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Protein
Submitted name:

Double-stranded RNA-binding protein Staufen homolog 2

Gene

STAU2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Double-stranded RNA-binding protein Staufen homolog 2Imported
Gene namesi
Name:STAU2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000040341.17
HGNCiHGNC:11371 STAU2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000040341

PTM / Processingi

Proteomic databases

EPDiA0A0A0MTC6
PRIDEiA0A0A0MTC6

Expressioni

Gene expression databases

BgeeiENSG00000040341 Expressed in 221 organ(s), highest expression level in frontal cortex
ExpressionAtlasiA0A0A0MTC6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0A0MTC6
SMRiA0A0A0MTC6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 77DRBMInterPro annotationAdd BLAST36
Domaini103 – 170DRBMInterPro annotationAdd BLAST68
Domaini203 – 271DRBMInterPro annotationAdd BLAST69

Family and domain databases

CDDicd00048 DSRM, 3 hits
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR032478 Staufen_C
PfamiView protein in Pfam
PF00035 dsrm, 3 hits
PF16482 Staufen_C, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 3 hits
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

A0A0A0MTC6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRGEPAIYR PLDPKPFPNY RANYNFRGMY NQRYHCPVPK IFYVQLTVGN
60 70 80 90 100
NEFFGEGKTR QAARHNAAMK ALQALQNEPI PERSPQNGES GKDVDDDKDA
110 120 130 140 150
NKSEISLVFE IALKRNMPVS FEVIKESGPP HMKSFVTRVS VGEFSAEGEG
160 170 180 190 200
NSKKLSKKRA ATTVLQELKK LPPLPVVEKP KLFFKKRPKT IVKAGPEYGQ
210 220 230 240 250
GMNPISRLAQ IQQAKKEKEP DYVLLSERGM PRRREFVMQV KVGNEVATGT
260 270 280 290 300
GPNKKIAKKN AAEAMLLQLG YKASTNLQDQ LEKTGENKGW SGPKPGFPEP
310 320 330 340 350
TNNTPKGILH LSPDVYQEME ASRHKVISGT TLGYLSPKDM NQPSSSFFSI
360 370 380 390 400
SPTSNSSATI ARELLMNGTS STAEAIGLKG SSPTPPCSPV QPSKQLEYLA
410 420 430 440 450
RIQGFQVHYC DRQSGKECVT CLTLAPVQMT FHAIGSSIEA SHDQAALSAL
460 470 480 490 500
KQFSEQGLDP IDGAMNIEKG SLEKQAKHLR EKADNNQAPP GSIAQDCKKS

NSAV
Length:504
Mass (Da):55,414
Last modified:January 7, 2015 - v1
Checksum:iCA38078E7E7DA03A
GO

Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NUL3STAU2_HUMAN
Double-stranded RNA-binding protein...
STAU2
570Annotation score:
E9PH62E9PH62_HUMAN
Double-stranded RNA-binding protein...
STAU2
538Annotation score:
A0A0A0MTC4A0A0A0MTC4_HUMAN
Double-stranded RNA-binding protein...
STAU2
398Annotation score:
A0A0A0MTD1A0A0A0MTD1_HUMAN
Double-stranded RNA-binding protein...
STAU2
473Annotation score:
E5RFK1E5RFK1_HUMAN
Double-stranded RNA-binding protein...
STAU2
204Annotation score:
E5RJN7E5RJN7_HUMAN
Double-stranded RNA-binding protein...
STAU2
320Annotation score:
G5EA18G5EA18_HUMAN
Double-stranded RNA-binding protein...
STAU2
291Annotation score:
F8VPI7F8VPI7_HUMAN
Double-stranded RNA-binding protein...
STAU2
479Annotation score:
E5RJ67E5RJ67_HUMAN
Double-stranded RNA-binding protein...
STAU2
135Annotation score:
E7EVI1E7EVI1_HUMAN
Double-stranded RNA-binding protein...
STAU2
390Annotation score:
There are more potential isoformsShow all

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018620 Genomic DNA No translation available.
AC027018 Genomic DNA No translation available.
AC100784 Genomic DNA No translation available.
KF458781 Genomic DNA No translation available.
RefSeqiNP_001157854.1, NM_001164382.1
UniGeneiHs.561815

Genome annotation databases

EnsembliENST00000521210; ENSP00000429173; ENSG00000040341
GeneIDi27067
UCSCiuc011lfh.3 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018620 Genomic DNA No translation available.
AC027018 Genomic DNA No translation available.
AC100784 Genomic DNA No translation available.
KF458781 Genomic DNA No translation available.
RefSeqiNP_001157854.1, NM_001164382.1
UniGeneiHs.561815

3D structure databases

ProteinModelPortaliA0A0A0MTC6
SMRiA0A0A0MTC6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiA0A0A0MTC6
PRIDEiA0A0A0MTC6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521210; ENSP00000429173; ENSG00000040341
GeneIDi27067
UCSCiuc011lfh.3 human

Organism-specific databases

CTDi27067
EuPathDBiHostDB:ENSG00000040341.17
HGNCiHGNC:11371 STAU2
OpenTargetsiENSG00000040341
GenAtlasiSearch...

Miscellaneous databases

ChiTaRSiSTAU2 human
GenomeRNAii27067

Gene expression databases

BgeeiENSG00000040341 Expressed in 221 organ(s), highest expression level in frontal cortex
ExpressionAtlasiA0A0A0MTC6 baseline and differential

Family and domain databases

CDDicd00048 DSRM, 3 hits
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR032478 Staufen_C
PfamiView protein in Pfam
PF00035 dsrm, 3 hits
PF16482 Staufen_C, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 3 hits
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0A0MTC6_HUMAN
AccessioniPrimary (citable) accession number: A0A0A0MTC6
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: September 12, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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