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Protein
Submitted name:

Band 3 anion transport protein

Gene

SLC4A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Band 3 anion transport proteinImported
Gene namesi
Name:SLC4A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000004939.13
HGNCiHGNC:11027 SLC4A1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei293 – 314HelicalSequence analysisAdd BLAST22
Transmembranei335 – 358HelicalSequence analysisAdd BLAST24
Transmembranei421 – 445HelicalSequence analysisAdd BLAST25
Transmembranei465 – 484HelicalSequence analysisAdd BLAST20
Transmembranei491 – 512HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000004939

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0A0MS98
PRIDEiA0A0A0MS98

Expressioni

Gene expression databases

BgeeiENSG00000004939 Expressed in 131 organ(s), highest expression level in trabecular bone tissue
ExpressionAtlasiA0A0A0MS98 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0A0MS98
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 257Band_3_cytoInterPro annotationAdd BLAST170
Domaini261 – 473HCO3_cotranspInterPro annotationAdd BLAST213

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 21Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1172 Eukaryota
ENOG410XPHD LUCA
GeneTreeiENSGT00760000119021

Family and domain databases

Gene3Di3.40.930.10, 1 hit
InterProiView protein in InterPro
IPR013769 Band3_cytoplasmic_dom
IPR011531 HCO3_transpt_C
IPR003020 HCO3_transpt_euk
IPR016152 PTrfase/Anion_transptr
PANTHERiPTHR11453 PTHR11453, 2 hits
PfamiView protein in Pfam
PF07565 Band_3_cyto, 1 hit
PF00955 HCO3_cotransp, 1 hit
PRINTSiPR01231 HCO3TRNSPORT
SUPFAMiSSF55804 SSF55804, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A0A0MS98-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELQDDYED MMEENLEQEE YEDPDIPESQ MEEPAAHDTE ATATDYHTTS
60 70 80 90 100
HPGTHKVYVE LQELVMDEKN QELRWMEAAR WVQLEENLGE NGAWGRPHLS
110 120 130 140 150
HLTFWSLLEL RRVFTKGTVL LDLQETSLAG VANQLLDRFI FEDQIRPQDR
160 170 180 190 200
EELLRALLLK HSHAGELEAL GGVKPAVLTR SGDPSQPLLP QHSSLETQLF
210 220 230 240 250
CEQGDGGTEG HSPSGILEKI PPDSEATLVL VGRADFLEQP VLGFVRLQEA
260 270 280 290 300
AELEAVELPD TYTQKLSVPD GFKVSNSSAR GWVIHPLGLR SEFPIWMMFA
310 320 330 340 350
SALPALLVFI LIFLESQITT LIVSKPERKM VKGSGFHLDL LLVVGMGGVA
360 370 380 390 400
ALFGMPWLSA TTVRSVTHAN ALTVMGKAST PGAAAQIQEV KEQRISGLLV
410 420 430 440 450
AVLVGLSILM EPILSRIPLA VLFGIFLYMG VTSLSGIQLF DRILLLFKPP
460 470 480 490 500
KYHPDVPYVK RVKTWRMHLF TGIQIICLAV LWVVKSTPAS LALPFVLILT
510 520 530 540
VPLRRVLLPL IFRNVELQCL DADDAKATFD EEEGRDEYDE VAMPV
Length:545
Mass (Da):60,764
Last modified:January 7, 2015 - v1
Checksum:i88F1398B59D85709
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P02730B3AT_HUMAN
Band 3 anion transport protein
SLC4A1 AE1, DI, EPB3
911Annotation score:
V9H0V9V9H0V9_HUMAN
Anion exchanger
SLC4A1
36Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003043 Genomic DNA No translation available.
AC003102 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000399246; ENSP00000382190; ENSG00000004939
UCSCiuc021tyc.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003043 Genomic DNA No translation available.
AC003102 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A0A0MS98
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A0A0MS98
PRIDEiA0A0A0MS98

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000399246; ENSP00000382190; ENSG00000004939
UCSCiuc021tyc.2 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000004939.13
HGNCiHGNC:11027 SLC4A1
OpenTargetsiENSG00000004939
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1172 Eukaryota
ENOG410XPHD LUCA
GeneTreeiENSGT00760000119021

Miscellaneous databases

ChiTaRSiSLC4A1 human

Gene expression databases

BgeeiENSG00000004939 Expressed in 131 organ(s), highest expression level in trabecular bone tissue
ExpressionAtlasiA0A0A0MS98 baseline and differential

Family and domain databases

Gene3Di3.40.930.10, 1 hit
InterProiView protein in InterPro
IPR013769 Band3_cytoplasmic_dom
IPR011531 HCO3_transpt_C
IPR003020 HCO3_transpt_euk
IPR016152 PTrfase/Anion_transptr
PANTHERiPTHR11453 PTHR11453, 2 hits
PfamiView protein in Pfam
PF07565 Band_3_cyto, 1 hit
PF00955 HCO3_cotransp, 1 hit
PRINTSiPR01231 HCO3TRNSPORT
SUPFAMiSSF55804 SSF55804, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0A0MS98_HUMAN
AccessioniPrimary (citable) accession number: A0A0A0MS98
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: September 12, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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