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Entry version 48 (11 Dec 2019)
Sequence version 1 (01 Apr 2015)
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Protein

3-dehydroquinate dehydratase

Gene

aroD

Organism
Streptococcus pneumoniae
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: chorismate biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate.UniRule annotation
Proteins known to be involved in the 7 steps of the subpathway in this organism are:
  1. Phospho-2-dehydro-3-deoxyheptonate aldolase (AZJ70_01390), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_2), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_1), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG1), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_1), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (A5N45_08075), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_2), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_3), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_1), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_2), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF_1), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroF), Phospho-2-dehydro-3-deoxyheptonate aldolase (aroG)
  2. 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB), 3-dehydroquinate synthase (aroB)
  3. 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD2), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD), 3-dehydroquinate dehydratase (aroD)
  4. Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE_1), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate 5-dehydrogenase (aroE_2), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE), Shikimate dehydrogenase (NADP(+)) (aroE)
  5. Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroK), Shikimate kinase (aroK), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroK), Shikimate kinase (aroL), Shikimate kinase (aroL), Shikimate kinase (aroK)
  6. 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA), 3-phosphoshikimate 1-carboxyvinyltransferase (aroA)
  7. Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroF_4), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC), Chorismate synthase (aroC)
This subpathway is part of the pathway chorismate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate, the pathway chorismate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei63-dehydroquinateUniRule annotation1
Binding sitei623-dehydroquinateUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei118Proton donor/acceptorUniRule annotation1
Active sitei143Schiff-base intermediate with substrateUniRule annotation1
Binding sitei1863-dehydroquinateUniRule annotation1
Binding sitei2053-dehydroquinateUniRule annotation1
Binding sitei2093-dehydroquinateUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyaseUniRule annotationImported
Biological processAmino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation
LigandSchiff baseUniRule annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00053;UER00086

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
3-dehydroquinate dehydrataseUniRule annotation (EC:4.2.1.10UniRule annotation)
Short name:
3-dehydroquinaseUniRule annotation
Alternative name(s):
Type I DHQaseUniRule annotation
Type I dehydroquinaseUniRule annotation
Short name:
DHQ1UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:aroDUniRule annotationImported
ORF Names:A4260_03550Imported, A5N45_05010Imported, CWI64_02360Imported, ERS003549_00638Imported, ERS020408_00429Imported, ERS043879_01050Imported, ERS232497_00083Imported, NCTC12140_01041Imported, SAMEA104035134_00457Imported, SAMEA104035170_00997Imported, SAMEA104035600_00746Imported, SAMEA104035685_00357Imported, SAMEA104154639_00966Imported, SAMEA104154682_00398Imported, SAMEA2066278_01934Imported, SAMEA2335968_01940Imported, SAMEA2696480_02114Imported, SAMEA2796717_00290Imported, SAMEA2796719_00465Imported, SAMEA2797380_00350Imported, SAMEA3207204_00436Imported, SAMEA3232645_00405Imported, SAMEA3354337_00900Imported, SAMEA3389847_00238Imported, SAMEA3714180_00300Imported, SAMEA3714202_00640Imported, SAMEA4038883_01384Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptococcus pneumoniaeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1313 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000313602 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000314072 Componenti: Unassembled WGS sequence
  • UP000093517 Componenti: Unassembled WGS sequence
  • UP000312674 Componenti: Unassembled WGS sequence
  • UP000314170 Componenti: Unassembled WGS sequence
  • UP000255473 Componenti: Unassembled WGS sequence
  • UP000312104 Componenti: Unassembled WGS sequence
  • UP000214939 Componenti: Unassembled WGS sequence
  • UP000313333 Componenti: Unassembled WGS sequence
  • UP000073844 Componenti: Unassembled WGS sequence
  • UP000313172 Componenti: Unassembled WGS sequence
  • UP000071938 Componenti: Unassembled WGS sequence
  • UP000075030 Componenti: Unassembled WGS sequence
  • UP000310500 Componenti: Unassembled WGS sequence
  • UP000046154 Componenti: Unassembled WGS sequence
  • UP000312470 Componenti: Unassembled WGS sequence
  • UP000072289 Componenti: Unassembled WGS sequence
  • UP000311586 Componenti: Unassembled WGS sequence
  • UP000298921 Componenti: Unassembled WGS sequence
  • UP000044473 Componenti: Unassembled WGS sequence
  • UP000310307 Componenti: Unassembled WGS sequence
  • UP000310997 Componenti: Unassembled WGS sequence
  • UP000311821 Componenti: Unassembled WGS sequence
  • UP000232067 Componenti: Chromosome
  • UP000314803 Componenti: Unassembled WGS sequence
  • UP000042569 Componenti: Unassembled WGS sequence
  • UP000311673 Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni30 – 323-dehydroquinate bindingUniRule annotation3

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the type-I 3-dehydroquinase family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105FF2 Bacteria
COG0710 LUCA

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00502 DHQase_I, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.70, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00214 AroD, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013785 Aldolase_TIM
IPR001381 DHquinase_I

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01487 DHquinase_I, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01093 aroD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0B7LT97-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLIVSVMPR SLEEAQALDA TRYLDADIIE WRADYLPKEA ILQVAPAIFE
60 70 80 90 100
KFAGRELVFT LRTRSEGGEI DLSPEEYIHL IKEVAQLYQP DYIDFEYYSY
110 120 130 140 150
KDVFEEMLDF PNLVLSYHNF QETPENMMEI LSELTILNPK LVKVAVMAHT
160 170 180 190 200
EQDVLDLMNY TRGFKTLNPE QEYVTISMGK VGKVSRITAD VTGSSWSFAS
210 220
LDEVSAPGQI SLASMKKIRE ILDEA
Length:225
Mass (Da):25,719
Last modified:April 1, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1829E189C5BAEFB9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP025076 Genomic DNA Translation: AUB32585.1
CKOR01000003 Genomic DNA Translation: CIX16494.1
CMPS01000002 Genomic DNA Translation: CKE28338.1
CNOG02000134 Genomic DNA Translation: CTO26258.1
FIYJ01000003 Genomic DNA Translation: CZD78107.1
LWGW01000017 Genomic DNA Translation: OCQ84867.1
NNBW01000059 Genomic DNA Translation: OYL29258.1
UHGR01000001 Genomic DNA Translation: SUO26184.1
CAALQR010000004 Genomic DNA Translation: VJF64277.1
FHJQ02000009 Genomic DNA Translation: VJN00746.1
CAANCU010000017 Genomic DNA Translation: VKC23756.1
FHVI02000002 Genomic DNA Translation: VND07311.1
FHVH02000004 Genomic DNA Translation: VND65671.1
CAAUND010000018 Genomic DNA Translation: VOI02761.1
CAAVWW010000001 Genomic DNA Translation: VPB04519.1
CAAVYO010000005 Genomic DNA Translation: VPB97267.1
CAAWCY010000003 Genomic DNA Translation: VPE40818.1
CAAWPC010000003 Genomic DNA Translation: VPK98568.1
CAAXHV010000001 Genomic DNA Translation: VPV11417.1
CAAXUT010000003 Genomic DNA Translation: VQC19925.1
CAAZBH010000002 Genomic DNA Translation: VQT79168.1
CABBQX010000003 Genomic DNA Translation: VSE70747.1
CABBZR010000004 Genomic DNA Translation: VSJ51987.1
CABCGX010000004 Genomic DNA Translation: VSN46211.1
CABCYJ010000002 Genomic DNA Translation: VSW90828.1
CABDDM010000003 Genomic DNA Translation: VTA02840.1
CABDLL010000009 Genomic DNA Translation: VTE39486.1

NCBI Reference Sequences

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RefSeqi
WP_000767762.1, NZ_VFBK01000018.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

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EnsemblBacteriai
CIT55607; CIT55607; ERS019595_00010
CIV43515; CIV43515; ERS019687_00096
CIX01651; CIX01651; ERS019416_00548
CIX16494; CIX16494; ERS020408_00429
CJC52765; CJC52765; ERS021447_05061
CJE92522; CJE92522; ERS020831_00267
CJF29411; CJF29411; ERS021300_00382
CJM12270; CJM12270; ERS022045_04928
CJO05807; CJO05807; ERS022232_05072
CJS29124; CJS29124; ERS021733_03247
CKA07455; CKA07455; ERS022522_00153
CKE28338; CKE28338; ERS232497_00083
CKF99273; CKF99273; ERS232524_02270
CNZ05131; CNZ05131; ERS020873_00902
CNZ58760; CNZ58760; ERS020881_00318
COD49624; COD49624; ERS020178_03612
COG29535; COG29535; ERS020726_00149
CTO26258; CTO26258; ERS043879_01050
CVM74924; CVM74924; ERS367628_01269
CVQ56295; CVQ56295; ERS515225_01495
CVU63304; CVU63304; ERS409165_00140
CVY94136; CVY94136; ERS409372_01348
CWM14656; CWM14656; ERS515182_01109
CYL56131; CYL56131; ERS455085_00125
CYO49238; CYO49238; ERS558328_00290
CZD78107; CZD78107; ERS003549_00638
OCQ84867; OCQ84867; A4260_03550

