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Protein
Submitted name:

La-related protein 1

Gene

LARP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
La-related protein 1Imported
Gene namesi
Name:LARP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000155506.16
HGNCiHGNC:29531 LARP1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155506

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0B4J210

Expressioni

Gene expression databases

BgeeiENSG00000155506 Expressed in 251 organ(s), highest expression level in female gonad
ExpressionAtlasiA0A0B4J210 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0B4J210
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini397 – 487HTH La-type RNA-bindingInterPro annotationAdd BLAST91

Phylogenomic databases

eggNOGiKOG2590 Eukaryota
COG5193 LUCA
GeneTreeiENSGT00390000000523

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR006630 La_HTH
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF05383 La, 1 hit
SMARTiView protein in SMART
SM00715 LA, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50961 HTH_LA, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

A0A0B4J210-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATQVEPLLP GGATLLQAEE HGGLVRKKPP PAPEGKGEPG PNDVRGGEPD
60 70 80 90 100
GSARRPRPPC AKPHKEGTGQ QERESPRPLQ LPGAEGPAIS DGEEGGGEPG
110 120 130 140 150
AGGGAAGAAG AGRRDFVEAP PPKVNPWTKN ALPPVLTTVN GQSPPEHSAP
160 170 180 190 200
AKVVRAAVPK QRKGSKVGDF GDAINWPTPG EIAHKSVQPQ SHKPQPTRKL
210 220 230 240 250
PPKKDMKEQE KGEGSDSKES PKTKSDESGE EKNGDEDCQR GGQKKKGNKH
260 270 280 290 300
KWVPLQIDMK PEVPREKLAS RPTRPPEPRH IPANRGEIKG SESATYVPVA
310 320 330 340 350
PPTPAWQPEI KPEPAWHDQD ETSSVKSDGA GGARASFRGR GRGRGRGRGR
360 370 380 390 400
GRGGTRTHFD YQFGYRKFDG VEGPRTPKYM NNITYYFDNV SSTELYSVDQ
410 420 430 440 450
ELLKDYIKRQ IEYYFSVDNL ERDFFLRRKM DADGFLPITL IASFHRVQAL
460 470 480 490 500
TTDISLIFAA LKDSKVVEIV DEKVRRREEP EKWPLPPIVD YSQTDFSQLL
510 520 530 540 550
NCPEFVPRQH YQKETESAPG SPRAVTPVPT KTEEVSNLKT LPKGLSASLP
560 570 580 590 600
DLDSENWIEV KKRPRPSPAR PKKSEESRFS HLTSLPQQLP SQQLMSKDQD
610 620 630 640 650
EQEELDFLFD EEMEQMDGRK NTFTAWSDEE SDYEIDDRDV NKILIVTQTP
660 670 680 690 700
HYMRRHPGGD RTGNHTSRAK MSAELAKVIN DGLFYYEQDL WAEKFEPEYS
710 720 730 740 750
QIKQEVENFK KVNMISREQF DTLTPEPPVD PNQEVPPGPP RFQQVPTDAL
760 770 780 790 800
ANKLFGAPEP STIARSLPTT VPESPNYRNT RTPRTPRTPQ LKDSSQTSRF
810
YPVVKEGRTL DAKMP
Length:815
Mass (Da):90,822
Last modified:October 5, 2016 - v5
Checksum:i94CAEBEF4067F6FE
GO

Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6PKG0LARP1_HUMAN
La-related protein 1
LARP1 KIAA0731, LARP
1,096Annotation score:
H0YC73H0YC73_HUMAN
La-related protein 1
LARP1
195Annotation score:
H0YBW1H0YBW1_HUMAN
La-related protein 1
LARP1
281Annotation score:
E5RH50E5RH50_HUMAN
La-related protein 1
LARP1
610Annotation score:
H0YAN4H0YAN4_HUMAN
La-related protein 1
LARP1
150Annotation score:
H0YC33H0YC33_HUMAN
La-related protein 1
LARP1
183Annotation score:
H0YAX9H0YAX9_HUMAN
La-related protein 1
LARP1
61Annotation score:
H0YBR8H0YBR8_HUMAN
La-related protein 1
LARP1
36Annotation score:
E5RHK4E5RHK4_HUMAN
La-related protein 1
LARP1
92Annotation score:
H0YBM7H0YBM7_HUMAN
La-related protein 1
LARP1
167Annotation score:
There is more potential isoformShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei815Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008379 Genomic DNA No translation available.
AC112169 Genomic DNA No translation available.
KC877140 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000518297; ENSP00000428589; ENSG00000155506

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008379 Genomic DNA No translation available.
AC112169 Genomic DNA No translation available.
KC877140 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A0B4J210
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A0B4J210

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000518297; ENSP00000428589; ENSG00000155506

Organism-specific databases

EuPathDBiHostDB:ENSG00000155506.16
HGNCiHGNC:29531 LARP1
OpenTargetsiENSG00000155506
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2590 Eukaryota
COG5193 LUCA
GeneTreeiENSGT00390000000523

Miscellaneous databases

ChiTaRSiLARP1 human

Gene expression databases

BgeeiENSG00000155506 Expressed in 251 organ(s), highest expression level in female gonad
ExpressionAtlasiA0A0B4J210 baseline and differential

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR006630 La_HTH
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF05383 La, 1 hit
SMARTiView protein in SMART
SM00715 LA, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50961 HTH_LA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0B4J210_HUMAN
AccessioniPrimary (citable) accession number: A0A0B4J210
Entry historyiIntegrated into UniProtKB/TrEMBL: March 4, 2015
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 36 of the entry and version 5 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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