UniProtKB - A0A0A0MRR5 (A0A0A0MRR5_HUMAN)
Protein
Submitted name:
Uracil phosphoribosyltransferase homolog
Gene
UPRT
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Uracil phosphoribosyltransferase homologImported |
Gene namesi | ORF Names:hCG_20330Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:28334, UPRT |
VEuPathDBi | HostDB:ENSG00000094841.13 |
Subcellular locationi
Nucleus
- nucleoplasm Source: HPA
Other locations
- intracellular membrane-bounded organelle Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000094841, Expressed in quadriceps femoris and 207 other tissues |
ExpressionAtlasi | A0A0A0MRR5, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 38 | DisorderedSequence analysisAdd BLAST | 38 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 9 – 27 | PolarSequence analysisAdd BLAST | 19 |
Phylogenomic databases
GeneTreei | ENSGT01010000222379 |
Family and domain databases
CDDi | cd06223, PRTases_typeI, 1 hit |
Gene3Di | 3.40.50.2020, 1 hit |
InterProi | View protein in InterPro IPR000836, PRibTrfase_dom IPR029057, PRTase-like |
SUPFAMi | SSF53271, SSF53271, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
A0A0A0MRR5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATELQCPDS MPCHNQQVNS ASTPSPEQLR PGDLILDHAG GNRASRAKVI
60 70 80 90 100
LLTGYAHSSL PAELDSGACG GSSLNSEGNS GSGDSSSYDA PAGNSFLEDC
110 120 130 140 150
ELSRQIGAQL KLLPMNDQIR ELQTIIRDKT ASRGDFMFSA DRLIRLVVEE
160 170 180 190 200
GLNQLPYKEC MVTTPTGYKY EGVKFEKGNC GVSIMRSGEA MEQGLRDCCR
210 220 230 240 250
SIRIGKILIQ SDEETQRAKV YYAKFPPDIY RRKVLLMYPI LSTGNTVIEA
260 270 280
VKVLIEHGVQ PSVIILLSLF STPHGEFSMR Q
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ96BW1 | UPP_HUMAN | Uracil phosphoribosyltransferase ho... | UPRT | 309 | Annotation score: | ||
E9PSD7 | E9PSD7_HUMAN | Uracil phosphoribosyltransferase ho... | UPRT | 173 | Annotation score: | ||
F8W6E9 | F8W6E9_HUMAN | Uracil phosphoribosyltransferase ho... | UPRT | 142 | Annotation score: | ||
A0A494C0H3 | A0A494C0H3_HUMAN | Uracil phosphoribosyltransferase ho... | UPRT | 149 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL137013 Genomic DNA No translation available. AL360179 Genomic DNA No translation available. AL590234 Genomic DNA No translation available. CH471104 Genomic DNA Translation: EAW98630.1 |
RefSeqi | NP_001294873.1, NM_001307944.1 |
Genome annotation databases
Ensembli | ENST00000373379; ENSP00000362477; ENSG00000094841 |
GeneIDi | 139596 |
UCSCi | uc004ecd.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL137013 Genomic DNA No translation available. AL360179 Genomic DNA No translation available. AL590234 Genomic DNA No translation available. CH471104 Genomic DNA Translation: EAW98630.1 |
RefSeqi | NP_001294873.1, NM_001307944.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | A0A0A0MRR5 |
Protocols and materials databases
Antibodypediai | 361, 256 antibodies |
Genome annotation databases
Ensembli | ENST00000373379; ENSP00000362477; ENSG00000094841 |
GeneIDi | 139596 |
UCSCi | uc004ecd.3, human |
Organism-specific databases
CTDi | 139596 |
HGNCi | HGNC:28334, UPRT |
OpenTargetsi | ENSG00000094841 |
VEuPathDBi | HostDB:ENSG00000094841.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT01010000222379 |
Miscellaneous databases
BioGRID-ORCSi | 139596, 3 hits in 500 CRISPR screens |
ChiTaRSi | UPRT, human |
GenomeRNAii | 139596 |
Gene expression databases
Bgeei | ENSG00000094841, Expressed in quadriceps femoris and 207 other tissues |
ExpressionAtlasi | A0A0A0MRR5, baseline and differential |
Family and domain databases
CDDi | cd06223, PRTases_typeI, 1 hit |
Gene3Di | 3.40.50.2020, 1 hit |
InterProi | View protein in InterPro IPR000836, PRibTrfase_dom IPR029057, PRTase-like |
SUPFAMi | SSF53271, SSF53271, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0A0MRR5_HUMAN | |
Accessioni | A0A0A0MRR5Primary (citable) accession number: A0A0A0MRR5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 7, 2015 |
Last sequence update: | January 7, 2015 | |
Last modified: | February 10, 2021 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |