UniProtKB - A0A0A0MRJ5 (A0A0A0MRJ5_HUMAN)
Protein
Submitted name:
Troponin T, cardiac muscle
Gene
TNNT2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Troponin T, cardiac muscleImported |
Gene namesi | Name:TNNT2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000118194.18 |
HGNCi | HGNC:11949 TNNT2 |
Subcellular locationi
Cytoskeleton
- troponin complex Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSG00000118194 Expressed in 165 organ(s), highest expression level in cardiac ventricle |
ExpressionAtlasi | A0A0A0MRJ5 baseline and differential |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1 – 53 | Sequence analysisAdd BLAST | 53 | |
Coiled coili | 87 – 173 | Sequence analysisAdd BLAST | 87 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG3634 Eukaryota ENOG410XS6A LUCA |
GeneTreei | ENSGT00940000154709 |
OrthoDBi | 1480247at2759 |
Family and domain databases
Gene3Di | 1.20.5.350, 1 hit |
InterProi | View protein in InterPro IPR027707 TNNT IPR001978 Troponin IPR038077 Troponin_sf |
PANTHERi | PTHR11521 PTHR11521, 1 hit |
Pfami | View protein in Pfam PF00992 Troponin, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
A0A0A0MRJ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDIEEVVEE YEEEEQEEQE EAAEEDAEAE AETEETRAEE DEEEEEAKEA
60 70 80 90 100
EDGPMEESKP KPRSFMPNLV PPKIPDGERV DFDDIHRKRM EKDLNELQAL
110 120 130 140 150
IEAHFENRKK EEEELVSLKD RIERRRAERA EQQRIRNERE KERQNRLAEE
160 170 180 190 200
RARREEEENR RKAEDEARKK KALSNMMHFG GYIQKAQTER KSGKRQTERE
210 220 230 240 250
KKKKILAERR KVLAIDHLNE DQLREKAKEL WQSIYNLEAE KFDLQEKFKQ
260 270 280
QKYEINVLRN RINDNQKVSK TRGKAKVTGR WK
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP45379 | TNNT2_HUMAN | Troponin T, cardiac muscle | TNNT2 | 298 | Annotation score: | ||
Q7Z554 | Q7Z554_HUMAN | Troponin T cardiac isoform | TNNT2 HNTN1, hCG_1641227 | 226 | Annotation score: | ||
E7EPW4 | E7EPW4_HUMAN | Troponin T, cardiac muscle | TNNT2 | 271 | Annotation score: | ||
C9JDF8 | C9JDF8_HUMAN | Troponin T, cardiac muscle | TNNT2 | 114 | Annotation score: | ||
E7EPN8 | E7EPN8_HUMAN | Troponin T, cardiac muscle | TNNT2 | 180 | Annotation score: | ||
A0A0A0MRJ4 | A0A0A0MRJ4_HUMAN | Troponin T, cardiac muscle | TNNT2 | 291 | Annotation score: | ||
C9JM61 | C9JM61_HUMAN | Troponin T, cardiac muscle | TNNT2 | 97 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC119427 Genomic DNA No translation available. |
RefSeqi | NP_001001432.1, NM_001001432.2 |
UniGenei | Hs.533613 |
Genome annotation databases
Ensembli | ENST00000367317; ENSP00000356286; ENSG00000118194 |
GeneIDi | 7139 |
UCSCi | uc057ohg.1 human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC119427 Genomic DNA No translation available. |
RefSeqi | NP_001001432.1, NM_001001432.2 |
UniGenei | Hs.533613 |
3D structure databases
ProteinModelPortali | A0A0A0MRJ5 |
ModBasei | Search... |
MobiDBi | Search... |
Proteomic databases
PRIDEi | A0A0A0MRJ5 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENST00000367317; ENSP00000356286; ENSG00000118194 |
GeneIDi | 7139 |
UCSCi | uc057ohg.1 human |
Organism-specific databases
CTDi | 7139 |
EuPathDBi | HostDB:ENSG00000118194.18 |
HGNCi | HGNC:11949 TNNT2 |
OpenTargetsi | ENSG00000118194 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3634 Eukaryota ENOG410XS6A LUCA |
GeneTreei | ENSGT00940000154709 |
OrthoDBi | 1480247at2759 |
Miscellaneous databases
ChiTaRSi | TNNT2 human |
GenomeRNAii | 7139 |
Gene expression databases
Bgeei | ENSG00000118194 Expressed in 165 organ(s), highest expression level in cardiac ventricle |
ExpressionAtlasi | A0A0A0MRJ5 baseline and differential |
Family and domain databases
Gene3Di | 1.20.5.350, 1 hit |
InterProi | View protein in InterPro IPR027707 TNNT IPR001978 Troponin IPR038077 Troponin_sf |
PANTHERi | PTHR11521 PTHR11521, 1 hit |
Pfami | View protein in Pfam PF00992 Troponin, 2 hits |
ProtoNeti | Search... |
Entry informationi
Entry namei | A0A0A0MRJ5_HUMAN | |
Accessioni | A0A0A0MRJ5Primary (citable) accession number: A0A0A0MRJ5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 7, 2015 |
Last sequence update: | January 7, 2015 | |
Last modified: | January 16, 2019 | |
This is version 30 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |