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Entry version 59 (02 Jun 2021)
Sequence version 1 (07 Jan 2015)
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Protein
Submitted name:

Laminin subunit alpha-4

Gene

LAMA4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

ARBA annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Laminin subunit alpha-4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LAMA4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6484, LAMA4

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000112769.18

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000112769

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501450643428 – 1816Sequence analysisAdd BLAST1789

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi101 ↔ 110PROSITE-ProRule annotation
Disulfide bondi157 ↔ 166PROSITE-ProRule annotation
Disulfide bondi212 ↔ 221PROSITE-ProRule annotation
Disulfide bondi224 ↔ 238PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
A0A0A0MTC7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000112769, Expressed in lung and 231 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0A0MTC7, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini82 – 131Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini132 – 186Laminin EGF-likeInterPro annotationAdd BLAST55
Domaini187 – 240Laminin EGF-likeInterPro annotationAdd BLAST54
Domaini826 – 1028LAM_G_DOMAINInterPro annotationAdd BLAST203
Domaini1040 – 1220LAM_G_DOMAINInterPro annotationAdd BLAST181
Domaini1227 – 1395LAM_G_DOMAINInterPro annotationAdd BLAST169
Domaini1462 – 1633LAM_G_DOMAINInterPro annotationAdd BLAST172
Domaini1640 – 1813LAM_G_DOMAINInterPro annotationAdd BLAST174

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1412 – 1433DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili332 – 359Sequence analysisAdd BLAST28
Coiled coili374 – 394Sequence analysisAdd BLAST21
Coiled coili471 – 498Sequence analysisAdd BLAST28
Coiled coili580 – 607Sequence analysisAdd BLAST28
Coiled coili659 – 682Sequence analysisAdd BLAST24
Coiled coili778 – 798Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159970

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002814_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
NCKGHAD

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR002049, Laminin_EGF
IPR001791, Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00053, Laminin_EGF, 3 hits
PF02210, Laminin_G_2, 5 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 3 hits
SM00180, EGF_Lam, 3 hits
SM00282, LamG, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899, SSF49899, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01248, EGF_LAM_1, 1 hit
PS50027, EGF_LAM_2, 3 hits
PS50025, LAM_G_DOMAIN, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

