLF QISNLVEYSN ENLQHVGFGR IKGMSTRNGT
360 370 380 390 400
AVFLQDILDT AKERIMDYMK QSEEKSQLEN IDAVADQLAM SAILIQDMKS
410 420 430 440 450
KRNKDYEFSW GRMTDARGDT GVFLQYAHAR ACGIERKAGI AIDPDCDFSI
460 470 480 490 500
LKEKEAINLV QCIAQFPETV EAAFATLEPS TIVNYLFKLS HATSTASACL
510 520 530 540 550
RVKDMDPDVS RARMLLFWSA RSTLKNGLHL LGIKPIEKIF GWDQGQVYST
560 570 580 590 600
SVLPGEERVN SISETTGLFF DFIQTFRLSN NYIYREQLSQ NLLTRQYYIE
610 620 630 640 650
VDVNHLISFN ADLANKLTTT PADYLPMFEN AVKDSAKRIL FANPKTVSNL
660 670 680 690 700
DVPDCQVTLK SSANVVQIRD LNSDYIGKLV RIPGIVIGAS TLSSRATQVT
710 720 730 740 750
AMCRSCRNTK VIPVTGGFSS IVLPRNCDSQ DLNGEGNNCP MDPFVIMHDK
760 770 780 790 800
CKFVDSQVIK LQEAPDMVPV GDLPRHTILN ADRWLTNRVV PGMRAIVMGI
810 820 830 840 850
YSIFQSKSAK STGAAAVRTP YIRIVGLQVD QHNNGRGKPH FTDAEEDEYI
860 870 880 890 900
RMSRQPDLYE TFARSLAPSI FGNMDIKKAI TCLLFSGSKK ILPDGMRLRG
910 920 930 940 950
DISVLLLGDP GTAKSQLLKF TEKVAPIAVY TSGKGSSAAG LTASVIRDPA
960 970 980 990 1000
SRDFYLEGGA MVLADGGVVC IDEFDKMRDE DRVAIHEAME QQTISIAKAG
1010 1020 1030 1040 1050
ITTILNSRTS VLAAANPVFG RYDDMKSAGE NIDFQTTILS RFDMIFIVKD
1060 1070 1080 1090 1100
DHNESRDMSI ARHVLNVHMN RQTQDAVMGE IDLEKMKAYI NYCKAKCAPR
1110 1120 1130 1140 1150
LTAAAATKLS SHFVTIRKEM KDTERDTEVR STIPITIRQL EAIIRISESL
1160 1170 1180 1190 1200
AKMTLSPYAN EQHVDEAIRL FKYSTLDAIS NGGADGMTRS DLMSEVQLIE
1210 1220 1230 1240 1250
KDIQKRLPVG SQVPCAKLKE HCLRDGYSEA AFSRALTILV RREMLVLRAQ

GKMVLRQGF
Length:1,259
Mass (Da):141,403
Last modified:April 1, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA7BF9E25E3F2449
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LN719792 Genomic DNA Translation: CEP08607.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN719792 Genomic DNA Translation: CEP08607.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Phylogenomic databases

OrthoDBi266497at2759

Family and domain databases

Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR001412, aa-tRNA-synth_I_CS
IPR001278, Arg-tRNA-ligase
IPR036695, Arg-tRNA-synth_N_sf
IPR035684, ArgRS_core
IPR008909, DALR_anticod-bd
IPR031327, MCM
IPR008048, MCM5
IPR018525, MCM_CS
IPR001208, MCM_dom
IPR041562, MCM_lid
IPR027925, MCM_N
IPR033762, MCM_OB
IPR012340, NA-bd_OB-fold
IPR027417, P-loop_NTPase
IPR014729, Rossmann-like_a/b/a_fold
IPR009080, tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11630, PTHR11630, 1 hit
PfamiView protein in Pfam
PF05746, DALR_1, 1 hit
PF00493, MCM, 1 hit
PF17855, MCM_lid, 1 hit
PF14551, MCM_N, 1 hit
PF17207, MCM_OB, 1 hit
PF00750, tRNA-synt_1d, 1 hit
PRINTSiPR01657, MCMFAMILY
PR01661, MCMPROTEIN5
SMARTiView protein in SMART
SM00836, DALR_1, 1 hit
SM00350, MCM, 1 hit
SUPFAMiSSF47323, SSF47323, 1 hit
SSF50249, SSF50249, 1 hit
SSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR00456, argS, 1 hit
PROSITEiView protein in PROSITE
PS00178, AA_TRNA_LIGASE_I, 1 hit
PS00847, MCM_1, 1 hit
PS50051, MCM_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0B7MU10_9FUNG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0B7MU10
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: August 12, 2020
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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