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Protein

Transcription termination/antitermination protein NusG

Gene

nusG

Organism
Yersinia intermedia
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.UniRule annotation

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription antiterminationUniRule annotationSAAS annotation, Transcription regulation, Transcription terminationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination/antitermination protein NusGUniRule annotationSAAS annotation
Gene namesi
Name:nusGUniRule annotationImported
Synonyms:nusG_2Imported
ORF Names:CBW57_20965Imported, ERS008449_04143Imported, ERS008476_04205Imported, ERS008530_04739Imported, ERS008547_04129Imported
OrganismiYersinia intermediaImported
Taxonomic identifieri631 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000043316 Componenti: Unassembled WGS sequence
  • UP000042195 Componenti: Unassembled WGS sequence
  • UP000196440 Componenti: Unassembled WGS sequence
  • UP000045423 Componenti: Unassembled WGS sequence
  • UP000038750 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 115NGNInterPro annotationAdd BLAST110
Domaini127 – 154KOWInterPro annotationAdd BLAST28

Sequence similaritiesi

Belongs to the NusG family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK02601

Family and domain databases

Gene3Di2.30.30.30, 1 hit
3.30.70.940, 1 hit
HAMAPiMF_00948 NusG, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR006645 NGN_dom
IPR036735 NGN_dom_sf
IPR014722 Rib_L2_dom2
IPR001062 Transcrpt_antiterm_NusG
IPR015869 Transcrpt_antiterm_NusG_bac_CS
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30265:SF2 PTHR30265:SF2, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF02357 NusG, 1 hit
PRINTSiPR00338 NUSGTNSCPFCT
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SM00738 NGN, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF82679 SSF82679, 1 hit
TIGRFAMsiTIGR00922 nusG, 1 hit
PROSITEiView protein in PROSITE
PS01014 NUSG, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0B6I9A9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEAPKKRWY VVQAFSGFEG RVAQSLREHI KLHDMEELFG EVMVPTEEVV
60 70 80 90 100
EIRGGQRRKS ERKFFPGYVL VQMVMNDASW HLVRSVPRVM GFIGGTSDRP
110 120 130 140 150
APISDKEVDA IMNRLQQVGD KPRPKTLFEP GELVRVSDGP FADFNGVVEE
160 170 180
VDYEKSRLKV SVSIFGRATP VELDFSQVEK G
Length:181
Mass (Da):20,514
Last modified:April 1, 2015 - v1
Checksum:iC078FF359DFE1826
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CPZJ01000040 Genomic DNA Translation: CNG79487.1
CQER01000022 Genomic DNA Translation: CNL99368.1
CTFA01000081 Genomic DNA Translation: CQD59200.1
CWJI01000024 Genomic DNA Translation: CRY57154.1
NHOI01000038 Genomic DNA Translation: OVZ82132.1
RefSeqiWP_002210671.1, NZ_NHOI01000038.1

Genome annotation databases

EnsemblBacteriaiCNG79487; CNG79487; ERS008530_04739
CNL99368; CNL99368; ERS008547_04129
CQD59200; CQD59200; ERS008449_04143
CRY57154; CRY57154; ERS008476_04205
GeneIDi31914128
KEGGiyin:CH53_2090

Similar proteinsi

Entry informationi

Entry nameiA0A0B6I9A9_YERIN
AccessioniPrimary (citable) accession number: A0A0B6I9A9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: July 18, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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