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Protein

Thymidine kinase

Gene

tdk

Organism
Porphyromonas gulae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei96Proton acceptorUniRule annotation1
Metal bindingi152ZincUniRule annotation1
Metal bindingi155ZincUniRule annotation1
Metal bindingi184ZincUniRule annotation1
Metal bindingi187ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 30ATPUniRule annotation8
Nucleotide bindingi95 – 98ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
ORF Names:HR08_07770Imported, HR15_07085Imported
OrganismiPorphyromonas gulaeImported
Taxonomic identifieri111105 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
Proteomesi
  • UP000030130 Componenti: Unassembled WGS sequence
  • UP000030146 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0A2F969-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDYEIENNHA DNIRRGSIEV ICGSMFSGKT EELLRRLRRA KIARQTVEIF
60 70 80 90 100
KPTIDMRYDE TDVVSHDRNA IASTPVDNSA NILLLSSQVD VVGIDEAQFF
110 120 130 140 150
DEGLVEVAQR LADQGVRVVI AGLDMDFRRQ PFGPMPGLCA IADSVTKVHA
160 170 180 190 200
VCVECGRLAS YSFRRVQGDQ QVMLGELNEY SPLCRTCYRK CSSLPQTEEI

HSTI
Length:204
Mass (Da):22,858
Last modified:February 4, 2015 - v1
Checksum:i0CD048630CA35331
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JRAI01000063 Genomic DNA Translation: KGN84944.1
JRAK01000091 Genomic DNA Translation: KGN87136.1
RefSeqiWP_018964584.1, NZ_KQ040410.1

Genome annotation databases

EnsemblBacteriaiKGN84944; KGN84944; HR08_07770
KGN87136; KGN87136; HR15_07085
PATRICifig|111105.18.peg.141

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JRAI01000063 Genomic DNA Translation: KGN84944.1
JRAK01000091 Genomic DNA Translation: KGN87136.1
RefSeqiWP_018964584.1, NZ_KQ040410.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiKGN84944; KGN84944; HR08_07770
KGN87136; KGN87136; HR15_07085
PATRICifig|111105.18.peg.141

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0A2F969_9PORP
AccessioniPrimary (citable) accession number: A0A0A2F969
Entry historyiIntegrated into UniProtKB/TrEMBL: February 4, 2015
Last sequence update: February 4, 2015
Last modified: March 28, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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