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Entry version 23 (11 Dec 2019)
Sequence version 1 (04 Feb 2015)
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Protein

Ferrous iron transport protein B

Gene

HQ37_00205

Organism
Porphyromonas sp. COT-239 OH1446
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transporter of a GTP-driven Fe2+ uptake system.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Iron transportUniRule annotation, Transport
LigandGTP-bindingUniRule annotation, Iron, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ferrous iron transport protein BUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:HQ37_00205Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPorphyromonas sp. COT-239 OH1446Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1515613 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonasunclassified Porphyromonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000030150 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei423 – 443HelicalUniRule annotationAdd BLAST21
Transmembranei474 – 503HelicalUniRule annotationAdd BLAST30
Transmembranei557 – 583HelicalUniRule annotationAdd BLAST27
Transmembranei589 – 609HelicalUniRule annotationAdd BLAST21
Transmembranei647 – 668HelicalUniRule annotationAdd BLAST22
Transmembranei792 – 815HelicalUniRule annotationAdd BLAST24
Transmembranei827 – 850HelicalUniRule annotationAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
1515613.HQ37_00205

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini119 – 282FeoB-type GInterPro annotationAdd BLAST164

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili668 – 688Sequence analysisAdd BLAST21

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
304844at2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01879 FeoB, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.90, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007167 Fe-transptr_FeoA
IPR003373 Fe2_transport_prot-B
IPR011640 Fe2_transport_prot_B_C
IPR038157 FeoA_core_dom
IPR041069 FeoB_Cyto
IPR030389 G_FEOB_dom
IPR011642 Gate_dom
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
IPR008988 Transcriptional_repressor_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04023 FeoA, 1 hit
PF07664 FeoB_C, 1 hit
PF17910 FeoB_Cyto, 1 hit
PF02421 FeoB_N, 1 hit
PF07670 Gate, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00326 GTP1OBG

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00899 FeoA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50037 SSF50037, 1 hit
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00437 feoB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51711 G_FEOB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0A2DZI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLSELKAGQ KAVIQRVDGT GQFRKRILEM GFVQGKEVTV VQGAPLKDPI
60 70 80 90 100
YYRILDYNVS LRLEDGAKIE VRLLPEEGLQ AASADTSEES ILQPREPEQE
110 120 130 140 150
LGNMLPLRSR QHGKGNNKHL RIALVGNPNC GKTSLFNQAS GAHEHVGNYS
160 170 180 190 200
GVTIEAKTGY IYYRDYRIEI IDLPGAYSLS AYSPEELYIR DFLLGEKRPD
210 220 230 240 250
LVLNVLDTCN LERNLYLTLQ VKELGLPIVA ALNMFDEFAT RGERLNYPKL
260 270 280 290 300
ARLLGVPMIP TVCRTGLGLQ ALFDEIIEVW EGMLEGREEV ISPEIGKIRP
310 320 330 340 350
IQVNYGSLLE PVIEELSTKI DQHLPFEADR PPTRYIASRL VEGDKPLEDQ
360 370 380 390 400
LMNRYPKAAF IISARDYALR TIKDELTSHD AEELMTDARY GFISGALRET
410 420 430 440 450
YQANRQHRES LTDKIDHIVA HRLWGFPIFL LLMYVMFQAT FSLGQYPMDW
460 470 480 490 500
IEAGVGMLGD FIASSMQEGP LRDLLVDGII AGVGGVIVFL PNILILYFFI
510 520 530 540 550
SIFEDTGYMA RSAFIMDKIM HRMGLHGKSF IPLIMGFGCN VPAIMSTRTI
560 570 580 590 600
ESRKSRMITM LVVPFMSCSA RLPVYLLLAG ALFPDRAALV LFVLYLSGIL
610 620 630 640 650
IAVLSARLLK STYFKGEDVP FVMELPPYRL PTAQSVVRHM WARAKQYLHK
660 670 680 690 700
MGTVILVASI VIWFLGYFPR QSEQEQQLAD QIERLEQNPN LNEEERNSQR
710 720 730 740 750
IELEHAFAQY HQENSWIGRI GHASEPLIRP LGFDWKMGVS LISGLAAKEV
760 770 780 790 800
VVSTLGVIYT GDPDDSEEAQ HQLSERIRQE KRPDGSPSFT PLVAMGFMLF
810 820 830 840 850
VLIYFPCVAT IIAIARESGS WRWGAFSVIY SCALAWFVAF AVHQIGHLLV

V
Length:851
Mass (Da):95,949
Last modified:February 4, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i53F2AC9E5F93BF03
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
JRAO01000003 Genomic DNA Translation: KGN72083.1

NCBI Reference Sequences

More...
RefSeqi
WP_036878619.1, NZ_JRAO01000003.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
KGN72083; KGN72083; HQ37_00205

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JRAO01000003 Genomic DNA Translation: KGN72083.1
RefSeqiWP_036878619.1, NZ_JRAO01000003.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi1515613.HQ37_00205

Genome annotation databases

EnsemblBacteriaiKGN72083; KGN72083; HQ37_00205

Phylogenomic databases

OrthoDBi304844at2

Family and domain databases

CDDicd01879 FeoB, 1 hit
Gene3Di2.30.30.90, 1 hit
InterProiView protein in InterPro
IPR007167 Fe-transptr_FeoA
IPR003373 Fe2_transport_prot-B
IPR011640 Fe2_transport_prot_B_C
IPR038157 FeoA_core_dom
IPR041069 FeoB_Cyto
IPR030389 G_FEOB_dom
IPR011642 Gate_dom
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
IPR008988 Transcriptional_repressor_C
PfamiView protein in Pfam
PF04023 FeoA, 1 hit
PF07664 FeoB_C, 1 hit
PF17910 FeoB_Cyto, 1 hit
PF02421 FeoB_N, 1 hit
PF07670 Gate, 2 hits
PRINTSiPR00326 GTP1OBG
SMARTiView protein in SMART
SM00899 FeoA, 1 hit
SUPFAMiSSF50037 SSF50037, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00437 feoB, 1 hit
PROSITEiView protein in PROSITE
PS51711 G_FEOB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0A2DZI7_9PORP
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0A2DZI7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 4, 2015
Last sequence update: February 4, 2015
Last modified: December 11, 2019
This is version 23 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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