Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptide deformylase

Gene

def

Organism
Prochlorococcus sp. MIT 0601
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide.UniRule annotationSAAS annotation

Cofactori

Fe2+UniRule annotationNote: Binds 1 Fe2+ ion.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi121IronUniRule annotation1
Metal bindingi163IronUniRule annotation1
Active sitei164UniRule annotation1
Metal bindingi167IronUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processProtein biosynthesisUniRule annotationSAAS annotation
LigandIronUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide deformylaseUniRule annotationSAAS annotation (EC:3.5.1.88UniRule annotationSAAS annotation)
Short name:
PDFUniRule annotation
Alternative name(s):
Polypeptide deformylaseUniRule annotation
Gene namesi
Name:defUniRule annotation
ORF Names:EV05_0994Imported
OrganismiProchlorococcus sp. MIT 0601Imported
Taxonomic identifieri1499498 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000030414 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the polypeptide deformylase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00487 Pep_deformylase, 1 hit
Gene3Di3.90.45.10, 1 hit
HAMAPiMF_00163 Pep_deformylase, 1 hit
InterProiView protein in InterPro
IPR023635 Peptide_deformylase
IPR036821 Peptide_deformylase_sf
PANTHERiPTHR10458 PTHR10458, 1 hit
PfamiView protein in Pfam
PF01327 Pep_deformylase, 1 hit
PIRSFiPIRSF004749 Pep_def, 1 hit
PRINTSiPR01576 PDEFORMYLASE
SUPFAMiSSF56420 SSF56420, 1 hit
TIGRFAMsiTIGR00079 pept_deformyl, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0A2BLB1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARNFAQLAK NAEKGGSNIL VSKEPTEKPS LEIHTLGNLG LRQSAKRISK
60 70 80 90 100
VDDSIRTIIK KMLHSMYSAK GIGLAAPQVG IHQQLLVIDL DIENSTTPPI
110 120 130 140 150
ILINPEITEF SASIETYEEG CLSIPGVYLN VIRPSSIKLN YRDEMGRPKK
160 170 180 190 200
LSADGLLSRC IQHEMDHLNG VLFVDRVTNQ EDLNKELTEH GFQQKDVMSI

P
Length:201
Mass (Da):22,330
Last modified:February 4, 2015 - v1
Checksum:i4FC1D00DA7BBAE3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JNAU01000004 Genomic DNA Translation: KGG13314.1
RefSeqiWP_036901774.1, NZ_JNAU01000004.1

Genome annotation databases

EnsemblBacteriaiKGG13314; KGG13314; EV05_0994

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JNAU01000004 Genomic DNA Translation: KGG13314.1
RefSeqiWP_036901774.1, NZ_JNAU01000004.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiKGG13314; KGG13314; EV05_0994

Family and domain databases

CDDicd00487 Pep_deformylase, 1 hit
Gene3Di3.90.45.10, 1 hit
HAMAPiMF_00163 Pep_deformylase, 1 hit
InterProiView protein in InterPro
IPR023635 Peptide_deformylase
IPR036821 Peptide_deformylase_sf
PANTHERiPTHR10458 PTHR10458, 1 hit
PfamiView protein in Pfam
PF01327 Pep_deformylase, 1 hit
PIRSFiPIRSF004749 Pep_def, 1 hit
PRINTSiPR01576 PDEFORMYLASE
SUPFAMiSSF56420 SSF56420, 1 hit
TIGRFAMsiTIGR00079 pept_deformyl, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0A2BLB1_9PROC
AccessioniPrimary (citable) accession number: A0A0A2BLB1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 4, 2015
Last sequence update: February 4, 2015
Last modified: June 20, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again