Pathosystems Resource Integration Center (PATRIC)

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PATRICi
fig|1313.13073.peg.1461

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP025076 Genomic DNA Translation: AUB32585.1
CKOR01000003 Genomic DNA Translation: CIX16494.1
CMPS01000002 Genomic DNA Translation: CKE28338.1
CNOG02000134 Genomic DNA Translation: CTO26258.1
FIYJ01000003 Genomic DNA Translation: CZD78107.1
LWGW01000017 Genomic DNA Translation: OCQ84867.1
NNBW01000059 Genomic DNA Translation: OYL29258.1
UHGR01000001 Genomic DNA Translation: SUO26184.1
CAALQR010000004 Genomic DNA Translation: VJF64277.1
FHJQ02000009 Genomic DNA Translation: VJN00746.1
CAANCU010000017 Genomic DNA Translation: VKC23756.1
FHVI02000002 Genomic DNA Translation: VND07311.1
FHVH02000004 Genomic DNA Translation: VND65671.1
CAAUND010000018 Genomic DNA Translation: VOI02761.1
CAAVWW010000001 Genomic DNA Translation: VPB04519.1
CAAVYO010000005 Genomic DNA Translation: VPB97267.1
CAAWCY010000003 Genomic DNA Translation: VPE40818.1
CAAWPC010000003 Genomic DNA Translation: VPK98568.1
CAAXHV010000001 Genomic DNA Translation: VPV11417.1
CAAXUT010000003 Genomic DNA Translation: VQC19925.1
CAAZBH010000002 Genomic DNA Translation: VQT79168.1
CABBQX010000003 Genomic DNA Translation: VSE70747.1
CABBZR010000004 Genomic DNA Translation: VSJ51987.1
CABCGX010000004 Genomic DNA Translation: VSN46211.1
CABCYJ010000002 Genomic DNA Translation: VSW90828.1
CABDDM010000003 Genomic DNA Translation: VTA02840.1
CABDLL010000009 Genomic DNA Translation: VTE39486.1
RefSeqiWP_000767762.1, NZ_VFBK01000018.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCIT55607; CIT55607; ERS019595_00010
CIV43515; CIV43515; ERS019687_00096
CIX01651; CIX01651; ERS019416_00548
CIX16494; CIX16494; ERS020408_00429
CJC52765; CJC52765; ERS021447_05061
CJE92522; CJE92522; ERS020831_00267
CJF29411; CJF29411; ERS021300_00382
CJM12270; CJM12270; ERS022045_04928
CJO05807; CJO05807; ERS022232_05072
CJS29124; CJS29124; ERS021733_03247
CKA07455; CKA07455; ERS022522_00153
CKE28338; CKE28338; ERS232497_00083
CKF99273; CKF99273; ERS232524_02270
CNZ05131; CNZ05131; ERS020873_00902
CNZ58760; CNZ58760; ERS020881_00318
COD49624; COD49624; ERS020178_03612
COG29535; COG29535; ERS020726_00149
CTO26258; CTO26258; ERS043879_01050
CVM74924; CVM74924; ERS367628_01269
CVQ56295; CVQ56295; ERS515225_01495
CVU63304; CVU63304; ERS409165_00140
CVY94136; CVY94136; ERS409372_01348
CWM14656; CWM14656; ERS515182_01109
CYL56131; CYL56131; ERS455085_00125
CYO49238; CYO49238; ERS558328_00290
CZD78107; CZD78107; ERS003549_00638
OCQ84867; OCQ84867; A4260_03550
PATRICifig|1313.13073.peg.1461

Phylogenomic databases

eggNOGiENOG4105FF2 Bacteria
COG0710 LUCA

Enzyme and pathway databases

UniPathwayiUPA00053;UER00086

Family and domain databases

CDDicd00502 DHQase_I, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00214 AroD, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001381 DHquinase_I
PfamiView protein in Pfam
PF01487 DHquinase_I, 1 hit
TIGRFAMsiTIGR01093 aroD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0B7LT97_STREE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0B7LT97
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: December 11, 2019
This is version 48 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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