UniProtKB - A0A0A0MTR0 (A0A0A0MTR0_HUMAN)
Protein
Submitted name:
Transient receptor potential cation channel subfamily M member 1
Gene
TRPM1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cation channel activity Source: InterPro
GO - Biological processi
- cellular response to light stimulus Source: InterPro
- G protein-coupled glutamate receptor signaling pathway Source: InterPro
Keywordsi
Biological process | Ion transportARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: Transient receptor potential cation channel subfamily M member 1Imported |
Gene namesi | Name:TRPM1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7146, TRPM1 |
VEuPathDBi | HostDB:ENSG00000134160.13 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000134160, Expressed in pigmented layer of retina and 87 other tissues |
ExpressionAtlasi | A0A0A0MTR0, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 228 | LSDAT_eukInterPro annotationAdd BLAST | 228 |
Keywords - Domaini
Transmembrane, Transmembrane helixARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155024 |
HOGENOMi | CLU_046430_0_1_1 |
Family and domain databases
InterProi | View protein in InterPro IPR029588, TRPM1 IPR041491, TRPM_SLOG |
PANTHERi | PTHR13800:SF13, PTHR13800:SF13, 1 hit |
Pfami | View protein in Pfam PF18139, LSDAT_euk, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
A0A0A0MTR0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
YIRVSYDTKP DSLLHLMVKD WQLELPKLLI SVHGGLQNFE MQPKLKQVFG
60 70 80 90 100
KGLIKAAMTT GAWIFTGGVS TGVISHVGDA LKDHSSKSRG RVCAIGIAPW
110 120 130 140 150
GIVENKEDLV GKDVTRVYQT MSNPLSKLSV LNNSHTHFIL ADNGTLGKYG
160 170 180 190 200
AEVKLRRLLE KHISLQKINT RLGQGVPLVG LVVEGGPNVV SIVLEYLQEE
210 220
PPIPVVICDG SGRASDILSF AHKYCEEGG
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ7Z4N2 | TRPM1_HUMAN | Transient receptor potential cation... | TRPM1 LTRPC1, MLSN, MLSN1 | 1,603 | Annotation score: | ||
H0YM61 | H0YM61_HUMAN | Transient receptor potential cation... | TRPM1 | 505 | Annotation score: | ||
H0YKU7 | H0YKU7_HUMAN | Transient receptor potential cation... | TRPM1 | 1,390 | Annotation score: | ||
A0A0A0MTQ9 | A0A0A0MTQ9_HUMAN | Transient receptor potential cation... | TRPM1 | 1,526 | Annotation score: | ||
A0A0G2JMJ5 | A0A0G2JMJ5_HUMAN | Transient receptor potential cation... | TRPM1 | 1,603 | Annotation score: | ||
A0A0G2JMR4 | A0A0G2JMR4_HUMAN | Transient receptor potential cation... | TRPM1 | 1,625 | Annotation score: | ||
A0A0G2JN34 | A0A0G2JN34_HUMAN | Transient receptor potential cation... | TRPM1 | 1,642 | Annotation score: | ||
A0A0G2JPN6 | A0A0G2JPN6_HUMAN | Transient receptor potential cation... | TRPM1 | 1,603 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009562 Genomic DNA No translation available. AC090829 Genomic DNA No translation available. AC243586 Genomic DNA No translation available. AC243758 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000560801; ENSP00000453644; ENSG00000134160 ENST00000621076; ENSP00000483610; ENSG00000274965 |
UCSCi | uc059hco.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009562 Genomic DNA No translation available. AC090829 Genomic DNA No translation available. AC243586 Genomic DNA No translation available. AC243758 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENST00000560801; ENSP00000453644; ENSG00000134160 ENST00000621076; ENSP00000483610; ENSG00000274965 |
UCSCi | uc059hco.1, human |
Organism-specific databases
HGNCi | HGNC:7146, TRPM1 |
OpenTargetsi | ENSG00000134160 |
VEuPathDBi | HostDB:ENSG00000134160.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155024 |
HOGENOMi | CLU_046430_0_1_1 |
Miscellaneous databases
ChiTaRSi | TRPM1, human |
Gene expression databases
Bgeei | ENSG00000134160, Expressed in pigmented layer of retina and 87 other tissues |
ExpressionAtlasi | A0A0A0MTR0, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR029588, TRPM1 IPR041491, TRPM_SLOG |
PANTHERi | PTHR13800:SF13, PTHR13800:SF13, 1 hit |
Pfami | View protein in Pfam PF18139, LSDAT_euk, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0A0MTR0_HUMAN | |
Accessioni | A0A0A0MTR0Primary (citable) accession number: A0A0A0MTR0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 7, 2015 |
Last sequence update: | January 7, 2015 | |
Last modified: | February 10, 2021 | |
This is version 40 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |