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Protein
Submitted name:

Prostaglandin E2 receptor EP3 subtype

Gene

PTGER3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin E2 receptor EP3 subtypeImported
Gene namesi
Name:PTGER3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000050628.20
HGNCiHGNC:9595 PTGER3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 75HelicalSequence analysisAdd BLAST24
Transmembranei87 – 112HelicalSequence analysisAdd BLAST26
Transmembranei132 – 153HelicalSequence analysisAdd BLAST22
Transmembranei173 – 194HelicalSequence analysisAdd BLAST22
Transmembranei228 – 253HelicalSequence analysisAdd BLAST26
Transmembranei284 – 307HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000050628

Expressioni

Gene expression databases

BgeeiENSG00000050628
ExpressionAtlasiA0A0A0MRP3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0A0MRP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 346G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST282

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000119188

Family and domain databases

InterProiView protein in InterPro
IPR001481 EP3_rcpt_2
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR008365 Prostanoid_rcpt
IPR001244 Prostglndn_DP_rcpt
IPR000265 Prostglndn_EP3_rcpt
PANTHERiPTHR11866 PTHR11866, 1 hit
PTHR11866:SF10 PTHR11866:SF10, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00428 PROSTAGLNDNR
PR01788 PROSTANOIDR
PR00584 PRSTNOIDE32R
PR00582 PRSTNOIDEP3R
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0A0MRP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKETRGYGGD APFCTRLNHS YTGMWAPERS AEARGNLTRP PGSGEDCGSV
60 70 80 90 100
SVAFPITMLL TGFVGNALAM LLVSRSYRRR ESKRKKSFLL CIGWLALTDL
110 120 130 140 150
VGQLLTTPVV IVVYLSKQRW EHIDPSGRLC TFFGLTMTVF GLSSLFIASA
160 170 180 190 200
MAVERALAIR APHWYASHMK TRATRAVLLG VWLAVLAFAL LPVLGVGQYT
210 220 230 240 250
VQWPGTWCFI STGRGGNGTS SSHNWGNLFF ASAFAFLGLL ALTVTFSCNL
260 270 280 290 300
ATIKALVSRC RAKATASQSS AQWGRITTET AIQLMGIMCV LSVCWSPLLI
310 320 330 340 350
MMLKMIFNQT SVEHCKTHTE KQKECNFFLI AVRLASLNQI LDPWVYLLLR
360 370 380
KILLRKFCQV ANAVSFSRRN FGEIKTCLSA RITSLEAP
Length:388
Mass (Da):42,859
Last modified:January 7, 2015 - v1
Checksum:iEA549209B61404B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031429 Genomic DNA No translation available.
AL158087 Genomic DNA No translation available.
KF454969 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000370932; ENSP00000359970; ENSG00000050628
UCSCiuc057hmm.1 human

Similar proteinsi

Entry informationi

Entry nameiA0A0A0MRP3_HUMAN
AccessioniPrimary (citable) accession number: A0A0A0MRP3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: May 23, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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