A0A0A0MTC7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALSSAWRSV LPLWLLWSAA CSRAASGDDN AFPFDIEGSS AVGRQDPPET
60 70 80 90 100
SEPRVALGRL PPAAEKCNAG FFHTLSGECV PCDCNGNSNE CLDGSGYCVH
110 120 130 140 150
CQRNTTGEHC EKCLDGYIGD SIRGAPQFCQ PCPCPLPHLA NFAESCYRKN
160 170 180 190 200
GAVRCICNEN YAGPNCERCA PGYYGNPLLI GSTCKKCDCS GNSDPNLIFE
210 220 230 240 250
DCDEVTGQCR NCLRNTTGFK CERCAPGYYG DARIAKNCAV CNCGGGPCDS
260 270 280 290 300
VTGECLEEGF EPPTGCDKCV WDLTDDLRLA ALSIEEGKSG VLSVSSGAAA
310 320 330 340 350
HRHVNEINAT IYLLKTKLSE RENQYALRKI QINNAENTMK SLLSDVEELV
360 370 380 390 400
EKENQASRKG QLVQKESMDT INHASQLVEQ AHDMRDKIQE INNKMLYYGE
410 420 430 440 450
EHELSPKEIS EKLVLAQKML EEIRSRQPFF TQRELVDEEA DEAYELLSQA
460 470 480 490 500
ESWQRLHNET RTLFPVVLEQ LDDYNAKLSD LQEALDQALN YVRDAEDMNR
510 520 530 540 550
ATAARQRDHE KQQERVREQM EVVNMSLSTS ADSLTTPRLT LSELDDIIKN
560 570 580 590 600
ASGIYAEIDG AKSELQVKLS NLSNLSHDLV QEAIDHAQDL QQEANELSRK
610 620 630 640 650
LHSSDMNGLV QKALDASNVY ENIVNYVSEA NETAEFALNT TDRIYDAVSG
660 670 680 690 700
IDTQIIYHKD ESENLLNQAR ELQAKAESSS DEAVADTSRR VGGALARKSA
710 720 730 740 750
LKTRLSDAVK QLQAAERGDA QQRLGQSRLI TEEANRTTME VQQATAPMAN
760 770 780 790 800
NLTNWSQNLQ HFDSSAYNTA VNSARDAVRN LTEVVPQLLD QLRTVEQKRP
810 820 830 840 850
ASNVSASIQR IRELIAQTRS VASKIQVSMM FDGQSAVEVH SRTSMDDLKA
860 870 880 890 900
FTSLSLYMKP PVKRPELTET ADQFILYLGS KNAKKEYMGL AIKNDNLVYV
910 920 930 940 950
YNLGTKDVEI PLDSKPVSSW PAYFSIVKIE RVGKHGKVFL TVPSLSSTAE
960 970 980 990 1000
EKFIKKGEFS GDDSLLDLDP EDTVFYVGGV PSNFKLPTSL NLPGFVGCLE
1010 1020 1030 1040 1050
LATLNNDVIS LYNFKHIYNM DPSTSVPCAR DKLAFTQSRA ASYFFDGSGY
1060 1070 1080 1090 1100
AVVRDITRRG KFGQVTRFDI EVRTPADNGL ILLMVNGSMF FRLEMRNGYL
1110 1120 1130 1140 1150
HVFYDFGFSG GPVHLEDTLK KAQINDAKYH EISIIYHNDK KMILVVDRRH
1160 1170 1180 1190 1200
VKSMDNEKMK IPFTDIYIGG APPEILQSRA LRAHLPLDIN FRGCMKGFQF
1210 1220 1230 1240 1250
QKKDFNLLEQ TETLGVGYGC PEDSLISRRA YFNGQSFIAS IQKISFFDGF
1260 1270 1280 1290 1300
EGGFNFRTLQ PNGLLFYYAS GSDVFSISLD NGTVIMDVKG IKVQSVDKQY
1310 1320 1330 1340 1350
NDGLSHFVIS SVSPTRYELI VDKSRVGSKN PTKGKIEQTQ ASEKKFYFGG
1360 1370 1380 1390 1400
SPISAQYANF TGCISNAYFT RVDRDVEVED FQRYTEKVHT SLYECPIESS
1410 1420 1430 1440 1450
PLFLLHKKGK NLSKPKASQN KKGGKSKDAP SWDPVALKLP ERNTPRNSHC
1460 1470 1480 1490 1500
HLSNSPRAIE HAYQYGGTAN SRQEFEHLKG DFGAKSQFSI RLRTRSSHGM
1510 1520 1530 1540 1550
IFYVSDQEEN DFMTLFLAHG RLVYMFNVGH KKLKIRSQEK YNDGLWHDVI
1560 1570 1580 1590 1600
FIRERSSGRL VIDGLRVLEE SLPPTEATWK IKGPIYLGGV APGKAVKNVQ
1610 1620 1630 1640 1650
INSIYSFSGC LSNLQLNGAS ITSASQTFSV TPCFEGPMET GTYFSTEGGY
1660 1670 1680 1690 1700
VVLDESFNIG LKFEIAFEVR PRSSSGTLVH GHSVNGEYLN VHMKNGQVIV
1710 1720 1730 1740 1750
KVNNGIRDFS TSVTPKQSLC DGRWHRITVI RDSNVVQLDV DSEVNHVVGP
1760 1770 1780 1790 1800
LNPKPIDHRE PVFVGGVPES LLTPRLAPSK PFTGCIRHFV IDGHPVSFSK
1810
AALVSGAVSI NSCPAA
Length:1,816
Mass (Da):201,820
Last modified:January 7, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i28D7E515B5B2153F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q16363LAMA4_HUMAN
Laminin subunit alpha-4
LAMA4
1,823Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MQS9A0A0A0MQS9_HUMAN
Laminin subunit alpha-4
LAMA4
1,823Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YAQ5H0YAQ5_HUMAN
Laminin subunit alpha-4
LAMA4
187Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y351H0Y351_HUMAN
Laminin subunit alpha-4
LAMA4
178Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RFQ2E5RFQ2_HUMAN
Laminin subunit alpha-4
LAMA4
331Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C139A0A494C139_HUMAN
Laminin subunit alpha-4
LAMA4
1,064Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6LET9Q6LET9_HUMAN
LAMA4 protein
LAMA4 hCG_32955
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHF3E5RHF3_HUMAN
Laminin subunit alpha-4
LAMA4
106Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RFD7E5RFD7_HUMAN
Laminin subunit alpha-4
LAMA4
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RK79E5RK79_HUMAN
Laminin subunit alpha-4
LAMA4
81Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL590106 Genomic DNA No translation available.
KF510935 Genomic DNA No translation available.
Z99289 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001098677.2, NM_001105207.2
NP_002281.3, NM_002290.4
XP_016866343.1, XM_017010854.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000389463; ENSP00000374114; ENSG00000112769
ENST00000424408; ENSP00000416470; ENSG00000112769
ENST00000522006; ENSP00000429488; ENSG00000112769

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3910

UCSC genome browser

More...
UCSCi
uc003pvt.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590106 Genomic DNA No translation available.
KF510935 Genomic DNA No translation available.
Z99289 Genomic DNA No translation available.
RefSeqiNP_001098677.2, NM_001105207.2
NP_002281.3, NM_002290.4
XP_016866343.1, XM_017010854.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiA0A0A0MTC7

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2846, 352 antibodies

The DNASU plasmid repository

More...
DNASUi
3910

Genome annotation databases

EnsembliENST00000389463; ENSP00000374114; ENSG00000112769
ENST00000424408; ENSP00000416470; ENSG00000112769
ENST00000522006; ENSP00000429488; ENSG00000112769
GeneIDi3910
UCSCiuc003pvt.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3910
HGNCiHGNC:6484, LAMA4
OpenTargetsiENSG00000112769
VEuPathDBiHostDB:ENSG00000112769.18

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000159970
HOGENOMiCLU_002814_0_0_1
OMAiNCKGHAD

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
3910, 5 hits in 990 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
LAMA4, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
3910

Gene expression databases

BgeeiENSG00000112769, Expressed in lung and 231 other tissues
ExpressionAtlasiA0A0A0MTC7, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR002049, Laminin_EGF
IPR001791, Laminin_G
PfamiView protein in Pfam
PF00053, Laminin_EGF, 3 hits
PF02210, Laminin_G_2, 5 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 3 hits
SM00180, EGF_Lam, 3 hits
SM00282, LamG, 5 hits
SUPFAMiSSF49899, SSF49899, 5 hits
PROSITEiView protein in PROSITE
PS01248, EGF_LAM_1, 1 hit
PS50027, EGF_LAM_2, 3 hits
PS50025, LAM_G_DOMAIN, 5 hits

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0A0MTC7_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0A0MTC7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: June 2, 2021
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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